Publikationen 2024
Claudius Gottschalk - Marija Stojković - Sabine Zange - Peter Wolf - Julian A. F. Klein
A case of pulmonary melioidosis in Germany: a rare differential diagnosis in returning travelers from South-East Asia
Infection, 26 April 2024. doi: 10.1007/s15010-024-02253-6
Julia Körholz - Lan-Sun Chen - Timmy Strauss - Catharina Schuetz - Alexander H. Dalpke
One gene to rule them all – clinical perspectives of a potent suppressor of cytokine signaling – SOCS1
Frontiers in Immunology, 22 April 2024. doi: 10.3389/fimmu.2024.1385190
Angélica M. Olmo-Fontánez - Julia M. Scordo - Alyssa Schami - Andreu Garcia-Vilanova - Paula A. Pino - Amberlee Hicks - Richa Mishra - Diego Jose Maselli - Jay I. Peters - Blanca I. Restrepo - Kievershen Nargan - Threnesan Naidoo - Daniel L. Clemens - Adrie J.C. Steyn - Vivek V. Thacker - Joanne Turner - Larry S. Schlesinger - Jordi B. Torrelles
Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells
Mucosal Immunol, 2 April 2024. doi: 10.1016/j.mucimm.2024.01.001
Andrew Tony-Odigie - Alexander H Dalpke - Sébastien Boutin - Buqing Yi
Airway commensal bacteria in cystic fibrosis inhibit the growth of P. aeruginosa via a released metabolite
Microbiol Res, 09 March 2024. doi: 10.1016/j.micres.2024.127680
S Boutin - M Scherrer - I Späth - K Kocer - K Heeg - D Nurjadi
Cross-contamination of carbapenem-resistant Gram-negative bacteria between patients and the hospital environment in the first year of a newly built surgical ward
J Hosp Infect, Februar 2024. doi: 10.1016/j.jhin.2023.11.016
C. Bundschuh - N. Weidner - J. Klein - T. Rausch - N. Azevedo - A. Telzerow - J. P. Mallm - H. Kim - S. Steiger - I. Seufert - K. Borner - K. Bauer - D. Hubschmann - K. L. Jost - S. Parthe - P. Schnitzler - M. Boutros - K. Rippe - B. Muller - R. Bartenschlager - H. G. Krausslich - V. Benes
Evolution of SARS-CoV-2 in the Rhine-Neckar/Heidelberg Region 01/2021 - 07/2023
Infect Genet Evol, 23. Februar 2024. doi: 10.1016/j.micres.2024.127680
Julia Werner - Florian Umstätter - Tobias Hertlein - Barbro Beijer - Christian Kleist - Eric Mühlberg - Stefan Zimmermann - Uwe Haberkorn - Knut Ohlsen - Gert Fricker - Walter Mier - Philipp Uhl
Improved pharmacokinetics and enhanced efficacy of the vancomycin derivative FU002 using a liposomal nanocarrier
Nanomedicine, Februar 2024. doi: 10.1016/j.nano.2023.102731
Publikationen 2023
Katharina F. Kubatzky - Yue Gao - Dayoung Yu
Post-translational modulation of cell signalling through protein succinylation
Explor Target Antitumor Ther, 27 Dezember 2023. doi: 10.37349/etat.2023.00196
de la Cruz Barron,Magali - Kneis,David - Geissler,Michael - Dumke,Roger - Dalpke,Alexander - Berendonk,Thomas U.
Evaluating the sensitivity of droplet digital PCR for the quantification of SARS-CoV-2 in wastewater
Frontiers in Public Health. 27 Dezember 2023. doi: 10.3389/fpubh.2023.1271594
Cizmic, A. - Eichel, V. M. - Weidner, N. M. - Wise, P. A. - Muller, F. - Rompen, I. F. - Bartenschlager, R. - Schnitzler, P. - Nickel, F. -
Muller-Stich, B. P.
Viral load of SARS-CoV-2 in surgical smoke in minimally invasive and open surgery: a single-center prospective clinical trial
Scientific reports. 20 November 2023 doi: 10.1038/s41598-023-47058-z
Helm, M. - Bohnsack, M. T. - Carell, T. - Dalpke, A. - Entian, K. D. - Ehrenhofer-Murray, A. - Ficner, R. - Hammann, C. - Hobartner, C. - Jaschke, A. - Jeltsch, A. - Kaiser, S. - Klassen, R. - Leidel, S. A. - Marx, A. - Morl, M. - Meier, J. C. - Meister, G. - Rentmeister, A. - Rodnina, M. - Roignant, J. Y. - Schaffrath, R. - Stadler, P. - Stafforst, T.
Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications
American Chemical Society. 14 November 2023. doi: 10.1021/acschembio.3c00586
Sultanli, S. Schneider, J. Burkart, S. S. Binder, M. Kubatzky, K. F.
Cellular ROS tolerance determines the effect of plumbagin on osteoclast differentiation
FASEB Journal, 11 November 2023 doi: 10.1096/fj.202301415R
Richa Mishra - Melanie Hannebelle - Vishal P Patil - Anaëlle Dubois - Cristina Garcia-Mouton - Gabriela M Kirsch - Maxime Jan - Kunal Sharma - Nicolas Guex - Jessica Sordet-Dessimoz - Jesus Perez-Gil - Manu Prakash - Graham W Knott - Neeraj Dhar - John D McKinney - Vivek V Thacker
Mechanopathology of biofilm-like Mycobacterium tuberculosis cords
Cell, 9 November 2023. doi: 10.1016/j.cell.2023.09.016
Chakraborty, S. - Gupta, R. - Kubatzky, K. F. - Kar, S. - Kraus, F. V. - Souto-Carneiro, M. M. - Lorenz, H. M. - Kumar, P. - Kumar, V. - Mitra, D. K.
Negative impact of Interleukin-9 on synovial regulatory T cells in rheumatoid arthritis
Clinical Immunology, 23 Oktober 2023. doi: 10.1016/j.clim.2023.109814
Nurjadi, D. - Eichel, V. M. - Poschl, J. - Gille, C. - Kranig, S. - Heeg, K. - Boutin, S.
Monocentric observational cohort study to investigate the transmission of third-generation cephalosporin-resistant Enterobacterales in a neonatal intensive care unit in Heidelberg, Germany
Microbiology spectrum, 22 September 2023. doi: 10.1128/spectrum.02038-23
Seebach, Elisabeth - Sonnenmoser, Gabriele - Kubatzky, Katharina F.
Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway
Virulence - Taylor & Francis, 11 September 2023. doi: 10.1080/21505594.2023.2254599
Theresa S Horst - Jakob P Armann - Maren Doenhardt - Svenja Dreßen - Paula Czyborra - Josephine Schneider - Christin Gano - Alexander Dalpke - Christian Lück - Annet Bluschke - Magdalena Wekenborg - Reinhard Berner - Judith Blankenburg
FamilyCoviDD19: results of a cross-sectional study-long-term outcomes of infected and uninfected household members
Fam Med Community Health, 11 September 2023. doi: 10.1136/fmch-2022-002057
Quintana, Juan F. - Sinton, Matthew C. - Chandrasegaran, Praveena - Lestari, Agatha Nabilla - Heslop, Rhiannon - Cheaib, Bachar - Ogunsola, John - Ngoyi, Dieudonne Mumba - Kuispond Swar, Nono-Raymond - Cooper, Anneli - Mabbott, Neil A. - Coffelt, Seth B. - MacLeod, Annette
γδ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection
Nature Communications, 29 August 2023. doi: 10.5281/zenodo.7677469
Kremer, Jamila - Jahn, Joshua - Klein, Sabrina - Farag, Mina - Borst, Tobias - Karck, Matthias
Early versus Delayed Surgery in Patients with Left-Sided Infective Endocarditis and Stroke
Journal of Cardiovascular Development and Disease, 21 August 2023. doi: 10.3390/jcdd10080356
Schaupp, L. - Addante, A. - Voller, M. - Fentker, K. - Kuppe, A. - Bardua, M. - Duerr, J. - Piehler, L. - Rohmel, J. - Thee, S. - Kirchner, M. - Ziehm, M. - Lauster, D. - Haag, R. - Gradzielski, M. - Stahl, M. - Mertins, P. - Boutin, S. - Graeber, S. Y. - Mall, M. A.
Longitudinal Effects of Elexacaftor/Tezacaftor/Ivacaftor on Sputum Viscoelastic Properties, Airway Infection and Inflammation in Patients with Cystic Fibrosis
The European respiratory journal, 08 August 2023. doi: 10.1183/13993003.02153-2022
A A Mardiko - J Buer - A M Köster - H E J Kaba - F Mattner - J Zweigner - N T Mutters - N von Maltzahn - R Leistner - T Eckmanns -
C Brandt - S Scheithauer
Infection prevention and control between legal requirements and German Society for Hygiene and Microbiology expert assessments: a cross-sectional study in September-November 2022
J Hosp Infect, July 2023. doi: 10.1016/j.jhin.2023.04.001
Seebach, E. - Kraus, F. V. - Elschner, T. - Kubatzky, K. F.
Staphylococci planktonic and biofilm environments differentially affect osteoclast formation
Inlammation Research, 17 June 2023. doi: 10.1007/s00011-023-01745-9
Seebach, E. - Elschner, T. - Kraus, F. V. - Souto-Carneiro, M. - Kubatzky, K. F.
Bacterial and Metabolic Factors of Staphylococcal Planktonic and Biofilm Environments Differentially Regulate Macrophage Immune Activation
Inflammation, 22 May 2023. doi: 10.1007/s10753-023-01824-3
Anderson, A. C. - von Ohle, C. - Frese, C. - Boutin, S. - Bridson, C. - Schoilew, K. - Peikert, S. A. - Hellwig, E. - Pelz, K. - Wittmer A. - Wolff, D. - Al-Ahmad, A.
The oral microbiota is a reservoir for antimicrobial resistance: resistome and phenotypic resistance characteristics of oral biofilm in health, caries, and periodontitis
Annals of Clinical Microbiology and Antimicrobials, 13 May 2023. doi: 10.1186/s12941-023-00585-z
Dubler, S. - Etringer, M. - Weigand, M. A. - Brenner, T. - Zimmermann, S. - Schnitzler, P. - Budeus, B. - Rengier, F. - Kalinowska, P. - Hoo, Y. L. - Lichtenstern, C.
Impact of Invasive Pulmonary Aspergillosis in Critically Ill Surgical Patients with or without Solid Organ Transplantation
Journal of clinical medicine, 4 May 2023. doi: 10.3390/jcm12093282
Kaan Kocer - Deniz Boudour-Halil - Quan Chanthalangsy - Aline Sähr - Klaus Heeg - Sébastien Boutin - Dennis Nurjadi
Genomic Modification of TonB and Emergence of Small-Colony Phenotype in VIM- and NDM-Producing Escherichia coli following Cefiderocol Exposure In Vitro
Antimicrobial Agents and Chemotherapy, 06 April 2023. doi: 10.1128/aac.00118-23
Lou, D. - Meurer, M. - Ovchinnikova, S. - Burk, R. - Denzler, A. - Herbst, K. - Papaioannou, I. A. - Duan, Y. - Jacobs, M. L. - Witte, V. - Ürge, D. - Kirrmaier, D. - Krogemann, M. - Gubicza, K. - Boerner, K. - Bundschuh, C. - Weidner, N. M. - Merle, U. - Knorr, B. - Welker, A. - Denkinger, C. M. - Schnitzler, P. - Kräusslich, H. G. - Dao Thi, V. L. - De Allegri, M. - Nguyen, H. T. - Deckert, A. - Anders, S. - Knop, M.
Scalable RT-LAMP-based SARS-CoV-2 testing for infection surveillance with applications in pandemic preparedness
EMBO Rep, 23 March 2023, doi: 10.15252/embr.202357162
Jochen Kurz- Lothar Erdinger
A novel route to estimate the photocatalytic activity of titanium dioxide via voltage measurements
Photochem Photobiol Sci, 22 March 2023. doi: 10.1007/s43630-022-00337-6
Sushmita Chakraborty - Jakob Schneider - Dipendra Kumar Mitra - Katharina F. Kubatzky
Mechanistic insight of Interleukin-9 induced osteoclastogenesis
Immunology. 02 Feb 2023. doi: 10.1111/imm.13630
Björn Helm - Michael Geissler - Robin Mayer - Sara Schubert - Reinhard Oertel - Roger Dumke - Alexander Dalpke - Ali El-Armouche - Bertold Renner - Peter Krebs
Regional and temporal differences in the relation between SARS-CoV-2 biomarkers in wastewater and estimated infection prevalence – Insights from long-term surveillance
Sci Total Environ, 20 January 2023. doi: 10.1016/j.scitotenv.2022.159358
Sushmita Chakraborty - Bianca Handrick - Dayoung Yu - Konrad A. Bode - Anna Hafner - Judith Schenz -
Dominik Schaack - Florian Uhle - Taro Tachibana - Shigeki Kamitani - Thomas Vogl - Katharina F. Kubatzky
Gαq modulates the energy metabolism of osteoclasts
Front. Cell. Infect. Microbiol., 09 January 2023. doi: 10.3389/fcimb.2022.1016299
Publikationen 2022
Jochen Kurz, Lothar Erdinger
A novel route to estimate the photocatalytic activity of titanium dioxide via voltage measurements
Photochemical & Photobiological Sciences, 19 November 2023. doi: 10.1007/s43630-022-00337-6
Aktuelles Highlight der Infektionsprävention und Klin. Mikrobiologie
Kaan Kocer, Sébastien Boutin, Klaus Heeg, Dennis Nurjadi
The acquisition of transferable extrachromosomal fec operon is associated with a cefiderocol MIC increase in Enterobacterales
Journal of Antimicrobial Chemotherapy, 77(12). doi: 10.1093/jac/dkac347
Katharina F. Kubatzky
Pasteurella multocida toxin – lessons learned from a mitogenic toxin
Frontiers in Immunology 2022, 13. doi: 10.3389/fimmu.2022.1058905
Chiriac U, Rau H, Frey OR, Röhr AC, Klein S, Meyer AL, Morath B. 2022
Validation and Application of an HPLC-UV Method for Routine Therapeutic Drug Monitoring of Dalbavancin.
Antibiotics 2022, 11(5). doi: 10.3390/antibiotics11050541.
Dumke R, Geissler M, Skupin A, Helm B, Mayer R, Schubert S, Oertel R, Renner B, Dalpke AH. 2022
Simultaneous Detection of SARS-CoV-2 and Influenza Virus in Wastewater of Two Cities in Southeastern Germany, January to May 2022.
Int J Environ Res Public Health 2022, 19(20). doi: 10.3390/ijerph192013374.
Frey DL, Bridson C, Dittrich S, Graeber SY, Stahl M, Wege S, Herth F, Sommerburg O, Schultz C, Dalpke A, Mall M, Boutin S. 2022
Changes in microbiome dominance are associated with declining lung function and fluctuating inflammation in people with Cystic Fibrosis.
Front Microbiol, 13:885822 doi: 10.3389/fmicb.2022.885822
Hildebrand D, Böhringer J, Körner E, Chiriac U, Förmer S, Sähr A, Hoppe-Tichy T, Heeg K, Nurjadi D. 2022
Cefiderocol Protects against Cytokine- and Endotoxin-Induced Disruption of Vascular Endothelial Cell Integrity in an In Vitro Experimental Model.
Antibiotics 2022, 11(5). doi: 10.3390/antibiotics11050581.
Hildebrand D, Nurjadi D, Hoan NX, Linh MTH, Sang VV, Bang MH, Pallerla SR, Kremsner PG, Heeg K, Song LH et al. 2022
Association Between Soluble Notch Ligand Delta-like Ligand 1 and Bleeding Complications in Patients With Dengue Fever Infection.
J Infect Dis 2022, 225(3):476-480. doi: 10.1093/infdis/jiab404
Klein S, Boutin S, Kocer K, Fiedler MO, Storzinger D, Weigand MA, Tan B, Richter D, Rupp C, Mieth M et al. 2022
Rapid Development of Cefiderocol Resistance in Carbapenem-resistant Enterobacter cloacae During Therapy Is Associated With Heterogeneous Mutations in the Catecholate Siderophore Receptor cirA.
Clin Infect Dis 2022, 74(5):905-908. doi: 10.1093/cid/ciab511
Manzke J, Stauf R, Neumann B, Molitor E, Hischebeth G, Simon M, Jantsch J, Rödel J, Becker SL, Halfmann A et al. 2022
German Multicenter Study Analyzing Antimicrobial Activity of Ceftazidime-Avibactam of Clinical Meropenem-Resistant Pseudomonas aeruginosa Isolates Using a Commercially Available Broth Microdilution Assay.
Antibiotics 2022, 11(5). doi: 10.3390/antibiotics11050545
Nurjadi D, Kocer K, Chanthalangsy Q, Klein S, Heeg K, Boutin S. 2022
New Delhi Metallo-Beta-Lactamase Facilitates the Emergence of Cefiderocol Resistance in Enterobacter cloacae.
Antimicrob Agents Chemother 2022, 66(2):e0201121. doi: 10.1128/AAC.02011-21
Passaris I, Mauder N, Kostrzewa M, Burckhardt I, Zimmermann S, van Sorge NM, Slotved HC, Desmet S, Ceyssens PJ. 2022
Validation of Fourier Transform Infrared Spectroscopy for Serotyping of Streptococcus pneumoniae.
J Clin Microbiol 2022:e0032522. doi: 10.1128/jcm.00325-22
Louise Benning, Christian Morath, Marie Bartenschlager, Heeyoung Kim, Marvin Reineke, Jörg Beimler,
irabel Buylaert, Christian Nusshag, Florian Kälble, Paula Reichel, Maximilian Töllner, Matthias Schaier,
Katrin Klein, Vladimir Benes, Tobias Rausch, Susanne Rieger, Maximilian Stich, Burkhard Tönshoff,
Niklas Weidner, Paul Schnitzler, Martin Zeier, Caner Süsal, Thuong Hien Tran,
Ralf Bartenschlager, Claudius Speer
Neutralizing antibody response against the B.1.617.2 (delta) and the B.1.1.529 (omicron) variants after a third mRNA SARS-CoV-2 vaccine dose in kidney transplant recipients
American Journal of Transplantation 22 (7), 1873-1883. doi: 10.1111/ajt.17054
Probst K, Boutin S, Spath I, Scherrer M, Henny N, Sahin D, Heininger A, Heeg K, Nurjadi D. 2022
Direct-PCR from rectal swabs and environmental reservoirs: A fast and efficient alternative to detect blaOXA-48 carbapenemase genes in an Enterobacter cloacae outbreak setting.
Environ Res 2022, 203:111808. doi: 10.1016/j.envres.2021.111808
Schirmer B, Giehl K, Kubatzky KF. 2022
Report of the 24th Meeting on Signal Transduction 2021.
Int J Mol Sci 2022, 23(4). doi: 10.3390/ijms23042015
von Dehn F, Mutters NT, Eichel VM, Merle U, Brenner T, Nafe M, Sander A, Wolkewitz M, Frank U. 2022
Effect of didecyl dimethyl ammonium chloride-impregnated washcloth wipe whole-body bathing on catheter-related blood stream infections and central venous line-associated infections in adult intensive care units.
Clin Microbiol Infect 2022, 28(4):564-569. doi: 10.1016/j.cmi.2021.07.029
Yadav AM, Bagade MM, Ghumnani S, Raman S, Saha B, Kubatzky KF, Ashma R. 2022
The phytochemical plumbagin reciprocally modulates osteoblasts and osteoclasts.
Biol Chem 2022, 403(2):211-229. doi: 10.1515/hsz-2021-0290
Publikationen 2021
Baumgartl T, Petzold M, Wunderlich M, Hohn M, Archambault D, Lieser M, Dalpke A, Scheithauer S, Marschollek M, Eichel VM et al. 2021
In Search of Patient Zero: Visual Analytics of Pathogen Transmission Pathways in Hospitals.
IEEE Trans Vis Comput Graph 2021, 27(2):711-721. doi: 10.1109/TVCG.2020.3030437
Boutin S, Hildebrand D, Boulant S, Kreuter M, Ruter J, Pallerla SR, Velavan TP, Nurjadi D. 2021
Host factors facilitating SARS-CoV-2 virus infection and replication in the lungs.
Cell Mol Life Sci 2021, 78(16):5953-5976. doi: 10.1007/s00018-021-03889-5
Culbreath K, Piwonka H, Korver J, Noorbakhsh M. 2021
Benefits Derived from Full Laboratory Automation in Microbiology: a Tale of Four Laboratories.
J Clin Microbiol 2021, 59(3). doi: 10.1128/JCM.01969-20
Constantinos Tsioutis, Vanessa M Eichel, Nico T Mutters. 2021
Transmission of Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae: the role of infection control.
Journal of Antimicrobial Chemotherapy, Volume 76, Issue Supplement_1, January 2021, Pages i4–i11, https://doi.org/10.1093/jac/dkaa492
Eichel VM, Boutin S, Frank U, Weigand MA, Heininger A, Mutters NT, Buchler MW, Heeg K, Nurjadi D. 2021
Impact of discontinuing contact precautions and enforcement of basic hygiene measures on nosocomial vancomycin-resistant Enterococcus faecium transmission.
J Hosp Infect 2021, 121:120-127. doi: 10.1016/j.jhin.2021.11.020
Freischmidt H, Armbruster J, Bonner E, Guehring T, Nurjadi D, Bechberger M, Sonntag R, Schmidmaier G, Grutzner PA, Helbig L. 2021
Systemic Administration of PTH Supports Vascularization in Segmental Bone Defects Filled with Ceramic-Based Bone Graft Substitute.
Cells 2021, 10(8). doi: 10.3390/cells10082058
Frey DL, Boutin S, Dittrich SA, Graeber SY, Stahl M, Wege S, Herth FJF, Sommerburg O, Schultz C, Mall MA, Dalpke AH. 2020
Relationship between airway dysbiosis, inflammation and lung function in adults with cystic fibrosis.
J Cyst Fibros. 2021 Jan 8:S1569-1993(20)30954-1.
