Startseite Universitätsklinikum Heidelberg
Startseite Universitätsklinikum Heidelberg Klinik für Allgemeine Psychiatrie Zentrum für Psychosoziale Medizin
Klinik für Allgemeine Psychiatrie Zentrum für Psychosoziale Medizin
Kliniken &… Kliniken Psychosoziale Medizin… Allgemeine… Über uns Sektionen Kognitive… Aktuelle…
Kognitive Neuropsychiatrie

Aktuelle Publikationen

Sektion kognitive Neuropsychiatrie

  1. Hirjak D, Foucher JR, Ams M, Jeanjean LC, Kubera KM, Wolf RC, Northoff G (2023) The historical roots of catatonia – clinical and scientific lessons from Karl Ludwig Kahlbaum’s epoch. Schizophrenia Research, in press 
  2. Kasper J, Eickhoff SB, Caspers S, Peter J, Dogan I, Wolf RC, Reetz K, Dukart J, Orth M (2023) Local synchronicity in dopamine-rich caudate nucleus influences Huntington's disease motor phenotype. Brain, doi: 10.1093/brain/awad043. Online ahead of print
  3. Hirjak D, Ams M, Gass P, Kubera KM, Sambataro F, Foucher JR, Northoff G, Wolf RC (2023) Historical postmortem studies on catatonia: Close reading and analysis of Kahlbaum’s cases and scientific texts between 1800 and 1900. Schizophr Res, accepted April 5th 2023
  4. Brandt GA, Fritze S, Krayem M, Daub J, Volkmer S, Kukovic J, Meyer-Lindenberg A, Northoff G, Kubera KM, Wolf RC, Hirjak D (2023) Extension, translation and preliminary validation of the Northoff Scale for Subjective Experience in Catatonia (NSSC). Schizophr Research, in press
  5. Trevisan N, Cattarinussi G, Olivo D, Di Ciano A, Giudetti L, Pampallona A, Kubera KM, Hirjak D, Wolf RC, Sambataro F (2023) Neural Correlates of Antisocial Behavior: The Victim’s Perspective. Brain Sciences, 13, 474. doi.org/10.3390/brainsci13030474
  6. Kubera KM, Rashidi M, Schmitgen MM, Barth A, Hirjak D, Otte ML, Sambataro F, Calhoun VD, Wolf RC (2023) Functional network interactions in patients with schizophrenia with persistent auditory verbal hallucinations: a multimodal MRI fusion approach using three-way pICA. Schizophr Research, in press
  7. Depping M, Köhler-Ipek L, Ullrich P, Hauer K, Wolf RC (2023) Depression im Alter und Frailty epidemiologische, klinische und neurobiologische Zusammenhänge. Der Nervenarzt, accepted Feb. 202
  8. Wolf RC, Werler F, Schmitgen MM, Wolf ND, Wittemann M, Reith W, Hirjak D (2023) Functional correlates of neurological soft signs in heavy cannabis users. Addiction Biology, accepted Jan. 2023
  9. Hirjak D, Fricchione G, Wolf RC, Northoff G (2023) Lorazepam in catatonia – past, present and future of a clinical success story. Schizophrenia Research, accepted Feb. 7th 2023
  10. Otte ML, Schmitgen MM, Wolf ND, Kubera KM, Calhoun VD, Fritze S, Geiger LS Tost H, Seidl UW, Meyer-Lindenberg A, Hirjak D, Wolf RC (2023) Structure/function interrelationships and illness insight in patients with schizophrenia: a multimodal MRI data fusion study. European Archives of Psychiatry and Clinical Neuroscience, accepted for publication Jan 23rd  
  11. Wolf RC, Werler F, Schmitgen MM, Wolf ND, Wittemann M, Reith W, Hirjak D (2023) Functional correlates of neurological soft signs in heavy cannabis users. Addiction Biology, accepted Jan 20th 2023
  12. Henemann G, Schmitgen MM, Wolf ND, Hirjak D, Kubera KM, Sambataro F, Bach P, Koenig J, Wolf RC (2023) Cognitive domain-independent aberrant frontoparietal network strength in individuals with excessive smartphone use. Psychiatry Res Neuroimaging, accepted for publication Jan 12th 2023
  13. Kubera KM, Schmitgen MM, Hildebrandt V, Neukel C, Otte ML, Sicorello M, Steinmann S, Herpertz SC, Wolf RC (2023) Structural correlates of life-time “voice-hearing” in patients with borderline personality disorder: a pilot study. Neuropsychobiology, in press (
  14. Hirjak D, Brandt GA, Fritze S, Kubera KM, Northoff G, Wolf RC (2023) Distribution and frequency of clinical criteria and rating scales for diagnosis and assessment of catatonia in different study types. Schizophr Research, in press
