Myeloproliferative diseases (MPS)**

Required sample material

Leukaemia diagnostics - classic cytogenetics:
5-7 ml bone marrow aspirate (NH4 or Na heparin) NH4 heparinate S monovettes (Sarstedt REF 01.1603) or disposable syringes with approx. 20 to max. 200 µl heparin sodium (5000 I.U./ml) (final concentration 10 to max. 100 I.U. heparin/ml sample material). Please do not send Li heparin or EDTA blood.

Leukaemia diagnostics - molecular cytogenetics:
3-4 ml bone marrow aspirate (NH4 heparin)
NH4 heparinate S monovettes (Sarstedt REF 01.1603) or disposable syringes with approx. 20 to max. 200 µl heparin sodium (5000 I.U./ml) (final concentration 10 to max. 100 I.U. heparin/ml sample material). Please do not send Li heparin or EDTA blood.

Leukaemia diagnostics - MRD
see request form

Sample dispatch

Samples for RNA/cDNA analyses in molecular genetic leukaemia diagnostics should be sent unrefrigerated as quickly as possible (preferably by express).

Heparin whole blood for cytogenetic and molecular cytogenetic analyses should be sent by express without refrigeration. The sample transport time is of greater importance in cytogenetics, as cell cultures almost always have to be created here. The test material should reach the laboratory within 24 hours.

Heparin bone marrow aspirate for cytogenetic and molecular cytogenetic analyses should be sent unrefrigerated by express mail. The sample transport time is of greater importance in cytogenetics, as cell cultures almost always have to be created here. The test material should reach the laboratory within 24 hours.

Please send the samples to the following address:

Heidelberg University Hospital
Institute of Human Genetics

depending on the test requested:

Laboratory for Molecular Genetic Diagnostics/
Laboratory for Molecular Cytogenetics/
Laboratory for Cytogenetic Diagnostics/
Laboratory for MRD Diagnostics

Im Neuenheimer Feld 366 (4th floor)
69120 Heidelberg

Sample labelling

Please label each sample container clearly with the surname, first name and date of birth of the patient and use our request forms.

The request forms are structured in such a way that we have all the necessary information about the patient and the patient consent form (where required) for the test order.

Please complete the request forms carefully to avoid unnecessary enquiries and please understand that we cannot accept unlabelled sample containers.

Leukaemia and lymphoproliferative diseases request form

Further information

Examination method:
Depending on the problem, molecular genetic, molecular cytogenetic and cytogenetic examinations are indicated.

Literature:
Atlas of Genetics and Cytogenetics in Oncology and Haematology

OMIM: 263300, 187950, 254450

Processing time:
Molecular cytogenetic examination: 1-2 weeks after receipt of order
Molecular genetic examination: 5-14 days
Cytogenetic examination: 2-3 weeks

Contact person

** only the molecular genetic test is not accredited