Hildebrand D, Nurjadi D, Hoan NX, Linh MTH, Sang VV, Bang MH, Pallerla SR, Kremsner PG, Heeg K, Song LH, Velavan TP. 2021
Soluble Notch ligand DLL1 is associated with bleeding complication in patients with dengue fever infection
J. Infect. Dis., 2021;, jiab404, doi: 10.1093/infdis/jiab404
Jasuja JK, Zimmermann S, Burckhardt I. 2021
Applicability and performance of EUCAST's rapid antimicrobial susceptibility testing (RAST) on primarily sterile body fluids in blood culture bottles in laboratory routine with total lab automation.
Eur J Clin Microbiol Infect Dis 2021, 40(6):1217-1225. doi: 10.1007/s10096-020-04146-6
Klein EM, Sauer S, Klein S, Tichy D, Benner A, Bertsch U, Brandt J, Kimmich C, Goldschmidt H, Muller-Tidow C et al. 2021
Antibiotic Prophylaxis or Granulocyte-Colony Stimulating Factor Support in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation.
Cancers (Basel) 2021, 13(14). doi: 10.3390/cancers13143439
Klein S, Boutin S, Heeg K, Zanger P, Nurjadi D. 2021
Genomic Structure of ST8-t008 USA300 and USA300-LV MRSA in the Rhine- Neckar Region, Germany, 2012-2018.
Int J Antimicrob Agents. 2021 Feb 23:106312. doi: 10.1016/j.ijantimicag.2021.106312.
Klein S, Boutin S, Kocer K, Fiedler MO, Storzinger D, Weigand MA, Tan B, Richter D, Rupp C, Mieth M et al. 2021
Rapid development of cefiderocol resistance in carbapenem-resistant Enterobacter cloacae during therapy is associated with heterogeneous mutations in the catecholate siderophore receptor cira.
Clin Infect Dis 2021. doi: 10.1093/cid/ciab511
Klein S, Boutin S, Spath I, Kimmich C, Brandt J, Muller-Tidow C, Heeg K, Nurjadi D. 2021
Acquisition and Transmission of Carbapenemase-Producing (blaKPC-2) Enterobacter cloacae in a Highly Frequented Outpatient Clinic.
Clin Infect Dis 2021, 72(5):e158-e161. doi: 10.1093/cid/ciaa1734
Kocer K, Klein S, Hildebrand D, Krall J, Heeg K, Boutin S, Nurjadi D. 2021
Pitfalls in genotypic antimicrobial susceptibility testing caused by low expression of blaKPC in Escherichia coli.
J Antimicrob Chemother 2021. doi: 10.1093/jac/dkab267
Krall LJ, Klein S, Boutin S, Wu CC, Sahr A, Stanifer ML, Boulant S, Heeg K, Nurjadi D, Hildebrand D. 2021
Invasiveness of Escherichia coli Is Associated with an IncFII Plasmid.
Pathogens 2021, 10(12). doi: 10.3390/pathogens10121645
Lemke C, Benysek J, Brajtenbach D, Breuer C, Jilkova A, Horn M, Busa M, Ulrychova L, Illies A, Kubatzky KF et al. 2021
An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity.
J Med Chem 2021, 64(18):13793-13806. doi: 10.1021/acs.jmedchem.1c01178
Moll M, Reichel K, Nurjadi D, Förmer S, Krall LJ, Heeg K, Hildebrand D. 2021
Notch Ligand Delta-Like 1 Is Associated With Loss of Vascular Endothelial Barrier Function.
Frontiers in Physiology 2021, 12 doi: 10.3389/fphys.2021.766713
Nair A, Kubatzky KF, Saha B. 2021
Ras Isoforms from Lab Benches to Lives-What Are We Missing and How Far Are We?
Int J Mol Sci 2021, 22(12). doi: 10.3390/ijms22126508
Nurjadi D, Chanthalangsy Q, Zizmann E, Stuermer V, Moll M, Klein S, Boutin S, Heeg K, Zanger P. 2021
Phenotypic Detection of Hemin-Inducible Trimethoprim-Sulfamethoxazole Heteroresistance in Staphylococcus aureus.
Microbiol Spectr 2021, 9(2):e0151021. doi: 10.1128/Spectrum.01510-21
Nurjadi D, Eichel VM, Tabatabai P, Klein S, Last K, Mutters NT, Poschl J, Zanger P, Heeg K, Boutin S. 2021
Surveillance for Colonization, Transmission, and Infection With Methicillin-Susceptible Staphylococcus aureus in a Neonatal Intensive Care Unit.
JAMA Netw Open 2021, 4(9):e2124938. doi: 10.1001/jamanetworkopen.2021.24938
Nurjadi D, Klein S, Hannesen J, Heeg K, Boutin S, Zanger P. 2021
Molecular analysis of an increase in trimethoprim/sulfamethoxazole-resistant MRSA reveals multiple introductions into a tertiary care hospital, Germany 2012-19.
J Antimicrob Chemother 2021. doi: 10.1093/jac/dkab341
Nurjadi D, Kocer K, Chanthalangsy Q, Klein S, Heeg K, Boutin S. 2021
New Delhi metallo-beta-lactamase facilitates the emergence of cefiderocol resistance in Enterobacter cloacae. Antimicrob Agents Chemother
2021:AAC0201121. doi: 10.1128/AAC.02011-21
Nurjadi D, Ruhparwar A, Zanger P. 2021
Existing evidence supports clinical trials on interventions preventing ventricular assist device infection in patients colonized with Staphylococcus aureus. Letter regarding the article 'Association of preoperative infections, nasal Staphylococcus aureus colonization and gut microbiota with left ventricular assist device outcomes'. br /> Eur J Heart Fail 2021, 23(9):1566. doi: 10.1002/ejhf.2260
Nurjadi D, Scherrer M, Frank U, Mutters NT, Heininger A, Spath I, Eichel VM, Jabs J, Probst K, Muller-Tidow C, Brandt J, Heeg K, Boutin S. 2021
Genomic Investigation and Successful Containment of an Intermittent Common Source Outbreak of OXA-48-Producing Enterobacter cloacae Related to Hospital Shower Drains.
Microbiol Spectr 2021:e0138021. doi: 10.1128/Spectrum.01380-21
Nurjadi D, Zizmann E, Chanthalangsy Q, Heeg K, Boutin S. 2021
Integrative Analysis of Whole Genome Sequencing and Phenotypic Resistance Toward Prediction of Trimethoprim-Sulfamethoxazole Resistance in Staphylococcus aureus.
Front Micrbiol 11:607842. doi: 10.3389/fmicb.2020.607842
Probst K, Boutin S, Spath I, Scherrer M, Henny N, Sahin D, Heininger A, Heeg K, Nurjadi D. 2021
Direct-PCR from rectal swabs and environmental reservoirs: A fast and efficient alternative to detect blaOXA-48 carbapenemase genes in an Enterobacter cloacae outbreak setting.
Environ Res 2021, 203:111808. doi: 10.1016/j.envres.2021.111808
Probst K, Nurjadi D, Heeg K, Frede AM, Dalpke AH, Boutin S. 2021
Molecular Detection of Carbapenemases in Enterobacterales: A Comparison of Real-Time Multiplex PCR and Whole-Genome Sequencing.
Antibiotics (Basel) 2021, 10(6). doi: 10.3390/antibiotics10060726
Richter DC, Dietrich M, Lalev LD, Schmitt FCF, Fiedler MO, Bruckner T, Stoerzinger D, Chiriac U, Klein S, Hackert T et al. 2021
Prolonged Infusion of beta-Lactams Decreases Mortality in Patients with Septic Shock: A Retrospective before-and-after Study.
Antibiotics (Basel) 2021, 10(6). doi: 10.3390/antibiotics10060687
Son TV, Manh ND, Trung NT, Quyen DT, Meyer CG, Phuong NTK, Hoan PQ, Sang VV, Nurjadi D, Velavan TP et al. 2021
Molecular detection of blaCTX-M gene to predict phenotypic cephalosporin resistance and clinical outcome of Escherichia coli bloodstream infections in Vietnam.
Ann Clin Microbiol Antimicrob 2021, 20(1):60. doi: 10.1186/s12941-021-00466-3
Sultanli S, Ghumnani S, Ashma R, Kubatzky KF.2021
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Int J Mol Sci. 2021 Mar 9;22(5):2779. doi: 10.3390/ijms22052779.PMID: 33803472
Tanner MC, Heller RA, Grimm A, Zimmermann S, Pilz M, Jurytko L, Miska M, Helbig L, Schmidmaier G, Haubruck P. 2021
The Influence of an Occult Infection on the Outcome of Autologous Bone Grafting During Surgical Bone Reconstruction: A Large Single-Center Case-Control Study.
J Inflamm Res 2021, 14:995-1005. doi: 10.2147/JIR.S297329
Tschudin-Sutter S, Lavigne T, Grundmann H, Rauch J, Eichel VM, Deboscker S, Jaulhac B, Mutters NT. 2021
Differences in infection control and diagnostic measures for multidrug-resistant organisms in the tristate area of France, Germany and Switzerland in 2019 - survey results from the RH(E)IN-CARE network.
Swiss Med Wkly. 2021 Mar 1;151:w20454. doi: 10.4414/smw.2021.20454. PMID: 33705560.
Tsioutis C, Eichel VM, Mutters NT. 2021
Transmission of Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae: the role of infection control.
J Antimicrob Chemother 2021, 76(Suppl 1):i4-i11. doi: 10.1093/jac/dkaa492
Viet NT, Van Du V, Thuan ND, Van Tong H, Toan NL, Van Mao C, Van Tuan N, Pallerla SR, Nurjadi D, Velavan TP et al. 2021
Maternal Vaginal Colonization and Extended-Spectrum Beta-Lactamase-Producing Bacteria in Vietnamese Pregnant Women.
Antibiotics (Basel) 2021, 10(5). doi: 10.3390/antibiotics10050572
Yadav AM, Bagade MM, Ghumnani S, Raman S, Saha B, Kubatzky KF, Ashma R. 2021
The phytochemical plumbagin reciprocally modulates osteoblasts and osteoclasts.
Biol Chem 2022, 403(2):211-229. doi: 10.1515/hsz-2021-0290
Publikationen 2020
Armstrong C, Kuhn CT, Dufner M, Ehlermann P, Zimmermann S, Lichtenstern C, Soethoff J, Katus HA, Leuschner F, Heininger A. 2020
The diagnostic benefit of 16S rDNA PCR examination of infective endocarditis heart valves: a cohort study of 146 surgical casesconfirmed by histopathology
Clin Res Card. 2020. doi: 10.1007/s00392-020-01678-x
Boutin S, Dalpke AH. 2020
The Microbiome: A Reservoir to Discover New Antimicrobials Agents.
Curr Top Med Chem. 2020;20(14):1291-1299.
Campos ACDC, Andrade NL, Couto N, Mutters NT, de Vos M, Rosa ACP, Damasco PV, Lo Ten Foe JR, Friedrich AW, Chlebowicz-Flissikowska MA, Rossen JWA. 2020
Characterization of fosfomycin heteroresistance among multidrug-resistant Escherichia coli isolates from hospitalized patients in Rio de Janeiro, Brazil.
J Glob Antimicrob Resist. 2020 May 7;22:584-593. doi: 10.1016/j.jgar.2020.04.026. Online ahead of print.
Decker AO, Hildebrand D, Bruckner T, Lichtenstern C, Heeg K, Weigand M, Brenner T, Uhle F. 2020
Delta-Like Canonical Notch Ligand 1 in Patients Following Liver Transplantation—A Secondary Analysis of a Prospective Cohort Study
Diagnostics 2020, 10, 894. doi: 10.3390/diagnostics10110894
Decker AO, Incamps A, Sigl A, Uhle F, Bruckner T, Heininger A, Zimmermann S, Hirtz C, Weigans MA, Brenner T. 2020
Soluble Intercellular Adhesion Molecule- (sICAM-) 1, Thrombospondin-1, and Vinculin for the Identification of Septic Shock Patients Suffering from an Invasive Fungal Infection
Mediators of Inflammation. 2020; 3470163:13. doi: 10.1155/2020/3470163
Dubler S, Lenz M, Zimmermann S, Richter DC, Weiss KH, Mehrabi A, Mieht M, Bruckner T, Weigand MA, Brenner T, Heininger A. 2020
Does vancomycin resistance increase mortality in Enterococcus faecium bacteraemia after orthotopic liver transplantation? A retrospective study
Anti Res Inf Cont. 2020; 9(22). doi: 10.1186/s13756-020-0683-3
Eichel V, Klein S, Bootsveld C, Frank U, Heeg K, Boutin S, Nurjadi D. 2020
Challenges in interpretation of WGS and epidemiological data toinvestigate nosocomial transmission of vancomycin-resistantEnterococcus faeciumin an endemic region: incorporation of patientmovement network and admission screening
J Antimicrob Chemother, 2020 May 15;dkaa122. Online ahead of print. doi: 10.1093/jac/dkaa122
Eichel V, Papan C, Boutin S, Pöschl J, Heeg K, Nurjadi D.
Altering Antibiotic Regimen as Additional Control Measure in Suspected Multi-Drug-Resistant Enterobacter cloacae Outbreak in a Neonatal Intensive Care Unit.
J Hosp Infect. 2020 Feb;104(2):144-149. doi: 10.1016/j.jhin.2019.09.007. Epub 2019 Sep 13. PMID: 31525448.
Eichel V, Schüller A, Al-Ahmad A, Frank U. 2020
Antimicrobial effects of mustard oil-containing plants against oral pathogens: an in vitro study
BMC Complementary Medicine and Therapies2020; 20(156). doi: 10.1186/s12906-020-02953-0
Frank U, Eichel V. 2020
Hygiene in der Portpflege in Portpflege: Hygiene, Verbandswechsel, Überwachung, Komplikationsmanagement.
Roland Hennes, Gisela Müller. Springer Berlin Heidelberg 2020.
Günther SK, Geiss C, Kaiser SJ, Mutters NT, Günther F. Transfus Med Hemother. 2020
Microbiological Control of Cellular Products: The Relevance of the Cellular Matrix, Incubation Temperature, and Atmosphere for the Detection Performance of Automated Culture Systems.
Transfus Med Hemother. 2020 Jun;47(3):254-263. doi: 10.1159/000503397. Epub 2019 Oct 22.
Heininger A, Zimmermann S, Bootsveld C, Boutin S, Nurjadi D. 2020
Low prevalence of combined linezolid- and vancomycin-resistant Enterococcus faecium from hospital admission screening in an endemic region in Germany
JGAR 2020. doi: 10.1016/j.jgar.2020.05.003
Helbig L, Guehring T, Titze N, Nurjadi D, Sonntag R, Armbruster J, Wildemann B, Schmidmaier G, Gruetzner AP, Freischmidt H. 2020
A new sequential animal model for infection-related non-unions with segmental bone defect
BMC Musculoskelet Disord 21, 329 (2020). doi: 10.1186/s12891-020-03355-6
Herster F, Bittner Z, Archer NK, Dickhöfer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Löffler MW, Kalbacher H, Vierbuchen T, Heine H, Miller LS, Hartl D, Freund L, Schäkel K, Heister M, Ghoreschi K, Weber ANR. 2020
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.
Nat Commun. 2020 Jan 8;11(1):105. doi: 10.1038/s41467-019-13756-4.
Horvath L, Hanselmann S, Mannsperger H, Degenhardt S, Last K, Zimmermann ;S, Burckhardt I. 2021
Machine-assisted interpretation of auramine stains substantially increases through-put and sensitivity of microscopic tuberculosis diagnosis
Tuberculosis (Edinb). 2020 Dec;125:101993. doi: 10.1016/j.tube.2020.101993. Epub 2020 Sep 19.
Jasuja JK, Zimmermann S, Burckhardt I. 2020
Evaluation of EUCAST rapid antimicrobial susceptibility testing (RAST) for positive blood cultures in clinical practice using a total lab automation.
Eur J Clin Microbiol Infect Dis (2020). doi: 10.1007/s10096-020-03846-3
Klein S, Boutin S, Späth I, Kimmich C, Brandt J, Carsten MT, Heeg K, Nurjadi D.
Acquisition and transmission of carbapenemase producing (blaKPC-2) Enterobacter cloacae in a highly frequented outpatient clinic.
Clin Infect Dis. 2020 Nov 19:ciaa1734.
Klein S, Hannesen J, Zanger P, Heeg K, Boutin S, Nurjadi D. 2020
Entry of Panton-Valentine leukocidin-positive methicilin-resistant Staphylococcus aureus into the hospital: prevalence and population structure in Heidelberg, Germany 2015-2018
Sci Rep 10, 13243 (2020). doi: 10.1038/s41598-020-70112-z
Kocer K, Boutin S, Probst K, Heeg K, Nurjadi D. 2020
Whole-genome sequencing disproves two suspected transmission events of blaNDM between Pseudomonas aeruginosa and Enterobacterales in hospitalized patients
J Hosp Infect. 106, 2, 2020. doi: 10.1016/j.jhin.2020.07.006.
Kolbe U, Yi B, Poth T, Saunders A, Boutin S, Dalpke AH.
Early Cytokine Induction Upon Pseudomonas aeruginosa Infection in Murine Precision Cut Lung Slices Depends on Sensing of Bacterial Viability.
Front Immunol. 2020 Oct 30;11:598636.
Masson C, Birgand G, Castro-Sánchez E, Eichel VM, Comte A, Terrisse H, Rubens-Duval B, Gillois P, Albaladejo P, Picard J, Bosson JL, Mutters NT, Landelle C. 2020
Is virtual reality effective to teach prevention of surgical site infections in the operating room? study protocol for a randomised controlled multicentre trial entitled VIP Room study.
BMJ Open. 2020 Jun 21;10(6):e037299. doi: 10.1136/bmjopen-2020-037299.
Mühlberg E, Umstätter F, Domhan C, Hertlein T, Ohlsen K, Krause, Kleist C, Beijer B, Zimmermann S, Haberkorn W, Mier W, Uhl P. 2020
Vancomycin-Lipopeptide Conjugates with High Antimicrobial Activity on Vancomycin-Resistant Enterococci.
Pharmaceuticals. 2020; 13(110). doi: 10.3390/ph13060110
Müller M, Petzold M, Wunderlich M, Baumgartl T, Höhn M, Eichel V, N. Mutters, S. Scheithauer, M. Marschollek, T. von Landesberger. 2020
Visual Analysis for Hospital Infection Control using a RNN Model.
EuroVis Workshop on Visual Analytics 2020
Nurjadi D, Boutin S, Schmidt K, Ahmels M, Hasche D. 2020
Identification and Elimination of the Clinically Relevant Multi-Resistant Environmental Bacteria Ralstonia insidiosa in Primary Cell Culture.
Microorganisms. 2020 Oct 17;8(10):1599.
Nurjadi D, Last K, Klein S, Boutin S, Schmack B, Mueller F, Heeg K, Ruhpawar A, Heininger A, Zanger P. 2020
Nasal colonization with Staphylococcus aureus is a risk factor for ventricular assist device infection in the first year after implantation: A prospective, single-centre, cohort study.
J Infect. 80 (2020). doi: 10.1016/j.jinf.2020.02.015
Schirmer B, Giehl K, Kubatzky KF.
Report of the 23rd Meeting on Signal Transduction 2019-Trends in Cancer and Infection.
Int J Mol Sci. 2020 Apr 15;21(8):2728. doi: 10.3390/ijms21082728.
Schmitt FCF, Lipinski A, Hofer S, Uhle F, Nusshag C, Hackert T, Dalpke AH, Weigand MA, Brenner T, Boutin S. 2020
Pulmonary microbiome patterns correlate with the course of the disease in patients with sepsis-induced ARDS following major abdominal surgery.
J Hosp Infect. 2020 Apr 24:S0195-6701(20)30203-6.
Sörensen M, Kantorek J, Byrnes L, Boutin S, Mall MA, Lasitschka F, Zabeck H, Nguyen D, Dalpke AH.
Pseudomonas aeruginosa Modulates the Antiviral Response of Bronchial Epithelial Cells.
Front Immunol. 2020 Feb 4;11:96.
Sörensen M, Khakimov B, Nurjadi D, Boutin S, Yi B, Dalpke AH, Eigenbrod T.
Comparative evaluation of the effect of different growth media on in vitro sensitivity to azithromycin in multi-drug resistant Pseudomonas aeruginosa isolated from cystic fibrosis patients.
Antimicrob Resist Infect Control. 2020 Dec 9;9(1):197.
Umstätter F, Domhan C, Hertlein T, Ohlsen K, Mühlberg E, Kleist C, Zimmermann S, Beijer B, Klika DK, Haberkron U, Mier W, Uhl P. 2020
Vancomycin Resistance is Overcome by Conjugation of Polycationic Peptides.
Angew. Chem. Int Ed. 2020June 22; 59(23): 8823-8827. doi: 10.1002/anie.202002727
Welker S, Boutin S, Miethke T, Heeg K, Nurjadi D. 2020.
Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla OXA-244 in Germany, 2019 to 2020.
Euro Surveill. 2020 Nov;25(46):2001815.
Zimmermann S, Horner S, Altwegg M, Dalpke AH. 2020
Workflow optimization for syndromic diarrhea diagnosis using the molecular Seegene Allplex™ GI-Bacteria(I) assay
Eur J Clin Microbiol Infect Dis. 2020. doi: 10.1007/s10096-020-03837-4
Publikationen 2019
Braun MS, Wang E, Zimmermann S, Boutin S, Wagner H, Wink M. 2019
Kocuria tytonis sp. nov., isolated from the uropygial gland of an American barn owl (Tyto furcata).
Int J Syst Evol Microbiol. 2019 Feb;69(2):447-451. doi: 10.1099/ijsem.0.003170.
Braun MS, Wang E, Zimmermann S, Boutin S, Wagner H, Wink M. 2019
Kocuria tytonicola, new bacteria from the preen glands of American barn owls (Tyto furcata)
Systematic and Applied Microbiology 2019;42,2:198-204. doi: 10.1016/j.syapm.2018.11.004
Buchholz U, Dullin J, Lück C, Petzold A, Petzold M, Berges M, Exner M, Jahn HJ, Lachmann R, Brodhun B, Lelgemann M. 2019
Ausbruch ambulant erworbener Legionellosen in Bremen 2015 und 2016 – Erfahrungen, Ergebnisse, Entscheidungen.
