Chronic lymphocytic leukaemia (CLL)

Required sample material

Leukaemia diagnostics - classic cytogenetics:
5-7 ml heparinised peripheral blood (no bone marrow)
_{NH4-Heparinate} S-Monovettes (Sarstedt REF 01.1603) or disposable syringes with approx. 20 to max. 200 µl heparin sodium (5000 I.U./ml) (final concentration 10 to max. 100 I.U. heparin/ml sample material) Please do not send Li heparin blood or EDTA blood!

Leukaemia diagnostics - molecular cytogenetics:
3-4 ml heparinised peripheral blood (no bone marrow)

 

Sample dispatch

Heparinised whole blood for cytogenetic and molecular cytogenetic tests should be sent by express without refrigeration. The sample transport time is of greater importance in cytogenetics, as cell cultures almost always have to be created here. The test material should reach the laboratory within 24 hours.

Please send the samples to the following address:

Heidelberg University Hospital
Institute of Human Genetics

depending on the test requested:

Laboratory for Molecular Cytogenetics/ or
Laboratory for Cytogenetic Diagnostics

Im Neuenheimer Feld 366
69120 Heidelberg

Sample labelling

Please label each sample container clearly with the surname, first name and date of birth of the patient and use our request forms.

The request forms are structured in such a way that we have all the necessary information about the patient and the patient consent form (where required) for the examination order.

Please complete the request forms carefully to avoid unnecessary enquiries and please understand that we cannot accept unlabelled sample containers.

Leukaemia and lymphoproliferative diseases request form

Further information

Examination method:
Depending on the problem, both molecular cytogenetic and cytogenetic examinations are indicated. Using FISH diagnostics, chromosomal aberrations can be detected in 80% of patients.

Literature:
Atlas of Genetics and Cytogenetics in Oncology and Haematology

OMIM:151400

Processing time:
Molecular cytogenetic analysis: 1-2 weeks after receipt of order
Cytogenetic analysis: 2-3 weeks

Contact persons