AG Lohmann

Selected Original Research Articles

Binder M, Kochs G, Bartenschlager R, Lohmann V., 2007.
Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy. Hepatology. 2007 Nov;46(5):1365-74.

Binder M, Quinkert D, Bochkarova O, Klein R, Kezmic N, Bartenschlager R, Lohmann V. 2007.
Identification of determinants involved in initiation of hepatitis C virus RNA synthesis by using intergenotypic replicase chimeras. J Virol. 2007 May;81(10):5270-83. Epub 2007 Mar 7.

Schaller T, Appel N, Koutsoudakis G, Kallis S, Lohmann V, Pietschmann T, Bartenschlager R., 2007.
Analysis of hepatitis C virus superinfection exclusion by using novel fluorochrome gene-tagged viral genomes. Journal of Virology, Feb 14; Epub 2007 Feb 14.

Koo BC, McPoland P, Wagoner JP, Kane OJ, Lohmann V, Polyak SJ., 2006.
Relationships between hepatitis C virus replication and CXCL-8 production in vitro. Journal of Virology, Aug;80(16):7885-93.

Koutsoudakis G, Kaul A, Steinmann E, Kallis S, Lohmann V, Pietschmann T, Bartenschlager R., 2006.
Characterization of the early steps of hepatitis C virus infection by using luciferase reporter viruses. Journal of Virology, Jun;80(11):5308-20.

Quinkert, D., R. Bartenschlager, and V. Lohmann, 2005.
Quantitative analysis of the hepatitis C virus replication complex. Journal of Virology, 79:13594-13605.

Meylan, E., J. Curran, K. Hofmann, D. Moradpour, M. Binder, R. Bartenschlager and J. Tschopp. 2005.
Cardif is a novel adaptor protein in RIG-I-mediated antiviral responses targeted by hepatitis C virus. Nature, 437:1167-1172.

Windisch, M., M. Frese, A. Kaul, M. Trippler, V. Lohmann, and R. Bartenschlager. 2005.
Dissecting the Interferon-Induced Inhibition of Hepatitis C Virus Replication by Using a Novel Host Cell Line. Journal of Virology, 79:13778-13793.

Aus dem Siepen M., V. Lohmann, M. Wiese, S. Ross, M. Roggendorf, and S. Viazov. 2005.
Nonstructural protein 5A does not contribute to the resistance of hepatitis C virus replication to interferon alpha in cell culture. Virology 336:131-136.

Moradpour, D., V. Brass, E. Bieck, P. Friebe, R. Gosert, H. E. Blum, R. Bartenschlager, F. Penin, and V. Lohmann. 2004.
Membrane association of the RNA-dependent RNA polymerase is essential for hepatitis C virus RNA replication. J. Virol. 78:13278-13284.

Lohmann, V., S. Hoffmann, U. Herian, F. Penin and R. Bartenschlager. 2003.
Viral and cellular determinants of hepatitis C virus RNA replication in cell culture. Journal of Virology 77:3007-3019.

Pietschmann, T., V. Lohmann, A. Kaul, N. Krieger, G. Rinck, G. Rutter, D. Strand und R. Bartenschlager. 2002.
Persistent and transient replication of full-length hepatitis C virus genomes in cell culture. Journal of Virology, 76:4008-4021.

Friebe, P., V. Lohmann, N. Krieger and R. Bartenschlager. 2001.
Sequences in the 5' non-translated region of the hepatitis C virus required for RNA replication. Journal of Virology, 75:12047-12057.

Krieger, N., V. Lohmann and R. Bartenschlager. 2001.
Enhancement of hepatitis C virus RNA replication by cell culture adaptive mutations. Journal of Virology, 75:4614-4624.

Lohmann, V., F. Körner, A. Dobierzewska and R. Bartenschlager. 2001.
Mutations in hepatitis C virus RNAs conferring cell culture adaptation. Journal of Virology, 75:1437-1449.

Pietschmann, T., V. Lohmann, G. Rutter, K. Kurpanek and R. Bartenschlager. 2001.
Characterization of cell lines carrying self-replicating hepatitis C virus RNAs. Journal of Virology, 75:1252-1264.

Lohmann, V., F. Körner, J.O. Koch, U. Herian, L. Theilmann and R. Bartenschlager. 1999.
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science, 285:110-113.

Lohmann, V., H. Overton and R. Bartenschlager. 1999.
Selective Stimulation of Hepatitis C Virus and Pestivirus NS5B RNA Polymerase Activity by GTP. Journal of Biological Chemistry, 274:10807-10815.

Lohmann, V., A. Roos, F. Körner, J. O. Koch, and R. Bartenschlager. 1998.
Biochemical and kinetic analyses of NS5B RNA-dependent RNA polymerase of the hepatitis C virus. Virology 249:108-118.

Lohmann, V., F. Körner, U. Herian and R. Bartenschlager. 1997.
Biochemical properties of hepatitis C virus RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity. Journal of Virology, 71:8416-8428.

Selected Reviews

Thimme, R., V. Lohmann, and F. Weber. 2006.
A target on the move: Innate and adaptive immune escape strategies of hepatitis C virus. Antiviral Res. 69:129-141.

Bartenschlager, R. and V. Lohmann. 2001.
Novel cell culture systems for the hepatitis C virus. Antiviral Res. 52:1-17.

Bartenschlager, R. and V. Lohmann. 2000.
Replication of hepatitis C virus. Journal of General Virology, 81:1631-1648.