Epid Bull 2019;28:251-257. doi: 10.25646/6199
Burckhardt I. 2019
Laboratory Automation in Clinical Microbiology.
Bioengineering (Basel). 2018 Nov 22;5(4). pii: E102. doi: 10.3390/bioengineering5040102.
Burckhardt I. 2019
Laborautomation in der Mikrobiologie - Zu einer schnelleren und besseren individualisierten Diagnostik
Biospektrum (2019) 25: 620. doi: 10.1007/s12268-019-0204-1
Burckhardt I, Last K, Zimmermann S. 2019.
Shorter Incubation Times for Detecting Multi-drug Resistant Bacteria in Patient Samples: Defining Early Imaging Time Points Using Growth Kinetics and Total Laboratory Automation
Ann Lab Med 2019;39:43-49. doi: 10.3343/alm.2019.39.1.43
Burckhardt I, Sebastian K, Mauder N, Kostrzewa M, Burckhardt F, Zimmermann S. 2019
Analysis of Streptococcus pneumoniae using Fourier-transformed infrared spectroscopy allows prediction of capsular serotype.
Eur J Clin Microbiol Infect Dis. 2019 Oct;38(10):1883-1890. doi: 10.1007/s10096-019-03622-y. Epub 2019 Jul 9.
Chakraborty S, Kubatzky KF, Mitra DK. 2019
An Update on Interleukin-9: From Its Cellular Source and Signal Transduction to Its Role in Immunopathogenesis
Int. J. Mol. Sci. 2019, 20, 2113. doi: 10.3390/ijms20092113
Eichel V, Papan C, Boutin S, Pöschl J, Heeg K, Nurjadi D. 2019
Alteration of antibiotic regimen as an additional control measure in suspected multi-drug-resistant Enterobacter cloacae outbreak in a neonatal intensive care unit.
J Hosp Infect. 2019 Sep 13. pii: S0195-6701(19)30388-3. doi: 10.1016/j.jhin.2019.09.007.
Eichel V, Papan C, Mutters NT. 2019
Update Hygiene: Prevention of Vascular Catheter-Associated Infections in Premature and Newborn Infants
Klin Padiatr. 2019 Jul;231(4):177-182. doi: 10.1055/a-0883-5350. Epub 2019 Apr 11.
Eigenbrod T, Reuter S, Gross A, Kocer K, Günther F, Zimmermann S, Heeg K, Mutters NT, Nurjadi D. 2019
Molecular characterization of carbapenem-resistant Acinetobacter baumannii using WGS revealed missed transmission events in Germany from 2012-15.
J Antimicrob Chemother. 2019 Dec 1;74(12):3473-3480. doi: 10.1093/jac/dkz360.
Einarsson GG, Boutin S. 2019
Techniques: culture, identification and 16S rRNA gene sequencing.
Cox MJ, Ege MJ, von Mutius E, eds. The Lung Microbiome (ERS Monograph). Sheffield, European Respiratory Society. 2019; pp. 18–34 doi: 10.1183/2312508X.10000819
Freund I, Buhl DK, Boutin S, Kotter A, Pichot F, Marchand V, Vierbuchen T, Heine H, Motorin Y, Helm M, Dalpke AH, Eigenbrod T. 2019
2′-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms
RNA 2019. 25: 869-880 doi: 10.1261/rna.070243.118
Freund I, Eigenbrod T, Helm M, Dalpke AH. 2019
RNA Modifications Modulate Activation of Innate Toll-Like Receptors
Genes 2019, 10, 92. doi: 10.3390/genes10020092
Giesbrecht K, Förmer S, Sähr A, Heeg K, Hildebrand D. 2019
Streptococcal Pyrogenic Exotoxin A-Stimulated Monocytes Mediate Regulatory T-Cell Accumulation through PD-L1 and Kynurenine.
Int J Mol Sci. 2019 Aug 13;20(16). doi: 10.3390/ijms20163933
Günther SK, Geiss C, Kaiser SJ, Muters NT, Günther F. 2019
Microbiological Control of Cellular Products: The Relevance of the Cellular Matrix, Incubation Temperature, and Atmosphere for the Detection Performance of Automated Culture Systems
Transfus Med Hemother 2019. doi: 10.1159/000503397
Hafner A, Kolbe U, Freund I, Castiglia V, Kovarik P, Poth T, Herster F, Weigand MA, Weber ANR, Dalpke AH, Eigenbrod T. 2019
Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo
Front. Immunol. 10:198. doi: 10.3389/fimmu.2019.00198
Hildebrand D, Decker SO, Koch C, Schmitt FCF, Ruhrmann S, Schneck E, Sander M, Weigand MA, Brenner T, Heeg K, Uhle F. 2019
Host-Derived Delta-Like Canonical Notch Ligand 1 as a Novel Diagnostic Biomarker for Bacterial Sepsis—Results From a Combinational Secondary Analysis
Front. Cell. Infect. Microbiol. 9:267 doi: 10.3389/fcimb.2019.00267
Hildebrand D, Metz-Zumaran C, Jaschkowitz G, Heeg K. 2019
Silencing SOCS1 via Liposome-Packed siRNA Sustains TLR4-Ligand Adjuvant
Front. Immunol. 10:1279. doi: 10.3389/fimmu.2019.01279
Hipp M, Burckhardt I. 2019
In vitro activity of newer antimicrobials against penicillin non-susceptible strains of Streptococcus pneumoniae.
Infect Drug Resist. 2019 Jul 1;12:1889-1893. doi: 10.2147/IDR.S202789.
Klein S, Menz MD, Zanger P, Heeg K, Nurjadi D. 2019
Increase in the prevalence of Panton–Valentine leukocidin and clonal shift in community-onset methicillin-resistant Staphylococcus aureus causing skin and soft-tissue infections in the Rhine-Neckar Region, Germany, 2012–2016
International Journal of Antimicrobial Agents 53 (2019) 261–267. doi: 10.1016/j.ijantimicag.2018.10.026
Kocer K, Boutin S, Dalpke AH, Heeg K, Mutters NT, Nurjadi D. 2019
Comparative genomic analysis revealed high prevalence of inter-species in vivo transfer of carbapenem resistance plasmids in patients with hematological malignancies.
Clin Microbiol Infect. 2019 Oct 22. pii: S1198-743X(19)30548-8. doi: 10.1016/j.cmi.2019.10.014. [Epub ahead of print] PubMed PMID: 31654794.
Nair A, Chauhan P, Saha B, Kubatzky KF. 2019
Conceptual Evolution of Cell Signaling
Int. J. Mol. Sci. 2019, 20(13), 3292. doi: 10.3390/ijms20133292
Nurjadi D, Fleck R, Lindner A, Schäfer J, Gertler M, Mueller A, Lagler H, Van Genderen PJJ, Caumes E, Kuenzli E, Gascon J, Kantele A, Grobusch MP, Heeg K, Zanger P. 2019
Import of community-associated, methicillin-resistant Staphylococcus aureus to Europe through skin and soft-tissue infection in intercontinental travellers, 2011–2016
Clinical Microbiology and Infection, Volume 25, Issue 6, 2019. doi: 10.1016/j.cmi.2018.09.023
Palusinska-Szysz M, Luchowski R, Gruszecki WI, Choma A, Szuster-Ciesielska A, Lück C, Petzold M, Sroka-Bartnicka A, Kowalczyk B. 2019
The Role of Legionella pneumophila Serogroup 1 Lipopolysaccharide in Host-Pathogen Interaction
Front. Microbiol. 10:2890. doi: 10.3389/fmicb.2019.02890
Schmitt FCF, Brenner T, Uhle F, Loesch F, Hackert T, Ulrich A, Hofer S, Dalpke AH, Weigand MA, Boutin S. 2019
Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery
BMC Microbiology 201919:42 doi: 10.1186/s12866-019-1399-5
Schoilew K, Ueffing H, Dalpke A, Wolff B, Frese C, Wolff D, Boutin S. 2019
Bacterial biofilm composition in healthy subjects with and without caries experience
Journal of Oral Microbiology, 11:1, 1633194. doi: 10.1080/20002297.2019.1633194
Schirmer B, Giehl K, Kubatzky KF. 2019
Report of the Signal Transduction Society Meeting 2018—Signaling: From Past to Future
Int. J. Mol. Sci. 2019, 20(1), 227. doi: 10.3390/ijms20010227
Seebach E, Kubatzky KF. 2019
Chronic Implant-Related Bone Infections—Can Immune Modulation be a Therapeutic Strategy?
Front. Immunol. 10:1724. doi: 10.3389/fimmu.2019.01724
Wolff D, Frese C, Schoilew K, Dalpke A, Wolff B, Boutin S. 2019
Amplicon-based microbiome study highlights the loss of diversity and the establishment of a set of species in patients with dentin caries.
PLoS One. 2019 Jul 31;14(7):e0219714. doi: 10.1371/journal.pone.0219714. eCollection 2019.
Wunderlich M, Block I, Landesberger Tv, Petzold M, Marschollek M, Scheithauer S. 2019
Visual Analysis of Probabilistic Infection Contagion in Hospitals
Vision, Modeling and Visualization. doi: 10.2312/vmv.20191328
Publikationen 2018
AL-Ani I, Zimmermann S, Reichling J and Wink M. 2018
Antimicrobial Activities of European Propolis Collected from Various Geographic Origins Alone and in Combination with Antibiotics.
Medicines 2018, 5, 2 doi: 10.3390/medicines5010002
Boutin S, Weitnauer M, Hassel S, Graeber SY, Stahl M, Dittrich SA, Mall MA and Dalpke AH. 2018
One time quantitative PCR detection of Pseudomonas aeruginosa to discriminate intermittent from chronic infection in Cystic Fibrosis.
J Cyst Fibros. 17(3): 348-355. doi: 10.1016/j.jcf.2017.12.007. [Epub ahead of print]
Braun SM, Sporer F, Zimmermann S, Wink M. 2018.
Birds, feather-degrading bacteria and preen glands: the antimicrobial activity of preen gland secretions from turkeys (Meleagris gallopavo) is amplified by keratinase.
FEMS Microbiology Ecology. fiy117. doi: 10.1093/femsec/fiy117
Braun MS, Wang E, Zimmermann S, Wink M. 2018.
Corynebacterium heidelbergense sp. nov., isolated from the preen glands of Egyptian geese (Alopochen aegyptiacus)
Systematic and Applied Microbiology. pii: S0723-2020(18)30052-3. doi: 10.1016/j.syapm.2018.06.002 epub 8. Juni 2018
Burckhardt I, Horner S, Burckhardt F, Zimmermann S. 2018.
Detection of MRSA in nasal swabs-marked reduction of time to report for negative reports by substituting classical manual workflow with total lab automation.
Eur J Clin Microbiol Infect Dis. 2018 Jun 25. doi: 10.1007/s10096-018-3308-5. [Epub ahead of print]
Chakraborty S, Kloos B, Roetz N, Schmidt S, Eigenbrod T, Kamitani S, Kubatzky KF. 2018.
Influence of Pasteurella multocida Toxin on the differentiation of dendritic cells into osteoclasts
Immunobiology. 223(2018) 142-150. doi: 10.1016/j.imbio.2017.09.001
Domhan C, Uhl P, Meinhardt A, Zimmermann S, Kleist C, Lindner T, Leotta K, Mier W, Wink M. 2018.
A novel tool against multiresistant bacterial pathogens - lipopeptide modification of the natural antimicrobial peptide ranalexin for enhanced antimicrobial activity and improved pharmacokinetics.
Int J Antimicrob Agents. 2018 Apr 9. pii: S0924-8579(18)30101-8. doi: S0924-8579(18)30101-8.
Domhan C, Wink M, Zimmermann, S. 2018.
Dangerously resistant [Gefährlich resistent]
DAZ Vol. 158 (22): 32-39.
Domhan C, Wink M, Zimmermann, S. 2018.
Overcome antimicrobial resistance [Resistenzen überwinden]
DAZ Vol. 158 (22): 40-43.
Grünvogel O, Colasanti O, Lee JY, Klöss V, Belouzard S, Reustle A, Esser-Nobis K, Hesebeck-Brinckmann J, Mutz P, Hoffmann K, Mehrabi A, Koschny R, Vondran FWR, Gotthardt D, Schnitzler P, Neumann-Haefelin C, Thimme R, Binder M, Bartenschlager R, Dubuisson J, Dalpke AH, Lohmann V. 2018
Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll Like Receptor 3 in Hepatocytes.
Gastroenterologydoi: 10.1053/j.gastro.2018.03.020. [Epub ahead of print] IF 18,392
Héry-Arnaud G, Boutin S, Cuthbertson L, Elborn SJ, Tunney MM. 2018
The lung and gut microbiome: what has to be taken into consideration for cystic fibrosis?
Journal of Cystic Fibrosis Article in press. doi: 10.1016/j.jcf.2018.11.003
Hildebrand D, Eberle ME, Wölfle SM, Egler F, Sahin D, Sähr A, Bode K, Heeg K. 2018.
Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells
Front. Immunol. 9:1224. doi: 10.3389/fimmu.2018.01224
Hildebrand D, Uhle F, Sahin D, Krauser U, Weigand MA, Heeg K. 2018.
The Interplay of Notch Signaling and STAT3 in TLR-Activated Human Primary Monocytes.
Front. Cell. Infect. Microbiol. 8:241. doi: 10.3389/fcimb.2018.00241
Jakobs M, Klein S, Eigenbrod T, Unterberg AW, Sakowitz OW. 2018.
The SiLuDrain Trial: a prospective randomized controlled trial comparing standard versus silver-impregnated lumbar drains.
J Neurosurg. 2018 Jun 15:1-8 doi: 10.3171/2018.1.JNS181522 [Epub ahead of print]
Keller P, Freund I, Marchand V, Bec G, Huan R, Motorin Y, Eigenbrod T, Dalpke A, Heim M. 2018.
Double methylation of tRNA-U54 to 2'-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7
Nucleic Acids Res, 2018 Aug 8. doi: 10.1093/nar/gky644
Klein S, Klotz M, Eigenbrod T. 2018.
First isolation of Mycoplasma canis from human tissue samples following a dog bite.
New Microbes and New Infections 2018. 25:14-15 doi: 10.1016/j.nmni.2018.05.003.
Klein S, Nurjadi D, Horner S, Heeg K, Zimmermann S, Burckhardt I. 2018
Significant increase in cultivation of Gardnerella vaginalis, Alloscardovia omnicolens, Actinotignum schaalii, and Actinomyces spp. in urine samples with total laboratory automation.
Eur J Clin Microbiol Infect Dis. 2018 Apr 13. doi: 10.1007/s10096-018-3250-6
Kubatzky KF, Uhle F, Eigenbrod T. 2018.
From macrophage to osteoclast – How metabolism determines function and activity
Cytokine (2018). doi: 10.1016/j.cyto.2018.06.013
Nurjadi D, Heeg K, Weber ANR, Zanger P. 2018.
Toll-like receptor 9 (TLR-9) promotor polymorphisms and gene expression are associated with persistent Staphylococcus aureus nasal carriage
Clin Microbiol Infect. 2018. doi: 10.1016/j.cmi.2018.02.014
Nurjadi D, Boutin S, Dalpke A, Heeg K, Zanger P. 2018.
Draft Genome Sequence of Staphylococcus aureus Strain HD1410, Isolated from a Persistent Nasal Carrier
Genome Announc. 10;6(19). pii: e00411-18. doi: 10.1128/genomeA.00411-18.
Richter DC, Heininger A, Brenner T, Hochreiter M, Bernhard M, Briegel J, Dubler S, Grabein B, Hecker A, Kruger WA, Mayer K, Pletz MW, Storzinger D, Pinder N, Hoppe-Tichy T, Weiterer S, Zimmermann S, Brinkmann A, Weigand MA, Lichtenstern C. 2018
Bacterial sepsis : Diagnostics and calculated antibiotic therapy.
Anaesthesist. 2018 Jan 30. doi: 10.1007/s00101-017-0396-z [Epub ahead of print]
Rollenske T, Szijarto V, Lukasiewicz J, Guachalla LM, Stojkovic K, Hartl K, Stulik L, Kocher S, Lasitschka F, Al-Saeedi M, Schröder-Braunstein J, von Frankenberg M, Gaebelein G, Hoffmann P, Klein S, Heeg K, Nagy E, Nagy G, Wardemann H. 2017.
Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen.
Nature Immunology 2018. doi: 10.1038/s41590-018-0106-2
Schirmer B, Giehl K, Kubatzky KF. 2018
Report of the Signal Transduction Society Meeting 2017-Metabolism in Health and Disease.
Int J Mol Sci. 2018 Feb 12;19(2). pii: E549. doi: 10.3390/ijms19020549.
Strebovsky J, Zimmer J and Dalpke AH. 2018
SOCS
Encyclopedia of Signaling Molecules. Choi, Sangdun (Ed.), Springer, New York, 2nd Edition, 5061-5068 (2018), ISBN 978-3-319-67198-7, ISBN 978-3-319-67199-4 (eBook), doi: 10.1007/978-3-319-67199-4
Publikationen 2017
Boutin S, Dalpke A. 2017
Acquisition and adaptation of the airway microbiota in the early life of cystic fibrosis patients
Molecular and Cellular Pediatrics (2017) 4:1. DOI 10.1186/s40348-016-0067-1
Boutin S, Depner M, Stahl M, Graeber SY, Dittrich SA, Legatzki A, von Mutius E, Mall M, Dalpke AH. 2017
Comparison of Oropharyngeal Microbiota from Children with Asthma and Cystic Fibrosis.
Mediat Inflamm. 2017;2017:5047403. doi: 10.1155/2017/5047403. Epub 2017 Dec 27.
Boutin S, Graeber SY, Stahl M, Dittrich SA, Mall MA, Dalpke AH.2017
Chronic but not intermittent infection with Pseudomonas aeruginosa is associated with global changes of the lung microbiome in cystic fibrosis.
Eur Respir J 50 (4): 1701086. doi: 10.1183/13993003.01086-2017 in press.
Boutin S, Hagenfeld D, Zimmermann H, El Sayed N, Höpker T, Greiser HK, Becher H, Kim TS, Dalpke AH. 2017
Clustering of subgingival microbiota reveals microbial disease ecotypes associated with clinical stages of periodontitis in a cross-sectional study.
Front Microbiol. 8:340. doi: 10.3389/fmicb.2017.00340
Braun MS, Wang E, Zimmermann S, Boutin S, Wink M. 2017
Kocuria uropygioeca sp. nov. and Kocuria uropygialis sp. nov., isolated from the preen glands of Great Spotted Woodpeckers (Dendrocopos major).
Syst Appl Microbiol. 2017 Nov 15. pii: S0723-2020(17)30136-4. doi: 10.1016/j.syapm.2017.09.005. [Epub ahead of print]
Burckhardt I, Panitz J, Burckhardt F, Zimmermann S. 2017
Identification of Streptococcus pneumoniae: Development of a Standardized Protocol for Optochin Susceptibility Testing Using Total Lab Automation
BioMed Research International; Volume 2017 (2017), Article ID 4174168, 7 pages. doi: 10.1155/2017/4174168
Chakraborty S, Kloos B, Harre U, Schett G, Kubatzky KF. 2017
Pasteurella multocida Toxin Triggers RANKL-Independent osteoclastogenesis
Front. Immunol. doi: 10.3389/fimmu.2017.00185
Chakraborty S, Kloos B, Roetz N, Schmidt S, Eigenbrod T, Kamitani S, Kubatzky KF. 2017
Influence of Pasteurella multocida Toxin on the differentiation of dendritic cells into osteoclasts.
Immunobiology. 2018 Jan;223(1):142-150. doi: 10.1016/j.imbio.2017.09.001. Epub 2017 Sep 12.
Decker SO, Sigl A, Grumaz C, Stevens P, Vainshtein Y, Zimmermann S, Weigand MA, Hofer S, Sohn K, Brenner T. 2018
Immune-Response Patterns and Next Generation Sequencing Diagnostics for the Detection of Mycoses in Patients with Septic Shock—Results of a Combined Clinical and Experimental Investigation
Int. J. Mol. Sci. 2017, 18, 1796. doi: 10.3390/ijms18081796.
Giesbrecht K, Eberle ME, Wölfle SJ, Sahin D, Sähr A, Oberhardt V, Menne Z, Bode KA, Heeg K, Hildebrand D. 2017
IL-1β As Mediator of Resolution That Reprograms Human Peripheral Monocytes toward a Suppressive Phenotype.
Front Immunol. Aug 3;8:899. doi: 10.3389/fimmu.2017.00899. eCollection 2017.Front Immunol.
Günther F, Blessing B, Tacconelli E, Mutters NT. 2017
MRSA decolonization failure-are biofilms the missing link?
Antimicrob Resist Infect Control. 2017 Mar 28; 6:32. doi: 10.1186/s13756-017-0192-1
Hagenfeld D, Mutters NT, Harks I, Koch R, Kim TS, Prehm P. 2017
Hyaluronan-mediated mononuclear leukocyte binding to gingival fibroblasts.
Clin Oral Investig. 2017 Aug 12. doi: 10.1007/s00784-017-2188-x.
Hellmuth I, Freund I, Schlöder J, Seidu-Larry S, Thüring K, Slama K, Langhanki J, Kaloyanova S, Eigenbrod T, Krumb M, Röhm S, Peneva K, Opatz T, Jonuleit H, Dalpke AH, Helm M. 2017
Bioconjugation of small molecules to RNA impedes its recognition by Toll-like receptor 7 (TLR7).
Front. Immunol. 8:312. doi: 10.3389/fimmu.2017.00312
Ibert, F., Eckstein, M., Günther, F., Mutters, N.T.
The relationship between subjective perception and the psychological effects of patients in spatial Isolation. 2017
GMS Hyg Infect Control. 2017;12:Doc11
Kamradt T, Klein S, Zimmermann S, Schröder-Braunstein J, Fürstenberg CH, Hensel C, Weidner N, Hug A. 2017
Bacterial Load of Conditioned Pressure Ulcers is not a Predictor for Early Flap Failure in Spinal Cord Injury.
