Arbeitsgruppe Molekulare Immundiagnostik
Forschungsschwerpunkte
- Pharmakodynamisches Monitoring der NFAT-abhängigen Genexpression nach Einnahme von Calcineurininhibitoren
Kooperation Nierenzentrum: Prof. C. Sommerer, Prof. M. Zeier
- Primäre Immundefekte
Kooperation Kinderklinik PD Dr. J. Greil
- Immunvermittelte entzündliche Erkrankungen
Kooperation Sektion Rheumatologie: Prof. H. Lorenz
- Immunphänotypisierung und molekulare Diagnostik des Pankreaskarzinoms
Kooperation Europäisches Pankreaszentrum: Dr. N. Giese
- Infektionen im immungeschwächten Wirt (DZIF Projekt 07.801)
Mitarbeiter/-innen
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Lisa Krupp
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Sven Rüffer
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Henrike Weigold
Publikationen
- Lovric, S. et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest 127, 912-928 (2017).
- Keller, F., Sommerer, C., Giese, T., Zeier, M. & Schroppel, B. Correlation between pharmacokinetics of tacrolimus and pharmacodynamics on NFATregulated gene expression in stable kidney transplant recipients. Clin Nephrol 87 (2017), 93-99 (2017).
- Sommerer, C. & Giese, T. Nuclear Factor of Activated T Cells-Regulated Gene Expression as Predictive Biomarker of Personal Response to Calcineurin Inhibitors. Ther Drug Monit 38 Suppl 1, S50-56 (2016).
- Rossnagl, S. et al. EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer. PLoS Biol 14, e1002562 (2016).
- Radujkovic, A. et al. Expression of CDKN1C in the bone marrow of patients with myelodysplastic syndrome and secondary acute myeloid leukemia is associated with poor survival after conventional chemotherapy. Int J Cancer 139, 1402-1413 (2016).
- Klein, K. et al. Role of TFEB-driven autophagy regulation in pancreatic cancer treatment. Int J Oncol 49, 164-172 (2016).
- Heller, A. et al. Establishment and Characterization of a Novel Cell Line, ASAN-PaCa, Derived From Human Adenocarcinoma Arising in Intraductal Papillary Mucinous Neoplasm of the Pancreas. Pancreas 45, 1452-1460 (2016).
- Friedrich, K. et al. CD14 is associated with biliary stricture formation. Hepatology 64, 843-852 (2016).
Ausgewählte Publikationen können in PubMed angeschaut werden.