  15. Cattarinussi G, Gugliotta A, Hirjak D, Wolf RC, Sambataro F (2023) Neuroimaging alterations in catatonia: a systematic review. Schizophrenia Research, 8:S0920-9964(22)00407-8. doi: 10.1016/j.schres.2022.11.002. Online ahead of print
  16. Renz MP, Zidda F, Andoh J, Prager M, Sack M, Becker R, Ruf M, Schmitgen MM, Wolf RC, Meyer-Lindenberg A, Tost H (2023) Practical challenges of continuous real-time fMRI neurofeedback with multi-band accelerated echo-planar imaging and short repetition times. Human Brain Mapping, doi: 10.1002/hbm.26154. Online ahead of print
  1. Sambataro F, Wolf RC (2022) Time after time: Electroconvulsive therapy modulates the brain’s functional network connectivity dynamics. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 7(3):243-245
  2. Rashidi M, Maier E, Dekel S, Sütterlin M, Wolf RC, Ditzen B, Grinevich V, Herpertz SH (2022) Peripartum effects of synthetic oxytocin: The good, the bad, and the unknown. Neurosci Biobehav Rev, 141:104859. doi: 10.1016/j.neubiorev.2022.104859 
  3. Wolf RC, Fahmy, R, Wasfi M, Mamdouh R, Moussa K, Wahba A, Schmitgen MM, Wolf ND, Hirjak D, Sambataro F, Kubera KM (2022) Effects of mindfulness-based interventions on gray matter volume in patients with opioid dependence. Neuropsychobiology, 81(6):531-538
  4. Foucher JR, Jeanjean LC, Bartsch AJ, Humbert I, de Billy CC, Obrecht A, Mainberger O, Clauss JME, Waddington JL, Wolf RC, Hirjak D, Morra C, Ungvari G, Schorr B, Berna F, Shorter E (2022) Paratonia, Gegenhalten and psychomotor hypertonia: Back to the roots. Schizophrenia Research, S0920-9964(22)00332-2. doi: 10.1016/j.schres.2022.08.026. Online ahead of print
  5. Henemann G, Schmitgen MM, Wolf ND, Hirjak D, Kubera KM, Sambataro F, Leménager T, Koenig J, Wolf RC (2022) Neurochemical correlates of cue reactivity in individuals with excessive smartphone use. Eur Addiction Res, Dec 5;1-5. doi: 10.1159/000527095. Online ahead of print
  6. Cattarinussi G, Kubera KM, Hirjak D, Wolf RC, Sambataro F (2022) Neural correlates of the risk for Schizophrenia and Bipolar Disorder: a meta-analysis of structural and functional neuroimaging studies. Biol Psychiatry, 92(5):375-384
  7. Hirjak D, Henemann GM, Schmitgen MM, Götz L, Wolf ND, Kubera KM, Sambataro F, Lemenager T, Koenig T, Wolf RC (2022) Cortical surface variation in individuals with excessive smartphone use. Developmental Neurobiology, 82(4):277-287
  8. Schmitgen MM, Wolf ND, Sambataro F, Hirjak D, Kubera KM, Koenig J, Wolf RC (2022) Aberrant intrinsic neural network strength in individuals with "smartphone addiction": an MRI data fusion study. Brain & Behavior, 12(9):e2739. doi: 10.1002/brb3.2739
  9. Hirjak D, Meyer-Lindenberg A, Sambataro F, Wolf RC (2022) Multiparametric assessment of sensorimotor abnormalities in vulnerable populations: A window of opportunity. Neurosci Biobehav Rev, 137:104658. doi: 10.1016/j.neubiorev.2022.104658
  10. Fritze S, Brandt GA, Kubera KM, Schmitgen MM, Northoff G, Geiger-Primo LS, Meyer-Lindenberg A, Wolf RC*, Hirjak D* (2022) Structural alteration of amygdala and hypothalamus contribute to catatonia. Schizophrenia Research, S0920-9964(22)00165-7. doi: 10.1016/j.schres.2022.05.003 * shared senior authorship
  11. Hirjak D, Foucher JR, Ams M, Jeanjean L, Kubera KM, Wolf RC, Northoff G (2022) The origins of catatonia – Systematic review of historical texts between 1800 and 1900. Schizophrenia Research, S0920-9964(22)00208-0. doi: 10.1016/j.schres.2022.06.003
  12. Hirjak D, Wolf RC, Landwehrmeyer GB, Northoff G (2022) Catatonia: Looking back and moving forward. Brain, 145(9):2939-2942
  13. Otte M, Schmitgen MM, Kubera KM, Wolf ND, Fritze S, Geiger LS, Tost H, Seidl UW, Meyer-Lindenberg A, Hirjak D, Wolf RC (2022) Cortical morphology and illness insight in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, doi: 10.1007/s00406-021-01328-x
  14. Fritze S, Sambataro F, Kubera KM, Brandt GA, Meyer-Lindenberg A, Wolf RC*, Hirjak* (2022) Characterizing the sensorimotor domain in schizophrenia spectrum disorders. European Archives of Psychiatry and Clinical Neuroscience, doi: 10.1007/s00406-021-01354-9 * shared senior authorship.