Spinal Cord advance online publication. January 10, 2017; doi:10.1038/sc.2016.186 (epub January 10, 2017)
Kaiser S J, Mutters N T, Blessing B, Günther F. 2017.
Natural isothiocyanates express antimicrobial activity against developing and mature biofilms of Pseudomonas aeruginosa.
Fitoterapia. 2017 Apr 5; doi: 10.1016/j.fitote.2017.04.006
Klöss V, Grünvogel O, Wabnitz G, Eigenbrod T, Ehrhardt S, Lasitschka F, Lohmann V and Dalpke AH. 2017
Interaction and Mutual Activation of Different Innate Immune Cells Is Necessary to Kill and Clear Hepatitis C Virus-Infected Cells.
Front. Immunol. 8:1238 doi: 10.3389/fimmu.2017.01238
Kuon RJ, Togawa R, Vomstein K, Weber M, Goeggl T, Strowitzki T, Markert UR, Zimmermann S, Daniel V, Dalpke AH, Toth B. 2017
Higher prevalence of colonization with Gardnerella vaginalis and gram-negative anaerobes in patients with recurrent miscarriage and elevated peripheral natural killer cells.
J Reprod Immunol. 120:15-19. doi: 10.1016/j.jri.2017.03.001.
Marchand V, Pichot F, Thüring K, Ayadi L, Freund I, Dalpke A, Helm M, Motorin Y. 2017
Next-Generation Sequencing-Based RiboMethSeq Protocol for Analysis of tRNA 2'-O-Methylation.
Biomolecules. 2017 Feb 9;7(1). pii: E13. doi: 10.3390/biom7010013.
Mijosek T, Jelic M, Mijosek V, Maguire I. 2017
Molecular and morphometric characterisation of the invasive signalcrayfish populations in Croatia
Limnologica 63 (2017) 107–118. doi: 10.1016/j.limno.2017.02.003
Mracsko E, Stegemann-Koniszewski S, Na SY, Dalpke A, Bruder D, Lasitschka F, Veltkamp R. 2017
A Mouse Model of Post-Stroke Pneumonia Induced by Intra-Tracheal Inoculation with Streptococcus pneumoniae.
Cerebrovasc Dis. 2017 Jan 4;43(3-4):99-109. doi: 10.1159/000452136.
Mutters NT, De Angelis G, Restuccia G, Di Muzio F, Schouten J, Hulscher M, Antonelli M, Tacconelli E. 2017
Use of evidence-based recommendations in an antibiotic care bundle for the intensive care unit.
Int J Antimicrob Agents. 2017 Jul 10. doi: 10.1016/j.ijantimicag.2017.06.020
Mutters NT, Friedrich AW. 2017
Infectiepreventieopleiding: metacompetentie en Europese competentie.
Ned Tijdschr Med Microbiol 2017;25:nr3
Mutters NT, Heeg K, Späth I, Henny N, Günther F. 2017
Improvement of infection control management by routine molecular evaluation of pathogen clusters.
Diagn Microbiol Infect Dis. 2017 Jan 25 doi: 10.1016/j.diagmicrobio.2017.01.013
Mutters NT, Malek V, Agnandji ST, Günther F, Tacconelli E. 2017
Evaluation of the scientific impact of the Ebola epidemic: a systematic review.
Clin Microbiol Infect. 2017 Sep 4.
Ng Kuet Leong N, Brombacher F, Dalpke AH and Weitnauer M. 2017
Crosstalk between glucocorticoids and IL-4 modulates Ym1 expression in alternatively activated myeloid cells.
Immunobiology, in press doi: 10.1016/j.imbio.2017.02.003
Nurjadi D, Heeg K, Zanger P. 2017.
A Trial of Antibiotics for Smaller Skin Abscesses.
N Engl J Med. 28;377(26):e36. doi: 10.1056/NEJMc1711124.
Nurjadi D, Klein S, Zimmermann S, Heeg K, Zanger P. 2017
Transmission of ST8-USA300 Latin American Variant Methicillin-Resistant Staphylococcus aureus on a Neonatal Intensive Care Unit: Recurrent Skin and Soft- Tissue Infections as a Marker for Epidemic Community-Associated-MRSA Colonization.
Infect Control Hosp Epidemiol. 2017 May 18:1-3. doi: 10.1017/ice.2017.88. [Epub ahead of print]
Pulcini C, Tebano G, Mutters NT, Tacconelli E, Cambau E, Kahlmeter G, Jarlier V; EUCIC-ESGAP-EUCAST Selective Reporting Working Group.2017
Selective reporting of antibiotic susceptibility test results in European countries: an ESCMID cross-sectional Survey.
Int J Antimicrob Agents. 2017
Richter DC, Heininger A, Brenner T, Hochreiter M, Bernhard M, Briegel J, Dubler S, Grabein B, Hecker A, Krüger WA, Mayer K, Pletz MW, Störzinger D, Pinder N, Hoppe-Tichy T, Weiterer S, Zimmermann S, Brinkmann A, Weigand MA, Lichtenstern C. 2017
Bacterial sepsis : Diagnostics and calculated antibiotic therapy.
Anaesthesist. 2017 Oct;66(10):737-761. doi: 10.1007/s00101-017-0363-8.
Schmitt FCF, Freund I, Weigand MA; Helm M, Dalpke AH, Eigenbrod E. 2017
Identification of an optimized 2′-O-methylated trinucleotide RNA motif inhibiting Toll-like receptors 7 and 8
RNA.23(9):1344-1355. doi:10.1261/rna.061952.117
Tschudin-Sutter S, Lucet JC, Mutters NT, Tacconelli E, Zahar JR, Harbarth S. 2017
Contact precautions for preventing nosocomial transmission of ESBL-producing Escherichia coli - a point/counterpoint review.
Clin Infect Dis. 2017 Apr 3. doi: 10.1093/cid/cix258.
Zimmermann S, Burckhardt I. 2017
Development and Application of MALDI-TOF for Detection of Resistance Mechanisms
Eds. Shah H, Ghabria S.
MALDI-TOF and TANDEM MS for Clinical Microbiology, John Wiley & Sons Ltd., 2017, 1st Edition.
Publikationen 2016
Braun MS, Zimmermann S, Danner M, Rashid H, Wink M. 2016
Corynebacterium uropygiale sp. nov., isolated from the preen gland of Turkeys (Meleagris gallopavo).
Syst Appl Microbiol http://dx.doi.org/10.1016/syapm.2015.12.001
Bender JK, Fleige C, Klare I, Fiedler S, Mischnik A, Mutters NT, Dingle KE, Werner G. 2016
Detection of a cfr(B) Variant in German Enterococcus faecium Clinical Isolates and the Impact on Linezolid Resistance in Enterococcus spp.
PLoS One November 28, 2016
Borde JP, Sitaru G, Kopp WH, Ruhparwar A, Ehlermann P, Lasitschka L, Dalpke A, Heininger A. 2016
Heart transplantation as salvage therapy for progressive prosthetic valve endocarditis due to methicillin-resistant Staphylococcus epidermidis (MRSE).
Journal of Cardiothoracic Surgery (2016) 11:100; doi: 10.1186/s13019-016-0505-0
Burckhardt I, Panitz J, van der Linden M, Zimmermann S. 2016
Streptococcus pneumoniae as an agent of urinary tract infections – a laboratory experience from 2010 to 2014 and further characterization of strains
Diagn Microbil Infect Dis; 86(2016)97-101. doi: 10.1016/j.diagmicrobio.2016.06.009
Dalpke A, Hofko M, Zimmermann S. 2016
Development of a real-time PCR protocol requiring minimal handling for detection of
vancomycin-resistant enterococci (VRE) with the fully automated BD MAX System
J. Clin. Microbiol.; doi: 10.1128/JCM.00768-16
Dalpke A, Zimmermann S, Schnitzler P. 2016
Underdiagnosing of Mycoplasma pneumoniae infections as revealed by use of a respiratory multiplex PCR panel.
Diagn Micr Infec Dis; doi: 10.1016/j.diagmicrobio.2016.06.013 [in press]
http://audioslides.elsevier.com//ViewerLarge.aspx?source=1&doi=10.1016/j.diagmicrobio.2016.06.013
Dubler S, Zimmermann S, Fischer M, Schnitzler P, Bruckner T, Weigand MA, Frank U, Hofer S, Heininger A. 2016
Bacterial and viral contamination of breathing circuits after extended use – an aspect of patient safety?
Acta Anaesthesiologica Scandinavica; http://www.ncbi.nlm.nih.gov/pubmed/27470996
Günther F, Merle U, Frank U, Gaida MM, Mutters NT. 2016
Pseudobacteremia outbreak of biofilmforming Achromobacter xylosoxidans – environmental Transmission
BMC Infectious Diseases (2016) 16:584; doi: 10.1186/s12879-016-1909-0
Günther F, Rudolph K, Frank U, Mutters NT. 2016
Improvement of Hand Hygiene Quality andCompliance Using Bioburden Measurementand Online Feedback in Germany
Infect Control Hosp Epidemiol 2016;1–4
Günther F, Scherrer M, Kaiser SJ, DeRosa A, Mutters NT. 2016
Comparative testing of disinfectant efficacy on planktonic bacteria and bacterial biofilms using a new assay based upon kinetic analysis of metabolic activity.
J Appl Microbiol. 2016 Nov 21. doi: 10.1111/jam.13358. [Epub ahead of print]PMID: 27868317 [PubMed - as supplied by publisher]
Hildebrand D, Kubatzky KF. 2016
Phospho-Flow Analysis of Primary Mouse Cells After HDAC Inhibitor Treatment.
Methods Mol Biol. 2017;1510:233-243.
Kaase M, Schimanski S, Schiller R, Beyreiß B, Thürmer A, Steinmann J, Kempf VA, Hess C, Sobottka I, Fenner I, Ziesing S, Burckhardt B, von Müller L, Hamprecht A, Tammer I, Wantia N, Becker K, Holzmann T, Furitsch M, Volmer G, Gatermann SG. 2016
Multicentre investigation of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in German hospitals.
Int J Med Microbiol.; doi: 10.1016/j.ijmm.2016.05.009 [in press]
Kaiser SJ, Mutters NT, Backhaus J, Frank U, Günther F. 2016
Sterility testing of injectable products: evaluation of the growth based BacT/ALERT® 3D™ Dual T culture system.
PDA J Pharm Sci Technol; June 20, 2016; doi:10.5731/pdajpst.2016.006460
Kaiser SJ, Mutters NT, DeRosa A, Ewers C, Frank U, Günther F. 2016
Determinants for persistence of Pseudomonas aeruginosa in hospitals: interplay between resistance, virulence and biofilm formation
Eur J Clin Microbiol Infect Dis; doi: 10.1007/s10096-016-2792-8
Klein S, Nurjadi D, Eigenbrod T, Bode KA. 2016
Evaluation of antibiotic resistance to orally administrable antibiotics in staphylococcal bone and joint infections in one of the largest university hospitals in Germany: is there a role for fusidic acid?
Int J Antimicrob Agents http://dx.doi.org/10.1016/ijantimicag.2015.12.002
Mijošek V, Lasitschka F, Warth A, Zabeck H, Dalpke AH, Weitnauer M. 2016
Endoplasmic Reticulum Stress Is a Danger Signal Promoting Innate Inflammatory Responses in Bronchial Epithelial Cells.
J Innate Immun. 2016;8(5):464-78. doi: 10.1159/000447668.
Mutters NT, Bieber CP, Hauck C, Reiner G, Malek V, Frank U. 2016
Comparison of livestock-associated and health care–associated MRSA—genes, virulence, and resistance
Diagnostic Microbiology and Infectious Disease; xxx (2016) xxx–xxx [in press]
Mutters NT, Guenther F, Frank U, Mischnik A.2016
Costs and possible benefits of a two-tier infection control management strategy consisting of
active screening for multidrug-resistant organisms and tailored control measures.
Journal of Hospital Infection; xxx (2016) 1-6; http://dx.doi.org/10.1016/j.jhin.2016.02.013
Mutters R, Mutters NT.
Hygiene and infection control measures in intensive care units.
Med Klin Intensivmed Notfmed; 2016 May 4.
Noack K, Mahendrarajah N, Hennig D, Schmidt L, Grebien F, Hildebrand D, Christmann M, Kaina B, Sellmer A, Mahboobi S, Kubatzky K, Heinzel T, Krämer OH. 2016
Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells.
Arch Toxicol.2016 Nov 2. [Epub ahead of print]
Nurjadi D, Kain M, Marcinek P, Gaile M, Heeg K, Zanger P. 2016
Ratio of T-Helper Type 1 (Th1) to Th17 Cytokines in Whole Blood Is Associated With Human β-Defensin 3 Expression in Skin and Persistent Staphylococcus aureus Nasal Carriage
J INFECT DIS. 2016;214:1744–51 DOI: 10.1093/infdis/jiw440
Rappold LC, Vogelgsang L, Klein S, Bode K, Enk AH, Haenssle HA.
Primary cutaneous diphtheria: management, diagnostic workup, and treatment as exemplified by a rare case report.
J Dtsch Dermatol Ges. 2016 Jul;14(7):734-6.
Sastalla I, Monack DM, Kubatzky KF. 2017
Editorial: Bacterial Exotoxins: How Bacteria Fight the Immune System.
Front Immunol. 2016 Aug 2;7:300. doi: 10.3389/fimmu.2016.00300. No abstract available.
Tacconelli E, Cataldo MA, Paul M, Leibovici L, Kluytmans J, Schröder W, Foschi F, De Angelis G,
De Waure C, Cadeddu C, Mutters NT, Gastmeier P, Cookson B. 2016
STROBE-AMS: recommendations to optimise reporting of epidemiological studies on antimicrobial resistance and informing improvement in antimicrobial stewardship.
BMJ Open; 6:e010134.doi:10.1136/bmjopen-2015-010134
Tacconelli E, Müller NF, Lemmen S, Mutters NT, Hagel S, Meyer E. 2016
Infektionsrisiko bei aseptischen operativen Eingriffen.
Dtsch Arztebl Int 2016; 113: 271–278.doi: 10.3238/arztebl.2016.0271
Weitnauer M, Mijosek V, Dalpke AH. 2016
Control of local immunity by airway epithelial cells.
Mucosal Immunol. 2016 Mar; 9(2):287-98. doi: 10.1038/mi.2015.126. Epub 2015 Dec 2. Review
Zimmer J, Weitnauer M, Boutin S, Küblbeck G, Thiele S, Walker P, Lasitschka F, Lunding L, Orinska Z, Vock C, Arnold B, Wegmann M, Dalpke A. 2016
Nuclear localization of suppressor of cytokine signaling-1 regulates local immunity in the lung fronstiers in Immunology http://dx.doi.org/10.3389/fimmu.2016.00514
Publikationen 2015
Al-Ani, I., S. Zimmermann, J. Reichling, M. Wink. 2015
Pharmacological synergism o bee venom and melittin with antibiotics and plant secondary metabolites against multi-drug resistant microbial pathogens.
Phymed 22: 245-255
Boutin, S., S.Y. Graeber, M. Weitnauer, J. Panitz, M.Stahl, D. Clausnitzer, L. Kaderali, G. Einarsson, M.M. Tunney, J.S. Elborn, M.A. Mall, A.H. Dalpke. 2015
Comparison of microbiomes from different niches of upper and lower airways in children and adolescents with cystic fibrosis.
PLOS One 10(1): e0116029; doi: 10.1371/journal.pone.0116029
Brooke, R.J., N.T. Mutters, O. Péter, M.E.E. Kretzschmar. 2015
Exposure to low doses of Coxiella burnetii caused high illness attack rates: Insights from combining human challenge and outbreak data.
Epidemics http://dx.doi.org/10.1016/j.epidem.2015.12.004
Dalpke, A.H., M. Hofko, F. Hamilton, L. Mackenzie, S. Zimmermann, K. Templeton. 2015
Evaluation of the BD MAXTM StaphSR assay for rapid identification of Staphylococcus aureus and methicillin-resistant S. aureus in positive blood culture broths.
J Clin Microbiol doi:10.1128/JCM.01922-15
Dapunt, U., O. Spranger, S. Gantz, I. Burckhardt, S. Zimmermann, G. Schmidmaier, A. Moghaddam. 2015
Are atrophic long-bone nonunions associated with low-grade infections?
Therapeutics and Clinical Risk Management 11: 1843-1852
Eigenbrod, T., A.H. Dalpke. 2015
Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses.
J immunol doi:10.4049/jimmunol.1500530
Eigenbrod, T., P. Keller, S. Kaiser, K. Rimbach, A.H. Dalpke, M. Helm. 2015
Recognition of Specified RNA Modifications by the Innate Immune System.
Methods Enzymol 560: 73-89
Eigenbrod, T., K. Pelka, E. Latz, B. Kreikemeyer, A.H. Dalpke. 2015
TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
J immunol doi:10.4049/jimmunol.1403173
F. Günther, S.J. Kaiser, T. Fries, U. Frank, N.T. Mutters. 2015
Susceptibility of multidrug resistant clinical pathogens to a chlorhexidine formulation
J PREV MED HYG 2015; 56:E1-E4
Gielen, V., A. Sykes, J. Zhu, B. Chan, J. Macintyre, N. Regamey, E. Kieninger, A. Gupta, A. Shoemark, C. Bossley, J. Davies, S. Saglani, P. Walker, S.E. Nicholson, A.H. Dalpke, Q.M. Kon, A. Bush, S.L. Johnston, M.R. Edwards. 2015
Increased nuclear SOCS1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate inerferons.
J Allergy Clin Immunol pii: S0091-6749(14)03667-7; doi: 10.1016/j.jaci.2014.11.039. [Epub ahead of print]
Dagmar Hildebrand, Klaus Heeg, Katharina F. Kubatzky. 2015
Pasteurella multocida Toxin manipulaties T Cell Differentiation
Frontiers in Micorbiology doi:10.3389/fmicb.2015.01273
Klare, I., C. Fleige, U. Geringer, A. Thürmer, J. Bender, N.T. Mutters, A. Mischnik, G. Werner. 2015
Increased frequency of linezolid resistance among clinical Enterococcus faecium isolates from German hospital patients.
J Glob Antimicrob Resist
Bianca Kloos, Sushmita Chakraborty, Sonja G. Lindner, Katrin Noack, Ulrike Harre, Georg Schett, Oliver H. Krämer, Katharina F. Kubatzky. 2015
Pasteurella multocida toxin- induced osteoclastogenesis requires mTOR activation
Cell Communication and Signaling DOI:10.1186/s12964-015-0117-7
Lichtenstern, C., C. Herold, M. Mieth, T. Brenner, S. Decker, C.J. Busch, S. Hofer, S. Zimmermann, M.A. Weigand, M. Bernhard. 2015
Relevance of Candida and other mycoses for morbidity and mortality in severe sepsis and septic shock due to peritonitis.
Mycosis doi:10.1111/myc.12331
Liesz, A., A. Dalpke, E. Mracsko, D.J. Antoine, S. Roth, W. Zhou, H. Yang, S.Y. Na, M. Akhisaroglu, T. Fleming, T. Eigenbrod, P.P. Nawroth, K.J. Tracey, R. Veltkamp. 2015
DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury.
J Neurosci 35(2): 583-598
Mischnik,A., E. Tacconelli, N.T. Mutters. 2015
Fidaxomicin: Ein neues makrozyklisches Antibiotikum halbiert die Rückfallquote bei Darminfektionen durch Clostridium difficile. Expertenkommentar.
J Med Drug Rev 5: 49-59
Mischnik, A., M. Trampe, S. Zimmermann. 2015
Evaluation of the Impact of Automated Specimen Inoculation, Using Previ Isola, on the Quality of and Technical Time for Stool Cultures.
Ann Lab Med http://dx.doi.org/10.3343/alm.2015.35.1
Mutters, N.T., I. Burckhardt, K. Heeg. 2015
MALDI-TOF Mass Spectrometry as a Tool for Epidemiological Outbreak Analysis - Can it Work?
J Med Diagn Meth 4 (4), 184
Mutters, N.T., U. Frank. 2015
Prävention nosokomialer Infektionen in Risikobereichen.
J Env and Occu Health Sciences 20(2): 89-95
Mutters, N.T., U. Frank. 2015
Prävention nosokomialer Infektionen.
In: Handbuch der Intensivpflege, 42. Ausgabe
Mutters, N.T., F. Günther, S. Kaiser, T. Fries, U. Frank. 2015
Czy wasz Antyseptyk jest skuteczny przeciwko klinicznym scczepom wielolekoopornych drobnoustrojow? Preparat diglukonianu chlorheksydyny wykazuje skutecznosc nawet w nizszych stezeniach.
Zakazenia 15(6): 50-52
Mutters, N.T., F. Günther, A. Sander, A. Mischnik, U. Frank. 2015
Influx of multidrug-resistant organisms by country-to-country transfer of patients.
BMC Infect Dis 15(1): 466 doi:10.1186/s12879-015-1173-8
Mutters, N.T., A. Mischnik. 2015
Vancomycin-resistant enterococci: increased mortality with tigecycline?
Dtsch Med Wochenschr 140(11): 784
Mutters, N.T., T.R. Neubert, R. Nieth, R. Mutters. 2015
The role of Octenidol®, Glandomed® and chlorhexidine mouthwash in the prevention of mucositis and in the reduction of the oropharyngeal flora: a double-blind-randomized controlled trial.
GMS Hyg Infect Control 2015 Feb 13;10:Doc05. doi: 10.3205/dgkh000248. PMID: 25699228
Mutters, N.T., E. Tacconelli. 2015
Infection Prevention and Control in Europe - the picture in the Mosaic.
Clin Microbiol Infect 2015 Jun 19
Mutters, N.T., G. Werner, E. Tacconelli, A. Mischnik. 2015
Vancomycin-resistente Enterokokken: Welche Therapieoptionen gibt es?
Dtsch Med Wochenschr 140: 42-45
Mutters, N.T., S. Zimmermann, M. Kaase, A. Mischnik. 2015
Activity of temocillin, mecillinam, ceftazidime, and ceftazidime/avibactam against carbapenem-non-susceptible Enterobacteriaceae without carbapenemase production.