  15. Hirjak D, Schmitgen MM, Werler F, Wittemann M, Kubera KM, Wolf ND, Sambataro F, Calhoun VD, Reith W, Wolf RC (2022) Multimodal MRI data fusion reveals distinct structural, functional and neurochemical correlates of heavy cannabis use. Addiction Biology, doi: 10.1111/adb.13113
  16. Foucher JR, Jeanjean LC, de Billy CC, Pfuhlmann B, Clauss JME, Roth NJ, Obrecht A, Mainberger O, Vernet R, Arcay H, Schorr B, Weibel S, Walther S, van Harten PN, Waddington JL, Cuesta MJ, Peralta V, Dupin L, Sambataro F, Morrens M, Kubera KM, Pieters LE, Stegmayer K, Strik W, Wolf RC, Franzek EJ, Jabs BE, Ams M, Garcia C, Hanke M, Elowe J, Bartsch A, Berna F, Hirjak D (2022) The polysemous concepts of psychomotricity and catatonia: a European multi-consensus perspective. European Neuropsychopharmacology, 56: 60–73 (
  17. Hirjak D, Sambataro F, Northoff G, Wolf RC (2022) Different faces of catatonia and how to approach them. European Archives of Psychiatry and Clinical Neuroscience, 272: 1385–1387
  18. Trevisan N, Miola A, Cattarinusi G, Kubera KM, Hirjak D, Wolf RC, Sambataro F (2022) Cortical complexity is distinctively altered in schizophrenia and bipolar disorder. Schizophrenia Research, 241: 92-93
  1. Sambataro F, Hirjak D, Fritze S, Kubera KM, Northoff G, Calhoun VD, Meyer-Lindenberg A, Wolf RC (2021) Intrinsic neural network dynamics in catatonia. Human Brain Mapping, 42(18):6087-6098  
  2. Rashidi M, Schmitgen MM, Weisbrod M, Schnell K, Wolf RC*, Whittington M* (2021) Right parietotemporal activity predicts sense of agency under uncertain delays of sensory outcomes. Journal of Neurophysiology, 125(3):903-914 * shared senior authorship. 
  3. Schneider I, Neukel C, Bertsch K, Fuchs A, Möhler E, Zietlow AL, Brunner R, Wolf RC, Herpertz SC (2021) Early life maltreatment affects intrinsic neural function in mothers. Journal of Psychiatric Research, 143 (2021) 176–182 
  4. Hirjak D, Meyer-Lindenberg A, Sambataro F, Fritze S, Kukovic J, Kubera KM, Wolf RC (2021) Progress in sensorimotor neuroscience of schizophrenia spectrum disorders: lessons learned and future directions. Progress in Neuropsychopharmacology and Biological Psychiatry, doi: 10.1016/j.pnpbp.2021.110370 
  5. Javaheripour N, Li M, chand T, Dannlowski U, Frodl T, Gotlib IH, Grimm S, Hahn T, Hamilton JP, Harrison B, Hyett MP, Kicher T, Krug A, Nenadic I, Olbrich S, Parker G, Pezawas L, Sacchet MD, Sämann P, van Wingen G, Walter H, Wolf RC, Walter M, Wagner G (2021) Altered resting-state functional connectome in major depressive disorder: a mega-analysis from the PsyMRI consortium. Translational Psychiatry, 11(1):511 
  6. Korn C, Wolf RC (2021) Negative Valenzsysteme im System der Research Domain Criteria (RDoC). Der Nervenarzt, 92(9):868-877 
  7. Kubera KM, Hirjak D, Wolf ND, Wolf RC (2021) Kognitive Kontrolle im RDoC-System: Klinische Implikationen für verbale akustische Halluzinationen. Der Nervenarzt, 92(9):892-906 
  8. Hirjak D, Fritze S, Northoff G, Kubera KM, Wolf RC (2021) Die sensomotorische Domäne im RDoC-System: Fortschritte und Perspektiven. Der Nervenarzt, 92(9):915-924 