Eur J clin Microbiol Infect Dis doi:10.1007/s10096-015-2498-3
Nurjadi, D., B. Friedrich-Jänicke, J. Schäfer, P.J.J. Van Genderen, A. Goorhuis, A. Perignon, A. Neumayr, A. Mueller, A. Kantele, M. Schunk, J. Gascon, A. Stich, C. Hatz, E. Caumes, M.P. Grobusch, R. Fleck, F.P. Mockenhaupt, P. Zanger. 2015
Skin and soft tissue infections in intercontinental travellers and the import of multi-resistant Staphylococcus aureus to Europe.
Clin Microbial Infect 21: 567.e1-567.e10
Nurjadi, D., J. Schäfer, B. Friedrich-Jänicke, A. Mueller, A. Neumayr, A. Calvo-Cano, A. Goorhuis, N. Molhoek, H. Lagler, A. Kantele, P.J.J. Van Genderen, J. Gascon, M.P. Grobusch, E. Caumes, C. Hatz, R. Fleck, F.P. Mockenhaupt, P. Zanger. 2015 Predominance of dfrG as determinant of trimethoprim resistance in imported Staphylococcus aureus Clin Microbial Infect 21: 1095.e5-1095.e9
Otter, J.A., N.T. Mutters, E. Tacconelli, A. Gikas, A.H. Holmes. 2015
Controversies in guidelines for the control of multidrug-resistant Gram-negative bacteria in EU countries.
Clin Microbiol Infect 2015 Jun 19
Oumouna, M., M. Weitnauer, V. Mijosek, L.M. Schmidt, T. Eigenbrod, A.H. Dalpke. 2015
Cell-contact dependent inhibition of monocytes by airway epithelial cells and reversion by infection with Respiratory Syncytial Virus.
Immunobiology 220: 1240-1245
Rimbach, K., S. Kaiser, M. Helm, A.H. Dalpke, T. Eigenbrod. 2015
2'-O-Methylation within Bacterial RNA Acts as Suppressor of TLR7/TLR8 Activation in Human Innate Immune Cells.
J Innate Immunity 7(5): 482-493
Rodriguez-Bano, J., M.D. Toro, J. Lopez-Delgado, N.T. Mutters, A. Pascual. 2015
Minimum requirements in infection control.
Clin Microbiol Infect 2015 Jun 19
Aline Sähr, Sandra Förmer, Dagmar Hildebrand, Klaus Heeg. 2015
T-cell activation or tolerization: the Yin and Yang of bacterial superantigens
Frontiers in Micorbiology doi:10.3389/fmicb.2015.01153
Senft, J.D., B. Carstensen, A. Mischnik, R. Warschkow, B.P Müller-Stich, G.R. Linke. 2015
Endolumenal colon occlusion reduces peritoneal contamination during a transrectal NOTES procedure: a controlled porcine survival study.
Surg Endosc DOI 10.1007/s00464-015-4582-2
Stammler, D., T. Eigenbrod, S. Menz, J.S. Frick, M.J. Sweet, M.R. Shakespear, J. Jantsch, I. Siegert, S. Wölfle, J.D. Langer, I. Oehme, L. Schaefer, A. Fischer, J. Knievel, K. Heeg, A.H. Dalpke, K.A. Bode. 2015 Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1ß via a Caspase-1-Independent Mechanism. J immunol doi:10.4049/jimmunol.1501195
Tanja Wiedenmann, Stefanie Ehrhardt, Daniela Cerny, Dagmar Hildebrand, Sabrina Klein, Klaus Heeg, Katharina F. Kubatzky. 2015
Erythropoietin acts as an anti-inflammatory signal on murine mast cells
Molecular Immunology 65:68-76
Zingg, W., N.T. Mutters, S. Harbarth, A.W. Friedrich. 2015
Education in Infection Control: a need for European certification.
Publikationen 2014
Bösel, J., S. Klein, B. Ellger. 2014
SOP Infektion
Intensivmedizin up2date 10: 278-281
Borg, M.A., M. Hulscher, E.A. Scicluna, J. Richards, J.M. Azanowsky, D. Xuereb, A. Huis, M.L. Moro, H.C. Maltezou, U. Frank. 2014
Prevention of methicillin-resistant Staphylococcus aureus bloodstream infections in European hospitals: moving beyond policies.
J Hosp Infect 87(4): 203-211
Brenner, T., T. Fleming, F. Uhle, S. Silaff, F. Schmitt, E. Salgado, A. Ulrich, S. Zimmermann, T. Bruckner, E. Martin, A. Bierhaus, P.P. Nawroth, M.A. Weigand, S. Hofer. 2014
Methylglyoxal as a new biomarker in patients with septic shock: an observational clinical study.
Crit Care 18(6): 683-693
Bretz, N.P., J. Ridinger, A.-K. Rupp, K. Rimbach, S. Keller, C. Rupp, F. Marmé, L. Umansky, V. Umansky, T. Eigenbrod, M. Sammar, P. Altevogt. 2014
Body fluid exosomes promote secretion of inflammatory cytokines in monocytic cells via TLR signaling.
J Biol Chem 288(51): 36691-36702
Burckhardt, I., J. Roemer, F. Burckhardt, S. Zimmermann. 2014
Serotyping of pneumococci: evaluation of the genetic approach and performance with clinical samples.
Diagn Micr Infec Dis 80(4): 274-277
Dalpke, A.H., M. Hofko, C. Stock, S. Zimmermann. 2014
Evaluation of the BD Max MRSA XT Assay for Use with Different Swab Types.
J Clin Microbiol 52(12): 4343-4346
Dapunt, U., B. Lehner, I. Burckhardt, S. Zimmermann, G.M. Hänsch, V. Ewerbeck. 2014
Evaluation of implant sonication as a diagnostic tool in implant-associated infections.
J Appl Biomater Func 12(3): 135-140
Dapunt, U., A. Mischnik, S. Goeppinger, B. Lehner. 2014
A persistent case of tuberculosis of the pubic symphysis and pubic bone.
BMJ Case Rep doi:10.1136/bcr-2013-203456
Franchi, L., T. Eigenbrod, R. Muñoz-Planillo, U. Ozkurede, Y.-G. Kim, A. Chakrabarti, M. Gale Jr., R.H. Silvermann, M. Colonna, S. Akira, G. Núñez. 2014
Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization an K+ Efflux.
J Immunol 193(8): 4214-4222
Gartiser, S., F. Flach, C. Nickel, M. Stintz, S. Damme, A. Schaeffer, L. Erdinger, T.A.J. Kuhlbusch. 2014
Behavior of nanoscale titanium dioxide in laboratory wastewater treatment plants according to OECD 303 A.
Chemosphere 104: 197-204
Gehrig, S., J. Duer, M. Weitnauer, C.J. Wagner, S.Y. Graeber, J. Schatterny, S. Hirtz, A. Belaaouaj, A.H. Dalpke, C. Schultz, M.A. Mall. 2014
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion and amphysema, but not mucus obstruction, in mice with CF-like lung disease.
AJRCCM 189(9): 1082-1092
Giampaoli, S., N. Garrec, G. Donzé, F. Valeriani, L. Erdinger, V.R. Spica. 2014
Regulations concerning natural swimmingponds in Europe: considerations on public health issues.
J Water hHealth 12: 564-572
Hamoud, R., S. Zimmermann, J. Reichling, M. Wink. 2014
Synergistic interactions in two-drug and three-drug combinations (thymol, EDTA and vancomycin) against multi drug resistant bacteria uncluding E. coli.
Phytomedicine 21: 443-447
Heininger, A., U. Frank, P. Schnitzler. 2014
Maßnahmen zum Schutz vor kontaktübertragenen Virusinfektionen.
Krankenhaushyg.up2date 09(04): 233-253
Hildebrand, D., K.A. Bode, D. Rieß, D. Cerny, A. Waldhuber, F. Römmler, J. Strack, S. Korten, J.H. Orth, T. Miethke, K. Heeg, K.F. Kubatzky. 2014
Granzyme A Produces Bioactive IL-1β through a Nonapoptotic Inflammasome-Independent Pathway.
Cell Rep 9(3): 910-917
Hilmi, D., M. Parcina, D. Stollewerk, J. Ostrop, M. Josten, A. Meilaender, U. Zaehringer, T.A. Wichelhaus, G. Bierbaum, K. Heeg, C. Wolz, I. Bekeredjian-Ding. 2014
Heterogeneity of HOst TLR2 Stimulation by Staphylococcus aureus Isolates.
PLOS one 9(5): e96416
Hofko, M., A. Mischnik, M. Kaase, S. Zimmermann, A.H. Dalpke. 2014
Detection of Carbapenemases by Real-Time PCR and Melt Curve Analysis on the BD MAX System.
J Clin Microbiol 52(5): 1701-1704
Jakob, E., R. Max, S. Zimmermann, A.H. Dalpke, W. Alle, M. Becker, F. Mackensen. 2014
Three Years of Experience with QuantiFERON-TB Gold Testing in Patients with Uveitis.
Ocul Immunol & Inflamm 22(6): 478-484
Kaier K., M.L. Lambert, U.K. Frank, W. Vach, M. Wolkewitz, E. Tacconelli, J. Rello, U. Theuretzbacher, M. Martin. 2014
Impact of availability of guidelines and active surveillance in reducing the incidence of ventilator-associated pneumonia in Europe and worldwide.
BMC Infect Dis 14: 199-207
Kaiser, S., K. Rimbach, T. Eigenbrod, A.H. Dalpke, M. Helm. 2014
A modified dinucleotide motif specifies tRNA recognition by TLR7.
RNA 20: 1351-1355
Krause, L., F. Mackensen, U. Pleyer, C.-D. Quentin, F. Seibel, S. Zimmermann. 2014
Infektiös.
In: Entzündliche Augenerkrankungen, Ed.: U. Pleyer, ISBN: 978-3-642-38419-6, Springer-Verlag Berlin Heidelberg, 287-306
Krueger, W.A., A. Heininger, B. Grabein, K. Unertl, M. Sánchez-García. 2014
Selective Digestive Tract Decontamination and Spread of Colistin Resistance: Antibiotic Prophylaxis Is Not a Substitute for Hygiene.
Antimicrob Agents Ch 58(6): 3574-3575
Mischnik, A., J. Stockklausner, N. Hohneder, H.E. Jensen, S. Zimmermann, D.E. Reuss, V. Rickerts, K. Tintelnot, C. Stockklausner. 2014
First case of disseminated cryptococcosis in a Gorilla gorilla.
Mycoses 57(11): 664-671
Mutters, N.T. 2014
Laboratory Automation in Clinical Microbiology: A Quiet Revolution.
Austin J Infect Dis 1(1): 2
Mutters, N.T., F. Günther, A. Heininger, U. Frank. 2014
Device-related infections in long-term healthcare facilities: the challenge of prevention.
Future Microbiol 9(4): 487-495
Mutters, N.T., U. Hägele, D. Hagenfeld, E. Hellwig, U. Frank. 2014
Compliance with infection control practices in an university hospital dental clinic.
GMS Hyg Infect Control 9(3): Doc18
Mutters, N.T., C.J. Hodiamont, M.D. de Jong, H.P.J. Overmeijer, M. van den Boogaard, C.E. Visser. 2014
Performance of Kiestra Total Laboratory Automation Combined with MS in Clinical Microbiology Practice.
Ann Lab Med 34: 111-117
Mutters, N.T., E. Meyle. 2014
Amoxicillin: Pharmaceutical Properties and Clinical Applications.
In: Amoxicillin - Medical Uses, Mechanism of Action and Potential Adverse Effects, Eds.: W.A. Leary, L.M. Kruse, ISBN: 978-1-62948-489-1, Nova Biomedical, New York, 83-100
Rohde, D., C. Schön, M. Boerries, I. Didrihsone, J. Ritterhoff, K.F. Kubatzky, M. Völkers, N. Herzog, M. Mähler, J.N. Tsoporis, T.C. Parker, B. Linke, E. Giannitsis, E. Gao, K. Peppel, H.A. Katus, P. Most. 2014
S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4.
EMBO Mol Med 6: 778-794
Rupp, C., K.A. Bode, F. Chahoud, A. Wannhoff, K. Friedrich, K.-H. Weiss, P. Sauer, W. Stremmel, D.N. Gotthardt. 2014
Risk factors and outcome in patients with primary sclerosing cholangitis with persistent biliary candidiasis.
BMC Infectious Diseases 14: 562-570
Schneeberg, A., R. Ehricht, P. Slickers, V. Baier, H. Neubauer, S. Zimmermann, D. Rabold, A. Lübke-Becker, C. Seyboldt. 2014
DNA microarray based PCR ribotyping Clostridium difficile.
J Clin Microbiol 53(2): 433-442
Tacconelli, E., M.A. Cataldo, S.J. Dancer, G. De Angelis, M. Falcone, U. Frank, G. Kahlmeter, A. Pan, N. Petrosillo, J. Rodriguez-Bano, N. Singh, M. Venditti, D.S. Yokoe, B. Cookson. 2014
ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gramnegative bacteria in hospitalized patients.
Clin Microbiol Infect Suppl 1: 1-55
Weitnauer, M., L. Schmidt, N.N. Kuet Leong, S. Muenchau, F. Lasitschka, V. Eckstein, S. Hübner, J. Tuckermann, A.H. Dalpke. 2014
Bronchial Epithelial Cells Induce Alternatively Activated Dendritic Cells Dependent on Glucocorticoid Receptor Signaling.
J Immunol 93(3): 1475-1484
Wolkewitz, M., A.G. Barnett, M. Palomar Martinez, U. Frank, M. Schumacher for the IMPLEMENT Study Group. 2014
Interventions to control nosocomial infections: study designs and statistical issues.
J Hosp Infect 86: 77-82
Ziegler, S., K. Gartner, U. Scheuermann, T. Zoeller, J. Hantzschmann, B. Over, S. Foermer, K. Heeg, I. Bekeredjian-DIng. 2014
Ca(2+)-related signaling events influence TLR9-induced IL-10 secretion in human B cells.
Eur J immunol 44: 1285-1298
Publikationen 2013
Astani, A., S. Zimmermann, E. Hassan, J. Reichling, K.H. Sensch, P. Schnitzler. 2013
Antimicrobial activity of propolis extract against multidrug-resistant clinical isolates.
Pharmazie 68: 1-7
Beikert, F.C., Z. Anastasiadou, B. Fritzen, U. Frank, M. Augustin. 2013
Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparataive pilot study.
Dermatology 226(1): 47-51
Brooke, R.J., M.E. Kretzschmar, N.T. Mutters, P.F. Teunis. 2013
Human dose response relation for airborne exposure to Coxiella burnetii.
BMC Infect Dis 13(1): 488
Burckhardt, I. 2013
Intrafamily Transmission of Streptococcus pneumoniae and the Protective Power of Vaccination.
Epidemiol 3(4): 1000138
Conrad, A., D. Biehler, T. Nobis, H. Richter, I. Engels, K.Biehler, U. Frank. 2013
Broad spectrum antibacterial activity of a mixture of isothiocyanates from nasturtium (Tropaeoli majoris herba) and horseradish (Armoraciae rusticanae radix).
Drug Res 63(2): 65-68
Dalpke, A.H., M. Hofko, S. Zimmermann. 2013
Development and Evaluation of a Real-Time PCR Assay for Detection of Pneumocystis jirovecii on the Fully Automated BD MAXTM Platform.
J Clin Microbiol 51(7): 2337-2343
Dalpke, A.H., M. Hofko, M. Zorn, S. Zimmermann. 2013
Evaluation of th Fully automated BD MAX Cdiff and Xpert C. difficile Assays for Direct Detection of Clostridium difficile in Stool Specimens.
J Clin Microbiol 51(6): 1906-1908
Doster, A., S. Ziegler, S. Foermer, R.J. Rieker, K. Heeg, I. Bekeredjian-Ding. 2013
PTO-modified CpG oligodeoxynucleotides mimic autoantigens and reveal a potential role for TLR9 in receptor revision.
Immunology 139(2): 166-178
Eigenbrod, T., K.A. Bode, A.H. Dalpke. 2013
Early Inhibition of IL-1ß Expression by IFN-γ Is Mediated by Impaired Binding of NF-κB to the IL-1ß Promotor but Is Independent of Nitric Oxide.
J Immunol 190: 6533-6541
Eigenbrod, T., A.H. Dalpke. 2013
TLR7 inhibition - A novel strategy for pancreatic cancer treatment?
Jak-Stat 2(1): 1-4
Geis, S.,C. Prifert, B. Weissbrich, N. Lehners, G. Egerer, C. Eisenbach, U. Buchholz, E. Aichinger, P. Dreger, K. Neben, U. Burkhardt, A.D. Ho, H.-G. Kräusslich, K. Heeg, P. Schnitzler. 2013
Molecular Characterizatin of a Respiratory Syncytial Virus Outbreak in a Hematology Unit in Heidelberg, Germany.
J Clin Microbiol 51(1): 155-162
Gotthardt, D.N., K.H. Weiss, C. Rupp, K. Bode, I. Eckerle, G. Rudolph, J. Bergemann, P. Kloeters-Plachky, F. Chahoud, M.W. Büchler, P. Schemmer, W. Stremmel, P. Sauer. 2013
Bacteriobilia and fungibilia are associated with outcome in patients with endoscopic treatment of biliary complications after liver transplantation.
Endoscopy 45:890-896
Gumbinger, C., A. Hug, B. Mürle, B. Berger, M. Zorn, K.P. Becker. S. Zimmermann, A.H. Dalpke, R. Veltkamp. 2013
Early blood-based microbiological testing is ineffective in severe stroke patients.
J Neurol Sci 325(1-2): 46-50
Hilmi, D., M. Parcina, K. Bode,J. Ostrop, S. Schuett, K. Heeg, W. Ziebuhr, O. Sommerburg, I. Bekeredjian-Ding. 2013
Functional variation reflects intra-strain diversity of Staphylococcus aureus small colony variants in the host-pathogen interaction.
Int J Med Microbiol 303: 61-69
Kaier, K., U. Frank. 2013
In search of useful methods for measuring health and economic consequences of antimicrobial resistance.
Clin Infect Dis 57(8): 1220-1222
Koschny, R., T. Junghanss, A. Mischnik, M. Karner, M. Kreuter, W. Roth, W. Stremmel, U. Merle, 2013
Development of Miliary Tuberculosis under Infliximab in a Patient with Spondyloarthritis and Suspected Crohn's Disease.
Z Gastroenterol 51: 1177-1183
Kubatzky, K.F., B. Kloos, D. Hildebrand. 2013
Signaling cascades of Pasteurella multocida toxin in immune evasion.
Toxins 5(9): 1664-1681
Lambert, M.-L., M. Palomar, A. Agodi, M. Hiesmayr, A. Lepape, A. Ingenbleek, E.P. Herrejon, S. Blot, U. Frank. 2013
Prevention of ventilator-associated pneumonia in intensive care units: an international online survey.
Antimicrob Resist Infect Control 2: 9
Lehners, N., P. Schnitzler, S. Geis, J. Puthenparambil, M.A. Benz, B. Alber, T. Luft, P. Dreger, C. Eisenbach, C. Kunz, A. Benner, U. Buchholz, E. Aichinger, U. Frank, K. Heeg, A.D. Ho, G. Egerer. 2013
Risk factors and containment of respiratory syncytial virus outbreak in a hematology and transplant unit.
Bone Marrow Transplant 48(12): 1548-153
Liesz, A., H. Rüger, J. Purrucker, M. Zorn, A. Dalpke, M. Möhlenbruch, S. Englert, P.P. Nawroth, R. Veltkamp. 2013
Stress Mediators and Immune Dysfunction in Patients with Acute Cerebrovascular Diseases.
PLoS One 8(9): e74839
Mischnik, A., S. Klein, K. Tintelnot, S. Zimmermann, V. Rickerts. 2013
Kryptokokkose: Kasuistiken, Epidemiologie und Therapiestrategien.
Dtsch Med Wochenschr 138(30): 1533-1538
Mutters, N.T., R.J. Brooke, U. Frank, K. Heeg. 2013
Low risk of apparent transmission of vancomycin-resistant Enterococci from bacteraemic patients to hospitalized contacts.
Am J Infect Control 41(9): 778-781
Mutters, N.T., U. Frank. 2013
Sources of systematic errors in the epidemiology of vancomycin-resistant enterococci.
Infection 41(2): 305-310
Mutters, N.T., V. Mersch-Sundermann, R. Mutters, C. Brandt, W. Schneider-Brachert, U. Frank. 2013
Control of th Spread of Vancomycin-Resistant Enterococci in Hospitals: Epidemiology and Clinical Relevance.
Dtsch Arztebl Int 110(43): 725-731
Mutters, N.T., S. Stoffels, C. Eisenbach, S. Zimmermann. 2013
Ischaemic intestinal perforation complicated by Clostridium perfringens sepsis in a diabetic patient.
Infection 41: 1033-1035
Over, B., S. Ziegler, S. Foermer, A.N.R. Weber, K.A. Bode, K. Heeg, I. Bekeredjian-Ding. 2013
IRAK4 turns IL-10+ phospho-FOXO+ monocytes into pro-inflammatory cells by suppression of protein kinase B.
Eur J Immunol 43: 1630-1642
Parcina, M., M.A. Miranda-Garcia, S. Durlanik, S. Ziegler, B. Over, P. Georg, S. Foermer, S. Ammann, D. Hilmi, K.-J. Weber, M. Schiller, K. Heeg, W. Schneider-Brachert, F. Götz, I. Bekeredjian-Ding. 2013
Pathogen-Triggered Activation of Plasmacytoid Dendritic Cells Induces IL-10-Producing B Cells in Response to Staphylococcus aureus.
J Immunol 190(4): 1591-1602
Perovic, S., A. Perovic, L. Erdinger, H. Hollert. 2013
Assessment of the mutagenic potential of skadar lake sediments using the Salmonella microsomal assay.
Arch Biol Sci (Belgrade) 65(3): 1189-1194
Schneeberg, A., H. Neubauer, G. Schmoock, S. Baier, J. Harlizius, H. Nienhoff, K. Brase, S. Zimmermann, C.Seyboldt. 2013
Clostridium difficile Genotypes in Piglet Populations in Germany.
J Clin Microbiol 51(11): 3796-3803
Scholz, T., C.L. Heyl, D. Bernardi, S. Zimmermann, L. Kattner, C.D. Klein. 2013
Chemical, biochemical and microbiological properties of a brominated nitrovinylfuran with broad-spectrum antibacterial activity.
Bioorg. Med. Chem. 21: 795-804
Steinebrunner, N., C. Sandig, S. Zimmermann, W. Stremmel, C. Eisenbach, A. Mischnik. 2013
Salmonella enterica serovar Minnesota urosepsis in a patient with Crohn's disease in the absence of recent or curent gastrointestinal symptoms.
J Med Microbiol 62: 1360-1362
Suda, A.J., M. Kommerell, H.K. Geiss, I. Burckhardt, S. Zimmermann, F. Zeifang, B. Lehner. 2013
Prosthetic infection: Improvement of diagnostic procedures using 16S ribosomal deoxyribonucleic acid polymerase chain.
International Orthopaedics (SICOT) 37: 2515-2521
Ziegler, S., M.E. Eberle, S.J. Wölfle, K. Heeg, I. Bekeredjian-Ding. 2013
Bifunctional Oligodeoxynucleotide/AntagomiR Constructs: Evaluation of aNew Tool for MicroRNA Silencing.
Nucleic Acid Therapeutics 23: 427-434
Zimmermann, S., E. Hadaschik, A. Dalpke, J. Hassel, D. Ajzenberg, K. Tenner-Racz, N. Lehners, A. Kapaun, P. Schnitzler. 2013
Varicella-like cutaneous toxoplasmosis in a patient with aplastic anemia.
J Clin Microbiol 51(4): 1341-1344
Publikationen 2012
Bekeredjian-Ding, I., S. Foermer, C.J. Kirschning, M. Parcina, K. Heeg. 2012
Poke Weed Mitogen Requires Toll-like Receptor Ligands for Proliferative Activity in Human and Murine B Lymphocytes.
PLoS ONE 7(1): e29806. doi:10.1371/journal.pone.0029806
Dalpke, A.H., M. Helm. 2012
RNA mediated Toll-like receptor stimulation in health and disease.
RNA Biol 9(6): 828-842
Dalpke, A.H., M. Hofko, S. Zimmermann. 2012
Comparison of the BD MAX MRSA Assay and the BD GeneOhm MRSA Achromopeptidase Assay for the Detection of Methicillin-Resistant Staphylococcus aureus against Direct and Enriched Culture Techniques in Clinical Specimens.
J Clin Microbiol 50(10): 3365-3367
Eberle, M.E., A.H. Dalpke. 2012
Dectin-1 Stimulation Induces Seppressor of Cytokine Signaling 1, Thereby Modulating TLR Signaling and T Cell Responses.
J Immunol 188(11): 5644-5654
Eigenbrod, T., L. Franchi, R. Munoz-Planillo, C.J. Kirschning, M.A. Freudenberg, G. Nunez, A. Dalpke. 2012
Bacterial RNA Mediates Activation of Caspase-1 and IL-1ß Release Independently of TLRs 3, 7, 9 and TRIF but Is Dependent on UNC93B.
J Immunol 189: 328-336
Gehrig, S., M.E. Eberle,F. Botschen, K. Rimbach, F. Eberle, T. Eigenbrod, S. Kaiser, W.M. Holmes, V.A. Erdmann, M. Sprinzl, G. Bec, G. Keith, A.H. Dalpke*, M. Helm*. 2012
Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity.
J Exp Med 209(2): 225-233 *equal contribution
Ginter, T., C. Bier, S.K. Knauer, K. Sughra, D. Hildebrand, T. Münz, T. Liebe, R. Heller, A. Henke, R.H. Stauber, W. Reichardt, J.A. Schmid, K.F. Kubatzky, T. Heinzel, O.H. Krämer. 2012
Histone deacetylase inhibitors block IFNy-induced STAT1 phosphorylation.
Cell Signal 24(7): 1453-1460
Hidmark, A., A.v. Saint Paul, A.H. Dalpke. 2012
Cutting Edge: TLR13 Is a Receptor for Bacterial RNA.
J Immunol 189: 2717-2721
Hildebrand, D., A. Sähr, S.J. Wölfle, K. Heeg*, K.F. Kubatzky*. 2012
Regulation of Toll-like receptor 4-mediated immune responses through Pasteurella multocida toxin-induced G protein signalling.
Cell Communication and Signaling 10(22): 1-15 *equal contribution
Jennemann, R., M. Rabionet, K. Gorgas, S. Epstein, A. Dalpke, U. Rothermel, A. Bayerle, F. van der Hoeven, S. Irmgrund, J. Kirsch, W. Nickel, K. Willecke, H. Riezmann, H.-J. Gröne, R. Sandhoff. 2012
Loss of ceramide synthase 3 causes lethal skin barrier disruption.
Hum Mol Genet 21(3): 586-608
Kaier, K., N.T. Mutters, U. Frank. 2012
Bed occupancy rates and hospital-acquired infections - should beds be kept empty?
Clin Micribiol Infect 18(10): 941-945
Kaier, K., C. Wilson, M. Hilscher, H. Wollersheim, A. Huis, M. Borg, E. Scicluna, M.-L. Lambert, M. Palomar, E. Tacconelli, F. DeAngelis, M. Schumacher, M. Wolkewitz, E.-M. Kleissle, U. Frank. 2012
Implementing strategic bundles for infection prevention and management.
Infection 40(2): 225-228
Klein*, S., S. Zimmermann*, C. Köhler, A. Mischnik, W. Alle, K. Bode. 2012
Integration of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in blood culture diagnostics: a fast and effective approach.
J Med Microbiol 61: 323-331 *equal contribution
Knezevic, J., D. Pavlinic, W.A. Rose, C.A. Leifer, K. Bendelja, J. Gabrilovac, M. Parcina, G. Lauc, A.V. Kubarenko, B. Petricevic, D.Vrbanec, L. Bulat-Kardum, I. Bekeredjian-Ding, J. Pavelic, Z. Dembic, A.N. Weber. 2012
Heterozygous carriage of a dysfunctional TLR9 allele affects CPG-oligonucleotide responses in B cells.
J Biol Chem 287: 24544-24553
Kubatzky, K.F. 2012
Pasteurella Multocida and Immune Cells.
Curr Top Microbiol Immunol 361: 53-72
Lehner, B., M. Akbar, C. Rehnitz, G.W. Omlor, U. Dapunt, I. Burkhardt. 2012
Standards der mikrobiologischen Diagnostik der Spondylodiszitis.
Orthopädie 41: 702-710
Louis-Dit-Sully, C., K.F. Kubatzky, J.A. Lindquist, C. Blattner, O. Janssen, W.W. Schamel. 2012
Meeting report signal transduction meets systems biology.
Cell Commun Signal 10: 11
Mischnik, A., T. Dahme, R. Bekeredjian, S. Zimmermann. 2012
Haemophilia-associated Yersinia pseudotuberculosis serotype O:1 septicaemia: the role of iron.
J Med Microbiol. 61: 157-159
Mischnik, A., M. Mieth, C.J. Busch, S. Hofer, S. Zimmermann. 2012
First evaluation of PREVI Isola automated specimen inoculation for wound swab samples compared to manual inoculation in a routine laboratory. A cost-effective and accurate approach.
J Clin Microbiol 50: 2732-2736
Mutters, N.T. 2012
Infektiologie: Konkurrenzloses Standardwerk.
Dtsch Arztebl 109/31-32: A1560
Perovic, A., S. Perovic, L. Erdinger, H. Hollert. 2012
Assessment of the genotoxic potential of lake skadar sediments using ames test and comet assay on the fish cell line RTL-W1.
Arch Biol Sci Belgrade 64(1): 249-256
Reipschlaeger, S., K. Kubatzky, S. Taromi, M. Burger, J. Orth, K. Aktories, G. Schmidt. 2012
Toxin-induced RhoA activity mediates CCL1-triggered STAT signaling.
J Biol Chem 287: 11183-11194
Sangaré, L., A.K. Nikiéma, S. Zimmermann, I. Sanou, M. Congo-Ouédraogu, A. Diabaté, S. Diandé, P.I. Guissou. 2012
Campylobacter spp. epidemiology and antimicrobial susceptibility in a developing country, Burkina Faso (West Africa).
Afr J clin exper microbiol 13(2): 106-111
Schiller, M., M. Parcina, P. Heyder, S. Foermer, J. Ostrop, A. Leo, K. Heeg, H.M. Lorenz, I. Bekeredjian-Ding. 2012
Induction of Type I IFN Is a Physiological Reaction to Apoptotic Cell-Derived Membrane Microparticles.
J Immunol 189: 1747-1756
Strebovsky, J., A.H. Dalpke. 2012
SOCS
In: Encyclopedia of Signaling Molecules. Choi, Sangdun (Ed.), Springer New York, part20, 1753-1759, ISBN 978-1-4419-0460-7 (print)
Strebovsky, J., P. Walker, A.H. Dalpke. 2012
Suppressor of cytokine signaling proteins as regulators of innate immune signaling.
Front Biosci 17: 1627-1639
Stutz, A., H. Kessler, M.E. Kaschel, M. Meissner, A.H. Dalpke. 2012
Cell invasion and strain dependent induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii.
Immunobiol 217: 28-36
Wetterauer, B., M. Ricking, J.C. Otte, A.V. Hallare, A. Rastall, L. Erdinger, J. Schwarzbauer, T. Braunbeck, H. Hollert. 2012
Toxicity, dioxin-like activities,and endocrine effects of DDT metabolites - DDA, DDMU, DDMS, and DDCN.
Environ Sci Pollut Res 19: 403-415
Zeitvogel, J., A. Dalpke, B. Elz-Vesper, M. Kracht, O. Dittrich-Breiholz, T. Werfel, M. Wittmann. 2012
Human primary keratinoctes show a restricted ability to up-regulate Suppressor of Cytokine Signaling (SOCS)3 compared to autologous macrophages.
J Biol Chem : Epub ahead of priniting PMID: 22294695
Publikationen 2011
Binder, M., F. Eberle, S. Seitz, N. Mücke, C.M. Hüber, N. Kiani, L. Kaderali, V. Lohmann, A. Dalpke, R. Bartenschlager. 2011
Length-Dependent and 5'-Triphosphate-Independent Recognition of Double-Stranded RNA by Retinoic Acid Unducible Gene I.
J Biol Chem 286(31): 27278-27287
Bode, K.A., A.H. Dalpke. 2011
HDAC inhibitors block innate immunity. (Comment)
Blood 117(4): 1102-1103
Burckhardt, I., S. Zimmermann. 2011
Streptococcus pneumoniae in Urinary Tracts of Children with Chronic Kidney Disease.
Emerging Infectious Diseases 17(1): 120-122
Burckhardt, I., S. Zimmermann. 2011
Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry To Detect Carbapenem Resistance within 1 to 2.5 Hours.
J Clin Microbiol 49(9): 3321-3324
Ehlting, C., N. Ronkina, O. Böhmer, U. Albrecht, K.A. Bode, K.S. Lang, A. Kotlyarov, D. Radzioch, M. Gaestel, D. Häussinger, J.G. Bode.2011
Distinct functions of the mapkap kinases MK2 and MK3: MK2 mediates LPS-induced STAT3 activation by preventing negative regulatory effects of MK3.
J Biol Chem 286(27): 24113-24124
Erdinger, L., H. Hollert, P. Eckl. 2011
Aral Sea: An Ecological Disaster Zone with Impact on Human Health.
In: Encyclopedia of Environmental Health, Five-Volume Set, 1st Edition
Elsevier Science, ISBN 9780444522733
Erikson, E., T. Adam, S. Schmidt, J. Lehmann-Koch, B. Over, C. Goffinet, C. Harter, I. Bekeredjian-Ding, S. Sertel, F. Lasitschka, O.T. Keppler. 2011
In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humans.
PNAS: P Natl Acad Sci USA 108(33): 13688-13693
Haas, J., I. Bekeredjian-Ding, M. Milkova, B. Balint, A. Schwarz, M. Korporal, S. Jarius, B. Fritz, H.-M. Lorenz, B. Wildemann. 2011
B cells undergo unique compartmentalized redistribution in multiple sclerosis.
J Autoimmun 37(4): 289-299
Hildebrand, D., K. Heeg, K.F. Kubatzky. 2010
Pasteurella multocida Toxin-stimulated osteoclast differentiation is B cell dependent.
Infect Immun 79: 220-228
Hug, A., A. Liesz, B. Muerle, W. Zhou, J. Ehrenheim, A. Lorenz, A. Dalpke, R. Veltkamp. 2011
Reduced Efficacy of Circulating Costimulatory Cells After Focal Cerebral Ischemia.
Stroke 42(12): 3580-3586
Hug, A., B. Mürle, A. Dalpke, M. Zorn, A. Liesz, R. Veltkamp. 2011
Usefullness of Serum Procalcitonin Levels for the early Diagnosis of Stroke associated Respiratory Tract Infections.
Neurocrit Care 14(3): 416-422
Illanes, S., A. Liesz, L. Sun, A. Dalpke, M. Zorn, R. Veltkamp. 2011
Hematoma size as major modulator of the cellular immune system after experimental intracerebral hemorrhage.
Neurosci Lett 490(3): 170-174
Kurz, J., F. Eberle, T. Graumann, M.-E. Kaschel, A. Sähr, F. Neumann, A.H. Dalpke, L. Erdinger. 2011
Inactivation of LPS and RNase A on photocatalytically active surfaces.
Chemosphere 84: 1188-1193
Liesz, A., W. Zhou, E. Mracsko, S. Karcher, H. Bauer, S. Schwarting, L. Sun, D. Bruder, S. Stegemann, A. Cerwenka, C. Sommer, A.H. Dalpke, R. Veltkamp. 2011
Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke.
Brain 134(3): 704-720
Mackensen, F., S. Zimmermann, W. Alle, R. Max, E. Jakob, M.D. Becker, D. Thiemeyer. 2011
Difficulties of Interpreting Borrelia Serology in Patients with Uveitis.
Ocul Immunol Inflamm 19(4): 227-231
Mischnik, A., S. Zimmermann, I. Bekeredjian-Ding, M. Egermann. 2011
Relaps of posttraumatic osteomyelitis due to Clostridium celerecrescens.
Infection 39(5): 491-494
Mutters, N.T. 2011
Klinische Mikrobiologie und Hygiene: Rollenfindung zwischen Kommerz und Public Health.
Dtsch Ärztebl 108(25): A1426-A1427
Schmidt, L., M.G. Belvisi, K.A. Bode, J. Bauer, C. Schmidt, M.-T. Suchy, D. Tsikas, J. Scheuerer, F. Lasitschka, H.-J. Gröne, A.H. Dalpke. 2011
Bronchial Epithelial Cell-Derived Prostaglandin E2 Dampens the Reactivity of Dendritic Cells.
J Immunol 186(4): 2095-2105
Strebovsky, J., P. Walker, R. Lang, A.H. Dalpke. 2011
Suppressor of cytokine signaling 1 (SOCS1) limits NF(kappa)B signaling by decreasing p65 stability within the cell nucleus.
FASEB J 25(3): 863-874
Thomas, B.C., S. Zimmermann, H.-E. Völcker, G.U. Auffarth, S. Dithmar. 2011
Severe Arthrographis kalrae Keratomycosis in an Immunocompetent Patient.
Cornea 30: 364-366
Woelfle, S., J. Strebovsky, H. Bartz, A. Sähr, C. Arnold, C. Kaiser, A. Dalpke, K. Heeg. 2011
PD-L1 expression on tolerogenic APCs is controlled by STAT-3.
Eur J Immunol 41: 413-424
Wölz, J., K. Grosshans, G. Streck, T. Schulze, A. Rastall, L. Erdinger, W. Brack, M. Fleig, D. Kühlers, T. Braunbeck, H. Hollert. 2011
Estrogen receptor mediated activity in bankside groundwater, with flood suspended particulate matter and Floodplain soil - An Approach combining tracer substance, bioassay and target analysis.
Chemosphere 85: 717-723
Zhou, Z., J. Duerr, B. Johannesson, S.C. Schubert, D. Treis, M. Harm, S.Y. Graeber, A. Dalpke, C. Schultz, M.A. Mall. 2011
The ßENaC-overexpressing mouse as a model of cystic fibrosis lung disease.
Journal of Cystic Fibrosis 10(Suppl 2): S172-S182
Publikationen 2010
Brockmann, S., I. Piecholowski, O. Bock-Hensley, C. Winter, R. Oehme, S. Zimmermann, K. Hartelt, E. Luge, K. Nockler, T. Schneider, K. Stark, A. Jansen. 2010
Outbreak of leptospirosis among triathlon participants in Germany, 2006.
BMC Infect Dis 10: 91 (5 pages)
Burckhardt, I., F. Burckhardt, M. van der Linden, C. Heeg, R.R. Reinert. 2010
Risk factor analysis for pneumococcal meningitis in adults with invasive pneumococcal infection.
Epidemiol Infect 138(9): 1353-1358
Dalpke, A.H. 2010
Mikrobiologische und immunologische Konzepte als Grundlage zur Bewertung von Impfungen.
Präv Gesundheitsf 5: 33-37
Dalpke, A.H. 2010
Impfungen - neue Erkenntnisse aus der Grundlagenforschung
MMW Fortschr Med 152/2: 42-46
Eckerle, I., S. Zimmermann, A. Kapaun, T. Junghanss. 2010
Salmonella enterica Serovar Virchow Bacteremia Presenting as Typhoid-Like Illness in an Immunocompetent Patient.
J Clin Microbiol 48(7): 2643-2644
Fritz, S., T. Hackert, W. Hartwig, F. Rossmanith, O. Strobel, L. Schneider, K. Will-Schweiger, M. Kommerell, M.W. Büchler, J. Werner. 2010
Bacterial translocation and infected pancreatic necrosis in acute necrotizing pancreatitis derives from small bowel rather than from colon.
American Journal of Surgery 200: 111-117
Fürstenberg, C.H., B. Wiedenhöfer, C. Putz, I. Burckhardt, S. Gantz, K. Kleinschmidt, K. Schröder. 2010
Mit Gentamicin oder Levofloxacin gesättigter Kollagenhydroxyapatit (Healos®).
[Collagen hydroxyapatite (Healos) saturated with gentamicin or levofloxacin. In vitro antimicrobial effectiveness - a pilot study]
Orthopäde 39: 437-443
Gündogdu, M., H. Liu, D. Metzdorf, D. Hildebrand, M. Aigner, K. Aktories, K. Heeg, K.F. Kubatzky. 2010
The haematopoitic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression.
Mol cancer 9: 225 (13 pages)
Hildebrand, D., P. Walker, A. Dalpke, K. Heeg, K.F. Kubatzky. 2010
Pasteurella multocida Toxin-induced Pim-1 expression disrupts suppressor of cytokine signalling (SOCS)-1 activity.
Cell Microbiol 12(12): 1732-1745
Kristen, A.V., S. Zimmermann, B.M. Helmke, W. Hosch, H.A. Katus, F.J. Meyer. 2010
60-jährige Patientin mit Raumforderung im rechten Lungenoberlappen nach Herztransplantation.
Internist 51: 207-212
Kubarenko, A.V., S. Ranjan, A. Rautanen, T.C. Mills, S. Wong, F. Vannberg, M. Neumaier, I. Bekeredjian-Ding, A.V. Hill, P. Ahmad-Nejad, A.N. Weber. 2010
A naturally occurring variant in human TLR9, P99L, is associated with loss of CpG oligonucleotide responsiveness.
J Biol Chem 285: 36486-36494
Mackensen, F., M. Becker, S. Zimmermann. 2010
Tuberculous Uveitis.
Ophthalmology 117(2): 401-402. Letters to the Editor
Preuss, I., D. Hildebrand, J.H. Orth, K. Aktories, K.F. Kubatzky. 2010
Pasteurella multocida toxin is a potent activator of anti-apoptotic signalling pathways.
Cell Microbiol 12(8): 1174-1185
Salvenmoser, S., M.J. Seidler, A. Dalpke, F.M. Müller. 2010
Effects of caspofungin, Candida albicans and Aspergillus fumigatus on toll-like receptor 9 of GM-CSF-stimulated PMNs.
FEMS Immunol Med Microbiol 60:74-77
Seifert, H., A. Dalhoff et PRISMA Study Group. 2010
German multicentre survey of the antibiotic susceptibility of Bacteroides fragilis group an Prevotella species isolated from intra-abdominal infections: results from the PRISMA study.
J Antimicrob Chemother 65 : 2405-2410
Thomas, B.C., S. Zimmermann, H.-E. Völcker, G.U. Auffarth, S. Dithmar. 2010
Severe Arthrographis kalrae Keratomycosis in an Immunocompetent Patient.
Cornea 30(3): 364-366
Ulrich, K., S. Wölfle, A. Mayer, K. Heeg, T. Braunbeck, L. Erdinger, H. Bartz. 2010
Extractable organic matter of Standard Reference Material 1649a influences immunological response induced by pathogen-associated molecular patterns.
Environ Sci Pollut Res 17: 1257-1267
Wendt, C., N.L. Havill, K.C. Chapin, J.M. Boyce, R. Dickenson, U. Eigner, S. Schütt, A.M. Fahr. 2010
Evaluation of a new selective medium, BD BBL CHROMagar MRSA II, for detection of methicillin-resistant Staphylococcus aureus in different specimens.
J Clin Microbiol 48(6): 2223-2227
Wendt, C., S. Schütt. 2010
Nachweis von Klebsiella pneumoniae-Carbapenemase in einem deutschen Krankenhaus.
Hyg Med 35(1/2): 21-25
Wendt, C., S. Schütt, A.H. Dalpke, M. Konrad, M. Mieth, B. Trierweiler-Hauke, M.A. Weigand, S. Zimmermann, K. Biehler, D. Jonas. 2010
First outbreak of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae in Germany.
Eur J Clin Microbiol Infect Dis 29(5): 563-565
Wensing, A., S. Zimmermann, K. Geider. 2010
Identification of the corn pathogen Pantoea stewartii by Mass Spectrometry of whole cell extracts and its detection with novel PCR primers.