  9. Wolf RC, Werler F, Wittemann M, Schmitgen MM, Kubera KM, Wolf ND, Reith W, Hirjak D (2021) Structural correlates of sensorimotor dysfunction in heavy cannabis users. Addiction Biologyy, 26(5):e13032, doi: 10.1111/adb.13032 
  10. Hirjak D, Meyer-Lindenberg A, Sambataro F, Wolf RC (2021) Sensorimotor neuroscience in mental disorders: Progress, perspectives and challenges. Schizophrenia Bulletin, accepted April 10th 2021 
  11. Wasserthal J, Maier-Hein KH, Neher PF, Wolf RC, Northoff G, Waddington JL, Kubera KM, Fritze S, Harneit A, Geiger LS, Tost H, Hirjak D (2021) White matter microstructure alterations in cortico-striatal networks are associated with parkinsonism in schizophrenia spectrum disorders. European Neuropsychopharmacology, 50:64-74 
  12. Hirjak D, Sartorius A, Kubera KM, Wolf RC (2021) Antipsychotic-induced catatonia and neuroleptic malignant syndrome: The dark side of the moon. Molecular Psychiatry, https://doi.org/10.1038/s41380-021-01158-2 
  13. Wolf RC, Kubera KM, Waddington JL, Schmitgen MM, Fritze S, Rashidi M, Thieme CE, Sambataro F, Geiger LS, Tost H, Hirjak D (2021) A neurodevelopmental signature of parkinsonism in schizophrenia. Schizophrenia Research, 231:54-60 
  14. Thomann AK, Schmitgen MM, Kmuche D, Ebert MP, Thomann PA, Szabo K, Gass A, Griebe M, Reindl W, Wolf RC (2021) Exploring joint patterns of brain structure and function in inflammatory bowel diseases using multimodal data fusion. Neurogastroenterology and Motility, 33:e14078. doi: 10.1111/nmo.14078 
  15. Northoff G, Hirjak D, Wolf RC, Magioncalda P, Martino M (2021) Why is there symptom coupling of psychological and motor changes in psychomotor mechanisms? Insights from the brain’s topography. Molecular Psychiatry, https://doi.org/10.1038/s41380-020-00945-7 
  16. Wolf RC, Rashidi M, Schmitgen MM, Fritze S, Sambataro F, Kubera KM, Hirjak D (2021) Neurological soft signs predict auditory verbal hallucinations in patients with schizophrenia. Schizophrenia Bulletin, sbaa146. doi: 10.1093/schbul/sbaa146 
  17. Olivo D, Di Ciano A, Mauro J, Giudetti L, Pampallona A, Kubera KM, Hirjak D, Wolf RC, Sambataro F, (2021) Neural responses of benefitting from the prosocial exchange: the effect of helping-behavior. Frontiers in Psychology, https://doi.org/10.3389/fpsyg.2021.606858 
  18. Fritze S, Harneit A, Waddington JL, Kubera KM, Schmitgen MM, Otte ML, Geiger LS, Tost H, Meyer-Lindenberg A, Wolf RC*, Hirjak D* (2021) Structural alterations in brainstem, basal ganglia and thalamus associated with parkinsonism in schizophrenia spectrum disorders. European Archives of Psychiatry and Clinical Neuroscience, 271(8):1455-1464 * shared senior authorship.
  19. Hirjak D, Wolf RC (2021) „Schizotype Störung“ In: Bauer M, Meyer-Lindenberg A, Kiefer F, Philipsen A (Hrsg.)  Referenz Psychische Erkrankungen, MN314590101, in press, Thieme Verlag, Stuttgart 
  20. Hildebrandt V, Huber M, Wolf RC (2021) Neuronale Korrelate wahnhafter Störungen. NeuroTransmitter, NeuroTransmitter, 32(5):37-40 
  21. Hirjak D, Wolf RC (2021) Neurologische Soft Signs bei psychischen Störungen. InFo Neurologie & Psychiatrie, 23(10):60-64.
Kognitive Neuropsychiatrie
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