Appl Environ Microbiol 76: 6248-6256
Zhou, Z., J. Duerr, B. Johannesson, S.C. Schubert, D. Treis, M. Harm, S.Y. Graeber, A. Dalpke, C. Schultz, M.A. Mall. 2010
The ßENaC-overexpressing mouse as a model of cystic fibrosis lung disease.
Journal of Cystic Fibrosis 9: Suppl. 3, S1-S11
Publikationen 2009
Bekeredjian-Ding, I., G. Jego. 2009
Toll-like Receptors - Sentries in the B-Cell Response.
Immunology 128: 311-323 Invited Review
Bekeredjian-Ding, I., M. Schäfer, E. Hartmann, R. Pries, M. Parcina, P. Schneider, T. Giese, S. Endres, B. Wollenberg, G. Hartmann. 2009
Tumour-derived prostaglandin E2 and transforming growth factor-β synergize to inhibit plasmacytoid dendritic cell-derived interferon-α.
Immunology 128: 439-450
Berger, M., A. Ablasser, S. Kim, I. Bekeredjian-Ding, T. Giese, S. Endres, V. Hornung, G. Hartmann. 2009
TLR8-driven IL-12-dependent Reciprocal and Synergistic Activation of NK Cells an Monocytes by Immunostimulatory RNA.
J Immunother 32(3): 262-271
Bock-Hensley, O., C. Wendt. 2009
MRSA im Pflegeheim. Was müssen Sie im Umgang mit dem Problemkeim beachten?
[Methicillin-resistant Staphylococcus aureus in nursing homes]
MMW Fortschr Med. 39: 41-46. German
Bode, K.A., F. Schmitz, L. Vargas, K. Heeg, A.H. Dalpke. 2009
Kinetic of RelA activation controls magnitude of Toll-like receptor mediatied IL-12p40 induction.
J Immunol 182(4): 2176-2184
Cookson, B., E. Mathai, B. Allegranzi, C.L. Pessoa-Silva, S. Bagheri Nejad, A. Schneider, C. Tschopp, C. Wendt, D. Pittet. 2009
Comparison of national and subnational guidelines for hand hygiene.
J Hosp Infect 72: 202-210
Dalpke, A.H. 2009
Immunologische Rationalen von Impfungen.
[Immunological basics of vaccination.]
Dtsch Med Wochenschr 134: 561-564. German
Eberle, F., M. Sirin, M. Binder, A.H. Dalpke. 2009
Bacterial RNA is recognized by different sets of immunoreceptors.
Eur J Immunol 39: 2537-2547
Heyder, P., I. Bekeredjian-Ding, S. Krienke, H.M. Lorenz, M. Schiller. 2009
Cells induced to undergo apo in the presens of the caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone stimulate Mo derived phagocytes to secrete proinflammatory cytokines.
Autoimmunity 42(4): 328-330
Hug, A., A. Dalpke, N. Wieczorek, T. Giese, A. Lorenz, G. Auffarth, A. Liesz, R. Veltkamp. 2009
Infarct Volume is a Major Determiner of Post-Stroke Immune Cell Function an Susceptibility to Infection.
Stroke 40(10): 3226-3232
Koelsche, C., J. Strebovsky, A. Baetz, A.H. Dalpke. 2009
Structural and functional analysis of a nuclear localization signal (NLS) in SOCS1.
Mol Immunol 46(13): 2474-2480
Krautter, U., M. Mory, C. Mogler, M. Schmaus, S. Zimmermann, K. Klemm, J. Debus, S. Oertel. 2009
Fatal Clostridium septicum Infection in a Patient with Non-Hodgkin's Lymphoma Undergoing Multimodal Oncologic Therapy.
Onkologie 32: 115-118
Kresken, M., E. Leitner, J. Brauers, H.K. Geiss, E. Halle, C. von Eiff, G. Peters, H. Seifert. 2009
Susceptibility of common aerobic pathogens to tigecycline: results of a surveillance study in Germany.
Eur J Clin Microbiol Infect Dis 28: 83-90
Liesz, A., S. Hagmann, C. Zschoche, J. Adamek, W. Zhou, L. Sun, A. Hug, M. Zorn, A. Dalpke, P. Nawroth, R. Veltkamp. 2009
The Spectrum of Systemic Immune Alterations After Murine Focal Ischemia, Immunodepression Versus Immunomodulation.
Stroke 40: 2849-2858
Mätz-Rensing, K., J. Winkelmann, T. Becker, I. Burckhardt, M. van der Linden, S. Köndgen, F. Leendertz, F.J. Kaup. 2009
Outbreak of Streptococcus equi subsp. zooepidemicus infection in a group of rhesus monkeys (Macaca mulatta).
J Med Primatol 38(5): 328-334
Meesmann, H.M., M. Parcina, H.M. Lorenz, N. Blank, M. Schiller. 2009
Apo mterial as a trigger for inflammation in systemic lupus erythematosus.
Autoimmunity 42(4): 251-253
Olbert, P.J., A.J. Schrader, C. Simon, A. Dalpke, P. Barth, R. Hofmann, A. Hegele. 2009
In Vitro and in Vivo Effects of CpG-Oligodeoxynucleotides (CpG-ODN) on Murine Transitional Cell Carcinoma and on the Native Murine Urinary Bladder Wall.
Anticancer Res. 29(6): 2067-2076
Parcina, M., M. Schiller, A. Gierschke, K. Heeg, I. Bekeredjian-Ding. 2009
PDC expression CD36, CD61 and IL-10 may contribute to propagation of immune tolerance.
Autoimmunity 42(4): 353-355
Peter, M.E., A.V. Kubarenko, A.N.R. Weber, A.H. Dalpke. 2009
Identification of an N-Terminal Recognition Site in TLR9 That Contributes to CpG-DNA-Mediated Receptor Activation.
J Immunol 182(12): 7690-7697
Rosenhagen, M., R. Feldhues, J. Schmidt, T. Hoppe-Tichy, H.K. Geiss. 2009
A Risk Profile for Invasive Aspergillosis in Liver Transplant Recipients.
Infection 37: 313-319
Swoboda, S., L. Helbig, M. Kommerell, H.G. Simank, F. Kees, H.K. Geiss, T. Hoppe-Tichy, K. Schröder. 2009
Bone tissue and plasma concentrations of linezolid and vancomycin in rabbits with prosthesis-related infection due to MRSA
Pharmazie 64(6): 407-409
Wilms, M.C., S. Stanzel, R.R. Reinert, I. Burckhardt. 2009
Effects of preincubation temperature on the detection of fastidious organisms in delayed-entry samples in the BacT/ALERT 3D blood culture system.
J Micro Meth 79: 194-198
Württemberger, M., C. Wendt. 2009
Hygienebeauftragte in der Pflege - ein Konzept für die Praxis.
Hyg Med 34(10): 381-385
Zimmermann, S., H. Moll, W. Solbach, C.G.K. Lüder. 2009
Meeting Report IFoLeish-2008: Current Status and Future Challenges in Leishmania Research and Leishmaniasis.
Protist 160: 151-158
Publikationen 2008
Baetz, A., C. Koelsche, J. Strebovsky, K. Heeg, A.H. Dalpke. 2008
Identification of a nuclear localization signal in suppressor of cytokine signaling 1.
FASEB J 22: 4296-4305
Bekeredjian-Ding, I., A. Doster, M. Schiller, P. Heyder, H.-M. Lorenz, B. Schraven, U. Bommhardt, K. Heeg. 2008
TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM+ B Cells.
J Immunol 181: 8267-8277
Chiron, D., I. Bekeredjian-Ding, C. Pellat-Deceunynck, R. Bataille, G. Jego. 2008
Toll-like receptors: lessons to learn from normal and malignant human B cells.
Blood 112(6): 2205-2213
Dalpke, A., K. Heeg, H. Bartz, A. Baetz. 2008
Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins.
Immunobiology 213: 225-235
Eberle, F., K. Gießler, C. Deck, K. Heeg, M. Peter, C. Richert, A.H. Dalpke. 2008
Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference.
Journal of Immunology 180: 3229-3237
Fritz, S., W. Hartwig, R. Lehmann, K. Will-Schweiger, M. Kommerell, T. Hackert, L. Schneider, M.W. Büchler, J. Werner. 2008
Prophylactic antibiotic treatment is superior to therapy on-demand in experimental necrotising pancreatitis.
Critical Care 12(6): 195-204
Fueller, F., K.F. Kubatzky. 2008
The small GTPase RhoH is an atypical regulator of haematopoietic cells.
Cell Commun Signal 6(1): 6
Heeg, K. 2008
The Innate Immune System
In: The Hypothalamus-Pituitary-Adrenal Axis, Neuroimmune Biology, Volume 7
Elsevier ISBN 978-0-444-53040-0
Heeg, K., A. Dalpke, M. Peter, S. Zimmermann. 2008
Structural requirements for uptake and recognition of CpG oligonucleotides.
Int J Med Microbiol 298(33): 33-38
Hofer, S., C. Eisenbach, I.K. Lukic, L. Schneider, K. Bode, M. Brueckmann, S. Mautner, M.N. Wente, J. Encke, J. Werner, A.H. Dalpke, W. Stremmel, P.P. Nawroth, E. Martin, P.H. Krammer, A. Bierhaus, M.A. Weigand. 2008
Pharmacologic cholinesterase inhibition improves survival in experimental sepsis.
Crit Care Med 36(2): 404-408
Jappe, U., D. Heuck, B. Strommenger, C. Wendt, G. Werner, D. Altmann, W. Witte. 2008
Staphylococcus aureus in dermatology outpatients with special emphasis on community-associated methicillin-resistant strains.
J Invest Dematol 128(11): 2655-2664
Knorr, B., H. Maul, P. Schnitzler. 2008
Prevalence of hepatitis B virus infection among women at reproductive age at a German university hospital.
Journal of Clinical Virology 42: 422-424
Lorenz, H.M., A.H. Dalpke, A. Deboben, A.D. Ho, A. Greiner, M. Jung, C. Fiehn. 2008
Mycobacterium kansasii Tenosynovitis in a Rheumatoid Arthritis Patient With long-Term Therapeutic Immunosuppression.
Arthritis & Rheumatism/Arthritis Care Res 59(6): 900-903
Mackensen, F., M.D. Becker, U. Wiehler, R. Max, A. Dalpke, S. Zimmermann. 2008
QuantiFERON TB-Gold - A new test strengthening long suspected tuberculous involvement in serpiginous-like chorioiditis.
Am J Ophthalmol 146(5): 761-766
Mayer, A.K., H. Bartz, F. Fey, L.M. Schmidt, A.H. Dalpke. 2008
Airway epithelial cells modify innate and adaptive immune responses by including an anti-inflammatory microenvironment.
Eur J Immunol 38(6): 1689-1699
Mrabet-Dahbi, S., A.H. Dalpke, M. Niebuhr, M. Frey, M. Niehbuhr, C. Draing, S. Brand, K. Heeg, T. Werfel, H. Renz. 2008
The heterozygous TLR-2 R753Q mutation in atopic dermatitis: Effect on pro-inflammatory chemokine production, TLR expression and TH1 responses.
J Allergy Clin Immun 121(4): 1013-1019
Oberdorfer, K., G. Müssigbrodt, C. Wendt. 2008
Genetic diversity of Legionella pneumophila in hospital water systems.
Int J Hyg Envir Heal 211(1-2): 172-178
Parcina, M., C. Wendt, F. Goetz, R. Zawatzky, U. Zähringer, K. Heeg, I. Bekeredjian-Ding. 2008
Staphylococcus aureus-Induced Plasmacytoid Dendritic Cell Activation Is Based on an IgG-Mediated Memory Response.
J Immunol 181 (6): 3823-3833
Peter, M., K. Bode, G.B. Lipford, F. Eberle, K. Heeg, A.H. Dalpke. 2008
Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity.
Immunology 123: 118-128
Piehler, A.P., M. Hellum, J.J. Wenzel, E. Kaminski, K.B.F. Haug, P. Kierolf, W.E. Kaminski, 2008
The human ABC transporter pseudogene family: Evidence fro transcription and gene-pseudogene interference.
BMC Genomics 9: 165-177
Rüping, M.J., N. Albermann, F. Ebinger, I. Burckhardt, C. Beisel, C. Müller, J.J. Vehreschild, M. Kochanek, G. Fätkenheuer, C. Bangard, A.J. Ullmann, W. Herr, K. Kolbe, M. Hallek, O.A. Cornely. 2008
Posaconazole concentrations in the central nervous system.
J Antimicrob Chemoth 62: 1468-1470
Schiller, M., I. Bekeredjian-Ding, P. Heyder, N. Blank, A.D. Ho, H.M. Lorenz. 2008
Autoantigens are translocated into small apoptotic bodies during early stages of apoptosis.
Cell Death Differ 15: 183.191
Swoboda, S., M. Ober, C. Hainer, C. Lichtenstern, C. Seiler, C. Wendt, T. Hoppe-Tichy, M. Büchler, M.A. Weigand. 2008
Tigecycline for the treatment of patients with severe sepsis or septic shock: a drug use evaluation in a surgical intensive care unit.
J Antimicrob Chemoth 61(3): 729-733
Theiner, G., S. Rößner, A. Dalpke, K. Bode, T. Berger, A. Gessner, M. Lutz. 2008
TLR9 cooperates with TLR4 to increase IL-12 release by murine dendritic cells
Mol. Immunol. 45: 244-252
Zimmermann, S., A. Dalpke, K. Heeg. 2008
CpG oligonucleotides as adjuvant in therapeutic vaccines against parasitic infections.
Int J Med Microbiol 298(1-2): 39-44
Publikationen 2007
Baetz, A., S. Zimmermann, A.H. Dalpke. 2007
Microbial immune evasion employing suppressor of cytokine signaling (SOCS) proteins.
Inflammation & Allergy - Drug Targets 6(3): 160-167
Bekeredjian-Ding, I., S. Inamura, T. Giese, H. Moll, S. Endres, A. Sing, U. Zähringer, G. Hartmann. 2007
Staphylococcus aureus protein A triggers T cell-independent B cell proliferation by sensitizing B cells for TLR2 ligands.
Journal of Immunology 178: 2803-2812
Blümer, N., S. Sel, S. Virna, C.C. Patrascan, S. Zimmermann, U. Herz, H. Renz, H. Garn. 2007
Perinatal maternal application of Lactobacillus rhamnosus GG suppresses allergic airway inflammation in mouse offspring.
Clinical and Experimental Allergy 37: 348-357
Bode, K.A., K. Schroder, D.A. Hume, T. Ravasi, K. Heeg, M.J. Sweet, A.H. Dalpke. 2007
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment.
Immunology 122(4): 596-606
Dannewitz, B., S. Pohl, P. Eickholz, T.S. Kim. 2007
Clinical and microbiological effects of a combined mechanic-antibiotic therapy in subjects with Actinobacillus actinomycetemcomitans-associated periodontitis
Am J Dent 20(3): 153-156
Hagenah, G.C., T. Wündisch, E. Eckstein, S. Zimmermann, F. Holst, W. Grimm, A. Neubauer, M. Lohoff. 2007
[Sepsis-like disease in an immuncompromised patient with a travel history to Mallorca.]
Internist 48: 727-730 German
He, G., A. Patra, K. Siegmund, M. Peter, K. Heeg, A. Dalpke, C. Richert. 2007
Immunostimulatory CpG oligonucleotides form defined three-dimensional structures: Results from an NMR study.
ChemMedChem 2(4): 549-560
Heyder, P., I. Bekeredjian-Ding, M. Parcina, N. Blank, A.D. Ho, M. Herrmann, H.-M. Lorenz, K. Heeg, M. Schiller. 2007
Purified apoptotic bodies stimulate plasmacytoid dendritic cells to produceIFN-alpha. Brief Definitive Report
Autoimmunity 40(4): 331-332
Järve, A., J. Müller, K. Il-Han, K. Rohr, C. MacLean, G. Fricker, U. Massing, F. Eberle, A. Dalpke, R. Fischer, M.F. Trendelenburg, M. Helm. 2007
Surveillance of siRNA integrity by FRET imaging.
Nucleic Acids Res 35(18): e124
Knorr, B., U. Kessler, J. Pöschl, H. Fickenscher, O. Linderkamp. 2007
A haemophagocytic lymphohistiocytosis (HLH)-like picture following breastmilk transmitted cytomegalovirus infection in a preterm infant.
Scand J Infect Dis 39(2): 173-176
Mayer, A.K., A.H. Dalpke. 2007
Regulation of local immunity by airway epithelial cells.
Arch Immunol Ther Exp 55: 353-362
Mayer, A.K., M. Muehmer, J. Mages, K. Gueinzius, C. Hess, K. Heeg, R. Bals, R. Lang, A.H. Dalpke. 2007
Differential recognition of Toll-like receptor dependant microbial ligands in human bronchial epithelial cells: Implications for pattern recognition at non-sterile mucosal surfaces.
J Immunol 178(5): 3134-3142
Nguyen, T.H., T. Hoppe-Tichy, H.K. Geiss, A.C. Rastall, S. Swoboda, J. Schmidt, M.A. Wiegand. 2007
Factors influencing caspofungin plasma concentrations in patients of a surgical intensive care unit.
Journal of Antimicrobial Chemotherapy 60: 100-106
Orth, J.H., K. Aktories, K.F. Kubatzky. 2007
Modulation of host cell gene expression through activation of STAT transcription factors by Pasteurella multocida toxin.
J Biol Chem 282(5): 3050-3057
Schroder, K., M. Spille, A. Pilz, J. Lattin, K. Bode, K.M. Irvine, A.D. Burrows, T. Ravasi, H. Weighardt, K.J. Stacey, T. Decker, D.A. Hume, A.H. Dalpke, M.J. Sweet. 2007
Differential effects of CpG DNA on IFNb induction and STAT1 activation in murine macrophages versus dendritic cells: identification of a novel function for STAT1 in toll-like receptor signalling.
J Immunol 179(6): 3495-3502
Steppan, S., K. Kupfer, A. Mayer, M. Evans, G. Yamasaki, J.M. Greve, M.R. Eckart, D.J. Cassell. 2007
Genome Wide Expression Profiling of Human Peripheral Blood Mononuclear Cells Stimulated With BAY 50-4798, a Novel T Cell Selective Interleukin-2 Analog
J Immunother 30(2): 150-168
Swoboda, S., T. Hoppe-Tichy, H.K. Geiss, C. Hainer, T.H. Nguyen, H.P. Knaebel, M.A. Weigand. 2007
[Septic shock to vancomycin-resistant enterococci infection. Tigecycline monotherapy.]
Anaesthesist 56(2): 169-174 German
Swoboda, S., M. Ober, K. Anagnostakos, H.K. Geiss, M.A. Wiegand, T. Hoppe-Tichy. 2007
A simple isocratic HPLC assay to determine linezolid concentrations in different biomatrices for in vivo and in vitro studies.
Clin Chem Lab Med 45(8): 1019-1022
Tschachler, E., N. Brockmeyer, I. Effendy, H.K. Geiss, S. Harder, M. Hartmann, U. Jappe, A. Plettenberg, H. Rasokat, H. Reimann, P. Shah, M. Stücker, T.A. Wichelhaus, H. Schöfer. 2007
Streptococcal infections of the skin an mucous membranes.
J Dtsch Dermatol Ges 5(6): 527-532
Vonberg, R.P., I.F. Chaberny, A. Kola, F. Mattner, S. Borgmann, M. Dettenkofer, D. Jonas, A.M. Fahr, I. Klare, G. Werner, K. Weist, C. Wendt, P. Gastmeier. 2007
[Prevention and control of the spread of vancomycin-resistant enterococci: results of a workshop held by the German Society for Hygiene and Microbiology.]
Anaesthesist 56(2): 151-157
Wendt, C., S. Schinke, M. Württemberger, K. Oberdorfer, O. Bock-Hensley, H. von Baum. 2007
Value of whole-body washing with chlorhexidine for the eradication of methicillin-resistant Staphylococcus aureus: a randomized, placebo-controlled, double-blind clinical trial.
Infect Control Hosp Emidemiol 28(9): 1036-1043
Wiegand, I., H.K. Geiss, D. Mack, E. Stürenburg, H. Seifert. 2007
Detection of Extended-Spectrum Beta-Lactamase among Enterobacteriaceae by Use of Semiautomated Microbiology Systems and Manual Detection Procedures.
Journal of Clinical Microbiology 45(4): 1167-1174
Zimmermann, S., A. Dalpke. 2007
[Molecular biology-based methods for pathogen detection in endophthalmitis.]
Der Ophthalmologe 104(11): 940-946 German
Publikationen 2006
Bartz, H., N.M. Avalos, A. Baetz, K. Heeg, A.H. Dalpke. 2006
Blood 108 (13), 4102-4108
Bekeredjian-Ding, I., S.I. Roth, S. Gilles, T. Giese, A. Ablasser, V. Hornung, S. Endres, G. Hartmann. 2006
T cell-independent TLR-induced IL-12p70 production in primary human monocytes.
J. Immunol. 176: 7438-7446
Bock-Hensley, O., U. Niekusch, M. Klett, C. Wendt. 2006
Zahnhygiene in Altenheimen des Rhein-Neckar-Kreises und der Stadt Heidelberg - Ergebnisse einer Umfrage.
Hyg. Med. 31, 12-15
Bosch, K., L. Erdinger, F. Ingel, S. Khussainova, E. Utegenova, Bresgen, N.P.M. Eckl. 2006
Evaluation of the toxicological properties of ground- and surface-water samples from the Aral Sea Basin.
Sci Total Environ 374: 43-50
Dalpke, A.H., J. Frank, M. Peter, K. Heeg. 2006
Activation of Toll-Like Receptor 9 by DNA from Different Bacterial Species.
Infect. Immun. 74(2): 940-946
del Ray A., V. Renigunta, A.H. Dalpke, J. Leipziger, J.E. Matos, B. Robaye, M. Zuzarte, A. Kavelaars, P.J. Hanley. 2006
J. Biol. Chem. 281(46): 35147-55
Gunale, A., H. von Baum, C. Wendt. 2006
Survival of cephalosporin-resistant enterobacteriaceae on fingers.
Infect Cont Hosp Ep 27, 974-977
Harter, C., B. Schulze, H. Goldschmidt, A. Benner, H.K. Geiss, T. Hoppe-Tichy, A.D. Ho, G. Egerer. 2006
Piperacillin/tazobactam vs ceftazidime in the treatment of neutropenic fever in patients with acute leukemia or following autologous peripheral blood stem cell transplantation: a prospective randomized trial.
Bone Marrow Transpl 37, 373-379
Keiter, S., A. Rastall, T. Kosmehl, K. Wurm, L. Erdinger, T. Braunbeck, H. Hollert. 2006
Ecotoxicological assessment of sediment, suspended matter and water samples in the upper Danube River - A pilot study in search for the causes for the decline of fish catches.
Environmental Science and Pollution Research 13 (5), 308-319
Kola, A., I.F. Chaberny, F. Mattner, U. Reischl, R.P. Vonberg, K. Weist, C. Wendt, W. Witte, S. Ziesing, S. Suerbaum, P. Gastmeier. 2006
Control of methicillin-resistant S. aureus by active surveillance. Results of a workshop held by the Deutsche Gesellschaft für Hygiene und Mikrobiologie.
Anaesthesist 55, 778-783
Oberdorfer, K., S. Pohl, M. Frey, K. Heeg, C. Wendt. 2006
Evaluation of a single-locus real-time polymerase chain reaction as a screening test for specific detection of methicillin-resistant Staphylococcus aureus in ICU patients.
Eur J Clin Microbiol Infect Dis. 25, 657-663
Petersdorf, S., K. Oberdorfer, C. Wendt. 2006
Longitudinal Study of the Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus at a University Hospital.
J. Clin. Microbiol. 44 (12), 4297-4302
Rastall, A.C., D. Getting, J. Goddard, D.R. Roberts, L. Erdinger. 2006
A biomimetic approach to the detection and identification of estrogen receptor agonists in surface waters using semipermeable membrane devices (SPMDs) and bioassay-directed chemical analysis.
Environmental Science and Pollution Research 13 (4), 256-267
Seiler, T.-B., A.C. Rastall, E. Leist, L. Erdinger, T. Braunbeck, H. Hollert. 2006
Membrane Dialysis Extraction (MDE): A Novel Approach for Extracting Toxicologically Relevant Hydrophobic Organic Compounds from Soils and Sediments for Assessment in Biotests.
J. Soils & Sediments 6 (1), 20-29
Tietze, K., A. Dalpke, S. Morath, R. Mutters, K. Heeg, C. Nonnenmacher. 2006
Differences in innate immune responses upon stimulation with gram-positive and gram-negative bacteria.
J. Periodontol. Res. 41(5): 447-454
von Baum, H., M. Dettenkofer, A.M. Fahr, P. Heeg, C. Wendt. 2006
Konsensusempfehlungen Baden-Württemberg Umgang mit Patienten mit Glycopeptid-resistenten Enterokokken (GRE)/Vancomycin-resistenten Enterokokken (VRE)
Hyg. Med. 31, 30-32
Wendt, C., in Zusammenarbeit mit den Mitgliedern des Netzwerkes Zukunft Hygiene. 2006
Bereitstellung aktueller Informationen zur Infektionsprävention am Beispiel der (aviären) Influenza.
Hyg. Med. 31, 522-525
Wendt, C., O. Bock-Hensley, H. von Baum. 2006
Infection control in German nursing homes.
Am J Infect Control. 34, 426-429
Wildemann, B., H.K. Geiss, P. Schnitzler. 2006
Erregerdiagnostik.
In: B. Wildemann, P. Oschmann, H. Reiber: Neurologische Labordiagnostik.
Georg Thieme Verlag, Stuttgart, 59-68
Zimmermann, S., P.J. Murray, K. Heeg, A.H. Dalpke. 2006
Induction of Suppressor of Cytokine Signaling-1 (SOCS-1) by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN-g Signaling.
J. Immunol. 176(3): 1840-1847
Publikationen 2005
Bartz, H., C. Nonnenmacher, C. Bollmann, M. Kuhl, S. Zimmermann, K. Heeg, R. Mutters. 2005
Micromonas (Peptostreptococcus) micros: unusual case of prosthetic joint infection associated with dental procedures.
Int.J.Med.Microbiol. 294(7): 465-470
Brack, W., K. Schirmer, L. Erdinger, H. Hollert. 2005
Effect-directed analysis of mutagens and ethoxyresorufin-o-deethylase inducers in aquatic sediments.
Environ. Toxicol. Chem. 24: 2445-2458
Dalpke, A.H., M. Lehner, T. Hartung, K. Heeg. 2005
Differential effects of CpG-DNA in TLR-2/-4/-9 tolerance and cross-tolerance.
Immunology 116: 203-212
Erdinger, L., M. Dürr, K.A. Höpker. 2005
Correlations between mutagenic activity of organic extracts of airborne particulate matter, NOx and sulphur dioxide in southern Germany: results of a two-year study.
Environ. Sci. Pollut. Res. Int. 12: 10-20
Gabrio, T., S. Broser, L. Erdinger, A. Felder-Kennel, G. Fichtner, E. Haberle, T. Herrmann, H. Kirsch, B. Kouros, B. Link, V. Maisner, V. Mann, O. Papke, I. Piechotowski, E. Rzonca, K.H. Schick, M. Schrimpf, S. Schröder, K. Spoker-Maas, U. Weidner, J. Wuthe, I. Zollner, D. Zoltzer. 2005
Human biomonitoring investigations of organochlorine compounds - PCB, DDE, HCB, beta- and gamma-HCH, PCDD/PCDF, Dioxin-like PCB's and polybrominated biphenyl ethers. (German)
Gesundheitswesen 67: 302-311
Geiss, H.K., R. Feldhues, S. Niemann, O. Nolte, R. Rieker. 2005
Landouzy Septicemia (Sepsis Tuberculosa Acutissima) Due to Mycobacterium microti in an Immunocompetent Man
Infection 33(5-6): 393-396
Hegele, A., A. Dalpke, K. Heeg, P. Barth, Z. Varga, R. Hofmann, P. Olbert. 2005
Immunostimulatory CpG Oligonucleotides Reduce Tumor Burden after Intravesical Administration in an Orthotopic Murine Bladder Cancer Model.
Tumor Biol. 26: 274-280
Hocker, B., C. Wendt, A. Nahimana, B. Tönshoff, P.M. Hauser. 2005
Outbreak of Pneumocystis Pneumonia in Pediatric Renal Transplant Unit.
Emerg. Infect. Dis. 11: 330-332
Hollert, H., M. Dürr, R. Holtey-Weber, M. Islinger, W. Brack, H. Farber, L. Erdinger, T. Braunbeck. 2005
Endocrine disruption of water and sediment extracts in a non-radioactive dot blot/RNAse protection-assay using isolated hepatocytes of rainbow trout.
Environ. Sci. Pollut. Res. Int. 12, 347-360
Kamimura, M., C. Viedt, A. Dalpke, M.E. Rosenfeld, N. Mackmann, D.M. Cohen, E. Blessing, M. Preusch, C.M. Weber, J. Kreuzer, H.A. Katus, F. Bea. 2005
Interleukin-10 Suppresses Tissue Factor Expression in Lipopolysaccharide-Stimulated Macrophages via Inhibition of Egr-1 and a Serum Response Element/MEK-ERK1/2 Pathway.
Circ. Res. 97(4): 305-313
Kaufmann, A., B. Musset, S.H. Limberg, V. Renigunta, R. Sus, A.H. Dalpke, K. Heeg, B. Robaye, P.J. Hanley. 2005
"Host tissue damage" signal ATP promotes non-directional migraton and negatively regulates Toll-like receptor signaling in human monocytes.
J. Biol. Chem. 280(37): 32459-32467
Klotz, M., S. Zimmermann, S. Opper, K. Heeg, R. Mutters. 2005
Possible risk for re-colonization with methicillin-resistant Staphylococcus aureus (MRSA) by faecal transmission.
Int. J. Hyg. Environ. Health 208, 401-405
Mrabet-Dahbi, S., K. Breuer, M. Klotz, U. Herz, K. Heeg, T. Werfel, H. Renz. 2005
Deficiency in immunglobulin G2 antibodies against staphylococcal enterotoxin C1 defines a subgroup of patients with atopic dermatitis.
Clin. Exp. Allergy 35: 274-281.
Nolte, O., H. Haag, A. Zimmermann, H.K. Geiss. 2005
Staphylococcus aureus positive for Panton-Valentine leukocidin genes but susceptible to methicillin in patients with furuncles.
Eur. J. Clin. Microbiol. Infect. Dis. 24: 477-479
Nonnenmacher, C., A.H. Dalpke, J. Rochon, L. Flores-de-Jacoby, R. Mutters, K. Heeg. 2005
Real-Time polymerase chain reaction for detection and quantification of bacteria in periodontal diseased patients.
J. Periodontol. 76(9): 1542-1549
Ochs, B.G., M. Kommerell, H.K. Geiss, H.G. Simank. 2005
Improving microbiological diagnostics in septic orthopaedic surgery. Comparative study of patients receiving systemic antibiotic therapy. (German)
Orthopäde 34: 345-351
Ostendorf, T., A. Meinhold, C. Harter, H. Salwender, G. Egerer, H.K. Geiss, A.D. Ho. 2005
Chlorhexidine and silver-sulfadiazine coated central venous catheters in haematological patients - a double-blind, randomised, prospective, controlled trial.
Support Care Cancer 13: 993-1000
Schöfer, H, N. Brockmeyer, J. Dissemond, I. Effendy, S. Esser, H.K. Geiss, S. Harder, M. Hartmann, U. Jappe, A. Plettenberg, H. Reimann, P. Shah, E. Tschachler, T. Wichelhaus. 2005
Staphylokokken-Infektionen der Haut und Schleimhäute. Leitlinie der Deutschen Dermatologischen Gesellschaft (DDG), Arbeitsgemeinschaft für Dermatologische Infektiologie (ADI)
Chemother J 14: 67-73
Swoboda, S., S. Fritz, M.E. Martignoni, R.A. Feldhues, T. Hoppe-Tichy, M.W. Büchler, H.K. Geiss. 2005
Varying linezolid susceptibility of vancomycin-resistant Enterococcus faecium isolates during therapy: a case report.
J Antimicrob Chemother 56: 787-789
von Baum, H., J.F. Ober, C. Wendt, R.P. Wenzel, M.B. Edmond. 2005
Antibiotic-Resistant Bloodstream Infections in Hospitalized Patients: Specific Risk Factors in a High-Risk Population?
Infection 33: 320-326
Wendt, C., D. Lin, H. von Baum. 2005
Risk Factors for Colonization with Third-Generation Cephalosporin-Resistant Enterobacteriaceae.
Infection 33: 327-332
Wendt, C., D. Svoboda, C. Schmidt, O. Bock-Hensley, H. von Baum. 2005
Characteristics that promote transmission of Staphylococcus aureus in german nursing homes.
Infect Cont Hosp Ep 26: 816-821
Weseler, A., H.K. Geiss, R. Saller, J. Reichling. 2005
A novel colorimetric broth microdilution method to determine the minimum inhibitory coencentration (MIC) of antibiotics and essential oils against Helicobacter pylori
Pharmazie 60: 498-502
Witte, W., C. Braulke, C. Cuny, B. Strommenger, G. Werner, D. Heuck, U. Jappe, C. Wendt, H.J. Linde, D. Harmsen. 2005
Emergence of methicillin-resistant Staphylococcus aureus with Panton-Valentine leukocidin genes in central Europe.
Eur. J. Clin. Microbiol. Infect. Dis. 24: 1-5
Publikationen 2004
Ahmad-Nejad, P., S. Mrabet-Dahbi, K. Breuer, M. Klotz, T. Werfel, U. Herz, K. Heeg, M. Neumaier, H. Renz. 2004
The toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype.
J.Allergy Clin.Immunol. 113: 565-567
Albrecht, I., T. Tapmeier, S. Zimmermann, M. Frey, K. Heeg, A. Dalpke. 2004
Toll-like receptor (TLR) selective nucleosomal remodeling at the IL-12p40 promoter.
EMBO Reports 5: 172-177
Arvand, M., R. Feldhues, M. Mieth, T. Kraus, P. Vandamme 2004
Chronic Cholangitis Caused by Bordetella hinzii in a Liver Transplant Recipient.
J.Clin.Microbiol. 42.5: 2335-2337
Baetz, A., M. Frey, K. Heeg, A. Dalpke. 2004
Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells.
J.Biol.Chem. 279: 54708-54715
Bartz, H., Y. Mendoza, M. Gebker, T. Fischborn, K. Heeg, A. Dalpke. 2004
Poly-guanosine strings improve cellular uptake and stimulatory activity of phosphodiester CpG oligonucleotides in human leukocytes.
Vaccine 23: 148-155
Beyer, M., H. Bartz, K. Horner, S. Doths, C. Koerner-Rettberg, J. Schwarze. 2004
Sustained increases in numbers of pulmonary dendritic cells after respiratory syncytial virus infection
J Allergy Clin. Immunol. 113: 127-33
Dalpke, A., K. Heeg. 2004
CpG DNA as immune response modifier.
Int.J.Med.Microbiol. 294: 345-354
Erdinger, L., I. Dörr, M. Dürr, K.A. Höpker. 2004
Analysis of Mutagenic Activity of Airborne Particulate Matter, Standard Reference Materials and Nitrated PAHs using Base Pair-specific Salmonella Typhimurium Tester Strains.
Mutat. Res. 564: 149-157
Erdinger, L., O. Eckl, F. Ingel, Sh. Khussainova, E. Genova, M. Mann, Th. Gabrio. 2004
The Aral Sea Desaster - Human Biomonitoring of Hg, As, HCB, DDE, and PCBs from Children living in Aralsk and Akchi, Kazakstan.
Int.J.Hyg.Env.Health 207: 541-547
Erdinger, L., K. Kühn, R. Feldhues, T. Fröbel, B. Nohynek, Th. Gabrio. 2004
Pathways of THM uptake in swimming pools.
Int.J.Hyg.Env.Health 207: 571-575
Ganten, T.M., H.K. Geiss, W. Stremmel. 2004
Infektionen in der Gastroenterologie.
Unimed-Verlag Bremen ISBN 3895997056
Geiss, H.K. 2004
Gramnegative Kokken. In: D. Adam, H.W. Doerr, H. Linik, H. Lode.
Die Infektiologie. Springer-Verlag, Heidelberg , 958-961
Geiss, H.K. 2004
Meningokokkenerkrankungen. In: R.W. Braun, G.-D. Burchardt, E. Fröhlich, H.D. Nothdurft.
Reise- und Tropenmedizin. Schattauer Verlag Stuttgart, 124-128
Geiss, H.K., D. Mack, H. Seifert. 2004
Identifizierung von speziellen Resistenzmechanismen und zur Interpretation von Ergebnissen der Antibiotikaempflichkeitstestung bei grampositiven und grammnegativen Erregern.
Chemother J. 13(1): 1-16
Hanley, P. J., B. Musset, V. Renigunta, S. H. Limberg, A. Dalpke, R. Sus, K. Heeg, R. Preisig-Müller, J. Daut. 2004
Extracellular ATP induces oscillations of intracellular Ca2+ and membrane potential and promotes transcription of IL-6 in macrophages.
P.Natl.Acad.Sci.USA 101: 9479-9484
Hegele, A., A. Dalpke, P. Barth, Z. Varga, K. Heeg, R. Hofmann, P. Olbert. 2004
Antineoplastic effect of immunostimulatory DNA (CpG-DNA) in a murine C57-BL6/MB-49 transitional cell carcinoma model.
Anticancer Res. 24: 2225-2230
Heeg, K., S. Zimmermann, A. Dalpke. 2004
Microbial Adjuvants.
In: Novel Vaccination Strategies.
Kaufmann, S.H.E. (ed.)
Wiley-VCH, Weinheim, pp. 115-128.
Hollert, H., B. Braun, S. Mijovic, M., Rakaj, A. Rastall, T.B. Seiler, L. Erdinger. 2004
The EULIMNOS project: strengthening cross-border scientific research and higher education in the Lake Shkodra/Skadar Region.
Environ.Sci.Pollut.Res.Int. 11: 135
Jappe, U., D. Petzoldt, C. Wendt. 2004
Methicillin-resistant Staphylococcus aureus Colonization in Inflammatory versus Non-inflammatory Skin Disease: Who should be screened? 2004
Acta Derm.Venereol. 84(3): 181-186
Klee, N., L. Gustavsson, Th. Kosmehl, M. Engwall, L. Erdinger, Th. Braunbeck, H. Hollert. 2004
Toxicity and genotoxicity in an industrial sewage sludge containing nitro- and amino-aromatic compounds during treatment in bioreactors under different oxygen regimes.
Environ.Sci.Pollut.Res.Int. 11: 313-320
Leaper, D.J., H. van Goor, J. Reilly, N. Petrosillo, H.K. Geiss, A.J. Torres, A. Berger. 2004
Surgical site infection - a European perspective of incidence and economic burden.
Int.Wound J. 1(4): 247-273
Nonnenmacher, C., A. Dalpke, R. Mutters, K. Heeg. 2004
Quantitative detection of periodontopathogens by real-time PCR.
J. Microbiol. Meth. 59: 117-125
Oberdorfer, K., S. Swoboda, A. Hamann, U. Baertsch, K. Kusterer, B. Born, T. Hoppe-Tichy, H.K. Geiss, H. von Baum. 2004
Tissue and serum levofloxacin concentrations in diabetic foot infection patients.
J.Antimicrob.Chemother. 54(4): 836-839
Pawlowski, S., T. Ternes, M. Bonerz, A,. Rastall, L. Erdinger. 2004
Estrogenicity of solid phase-extracted water samples from two municipal sewage treatment plant effluents and river Rhine water using the yeast estrogen screen.
Toxicology in Vitro 18: 129-138
Rastall, A., A. Neziri, Z. Vukovic, C. Jung, S. Mijovic, H. Hollert, S. Nikcevic, L. Erdinger. 2004
The identification of readily bioavailable pollutants in Lake Shkodra/Skadar using semipermeable membrane devices (SPMDs), bioassays and chemical analysis.
Environ.Sci.Pollut.Res.Int. 11: 135
Ruderich, F., M. Bauch, M. Haag, J. Heid, F.J. Leven, R. Singer, H.K. Geiss, J. Jünger, B. Tönshoff. 2004
Campus - A flexible interactive system for Web-Based, Problem-Based Learing in Health Care. In: Fieschi et al. (Eds.): MEDINFO2004.
IOS Press, Amsterdam, 921-925
Schaier, M., C. Wendt, M. Zeier, E. Ritz. 2004
Clostridium difficile diarrhoea in the immunsuppressed patient - update on prevention and management.
Nephrol.Dial.Transplant. 19(10): 2432-2436
Schauer, U., S. Hoffjan, T. Rothoeft, H. Bartz, S. König, E. Fuchs, J. Bittscheidt, A. Kochling, V. Stephan. 2004
Severe respiratory syncytial virus infections and reduced interferon-gamma generation in vitro.
Clin. Exp. Immunol. 138(1): 102-109
von Baum, H., D. Lin, C. Wendt. 2004
Prevalence of colonisation with third-generation cephalosporin-resistant Enterobacteriaceae in ICU patients of Heidelberg University Hospitals.
Clin.Microbiol.Infect. 10(5): 436-440
Wendt, C. 2004
Compliance in der Umsetzung von Hygienerichtlinien.
Bundesgesundheitsbl.Gesundheitsforsch.Gesundheitsschutz 47: 329-333
Wendt, C., D. Knautz, H. von Baum. 2004
Differences in Hand Hygiene Behavior Related to the Contamination Risk of Healthcare Activities in Different Groups of Healthcare Workers.
Infect.Control.Hosp.Epidemiol. 25(3): 203-206
Wirtz, V.M., J. Kleeff, S. Swoboda, I. Halaceli, H.K. Geiss, T. Hoppe-Tichy, M.W. Büchler, H. Friess. 2004
Moxifloxacin penetration into human gastrointestinal tissues.
J. Antimicrob. Chemother. 53: 875-877
Yücel, N., R. Lefering, M. Maegele, M. Max, R. Rossaint, A. Koch, R. Schwarz, M. Korenkov, J. Beuth, A. Bach, J. Schierholz, G. Pulverer, E.A. Neugebauer. 2004
Reduced colonization and infection with miconazole-rifampicin modified central venous catheters: a randomized controlled clinical trial.
J.Antimicrob.Chemother. 54(6): 1109-1115
Publikationen 2003
Bock, M., O. Nolte, W. Hartschuh, U. Jappe, H.G. Sonntag. 2003
Lupus vulgaris in a skin graft.
Acta derm. venereol. 83: 132-133
Chaberny, I.F., P. Schnitzler, H.K. Geiss, C. Wendt. 2003
An outbreak of epidemic keratoconjunctivitis in a pediatric unit due to adenovirus type 8.
Infect. Cont. Hosp. Ep. 24>:514-519
Häfner, B., H. Haag, H.K. Geiss, O. Nolte. 2003
Different molecular methods for the identification of rarely isolated non-tuberculous mycobacteria and description of new hsp65 restriction fragment length polymorphism patterns.
Mol. Cell. Probes 18: 59-65
Nolte, O., M. Müller, S. Reitz, S. Ledig, I. Ehrhard, H.G. Sonntag. 2003
Description of new mutations in the rpoB gene in Rifampicin resistant Neisseria meningitidis selected in vitro in a step wise manner.
J. Med. Microbiol. 52: 1077-1081
Swoboda, S., K. Oberdorfer, F. Klee, T. Hoppe-Tichy, H. von Baum, H.K. Geiss. 2003
Tissue and serum concentrations of levofloxacin 500 mg administered intravenously or orally for for antibiotic prophylaxis in biliary surgery.
J.Antimicrob.Chemother. 51: 459-462
Wagner, J., M. Jabbusch, M. Eisenblätter, H. Hahn, C. Wendt, R. Ignatius. 2003
Susceptibilities of Campylobacter jejuni isolates from Germany to ciprofloxacin, moxifloxacin, erythromycin, clindamycin and tetracycline.
Antimicrob. Agents Ch. 47: 2358-2361