AG Urban

Selected Original Research Articles

Urban S., 2008
New insights into hepatitis B and hepatitis delta virus entry; Future Virology, May 2008, Vol. 3, No. 3, Pages 253-264

Petersen J, Dandri M, Mier W, Lütgehetmann M, Volz T, von Weizsäcker F, Haberkorn U, Fischer L, Pollok JM, Erbes B, Seitz S,
Urban S., 2008
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein. Nat Biotechnol. 2008 Mar;26(3):335-41. Epub 2008 Feb 24

Schulze A, Gripon P, Urban S. 2007.
Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans. Hepatology. 2007 Dec;46(6):1759-68.

Seitz S, Urban S, Antoni C, Böttcher B. 2007.
Cryo-electron microscopy of hepatitis B virions reveals variability in envelope capsid interactions. EMBO J. 2007 Sep 19;26(18):4160-7. Epub 2007 Aug 30.

Glebe D, Urban S. 2007.
Viral and cellular determinants involved in hepadnaviral entry. World J Gastroenterol. 2007 Jan 7;13(1):22-38. Review.

Engelke, M., Mills, K., Seitz, S., Simon, P., Gripon, P., Schnölzer, M., Urban, S. 2006.
Characterization of a hepatitis B and hepatitis delta virus receptor binding site. Hepatology, 43(4):750-760

Glebe, D.*, Urban, S.*, Knoop, E.V., Cag, N., Krass, P., Grün, S., Bulavaite, A., Sasnauskas, K., Gerlich, W.H. 2005.
Mapping of the hepatitis B virus attachment site by infection-inhibiting preS1 lipopeptides using primary Tupaia hepatocytes. Gastroenterology, 129(1):234-245 (*first and second author contributed equally to this work).

Gripon, P., Cannie, I., Urban, S. 2005.
Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface protein. J. Virol., 79 (3), 1613-1622.

Urban, S. 2004.
Binding of duck Carboxypeptidase D (gp180) to duck hepatitis B virus (DHBV). Meth. Mol. Med., (95) 199-212.

Gripon, P., Rumin, S., Urban, S., LeSeyec, J., Glaise, D., Cannie, I., Guyomard, C., Lucas, J., Trepo, C. and Guguen-Guillouzo. 2002.
Infection of a human hepatoma cell line by Hepatitis B Virus. PNAS, 99 (24) 15655-15660.

Urban, S. and Gripon, P. 2002.
Inhibition of duck hepatitis B virus infection by myristoylated preS peptides of the large viral surface protein. J. Virol., 76 (4), 1986-1990.

Breiner, K.M.*, Urban, S*., Glass, B. and Schaller, H. 2001.
Envelope protein-mediated down-regulation of a hepatitis B virus receptor in infected hepatocytes. J. Virol., 75 (1), 143-150 (*first and second author contributed equally to this work).

Urban, S., Schwarz, C., Marx, U. C., Zentgraf, H., Schaller, H. and Multhaup, G. 2000.
Receptor recognition by a hepatitis B virus reveals a novel mode of high-affinity virus-receptor interaction. EMBO J., 19 (6), 1217-1227.

Urban, S., Kruse, C. and Multhaup. G. 1999.
A soluble form of the avian hepatitis B virus receptor: Biochemical characterization and functional analysis of the receptor ligand complex. J. Biol. Chem., 274 (9), 5707-5715.

Urban, S., Breiner, K.M., Fehler, F., Klingmüller, U. and Schaller, H. 1998.
Avian hepatitis B virus infection is initiated by the interaction of a distinct pre-S subdomain with its cellular receptor gp180. J. Virol., 72 (10), 8089-8097.

Breiner, K. M., Urban, S. and Schaller, H. 1998.
Carboxypeptidase D (gp180), a Golgi-resident protein, functions in the attachment and entry of avian hepatitis B viruses. J. Virol., 72 (10), 8098-8104.

Sirma, H., Weil, R., Rosmorduc, O., Urban, S., Israel, A., Kremsdorf, D. and Bréchot, C. 1998.
Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome. Oncogene, 16 (16), 2051-2063.

Poussin, K., Dienes, H., Sirma, H., Urban, S., Beaugrand, M., Franco, D., Schirmacher, P., Bréchot, C. and Paterlini-Bréchot, P. 1999.
Expression of mutated Hepatitis B virus X genes in human hepatocellular carcinomas. Intl. J. Cancer, 80, 497-505.

Urban, S., Hildt, E., Eckerskorn, C., Sirma, H., Kekulé, A. and Hofschneider, P.H. 1997.
Isolation and molecular characterization of Hepatitis B Virus X-protein from a baculovirus expression system. Hepatology, 26 (4), 1045-1053.

Kesel, A.J., Urban, S. and Oberthuer, W. 1996.
Interconvertible (Z/E)-stereoisomers of a vitamin B6 coemzyme analog derived from pyridoxal 5´-phosphate and rhodanine. Tetrahedron, 52 (47), 14787-14800.

Hildt, E., Urban, S., Eckerskorn, C. and Hofschneider, P.H. 1996.
Isolation of highly purified, functional carboxy-terminally truncated hepatitis B virus middle surface protein activators from eucaryotic expression systems. Hepatology, 24 (3), 502-507.

Hildt, E., Hofschneider, P.H., and Urban, S. 1996.
The role of Hepatitis B Virus (HBV) in the development of hepatocellular carcinoma. (Review). Seminars in Virology, 7 (5), 333-347.

Urban, S., Hildt, E., Kellermann, J. and Hofschneider, P.H. 1995.
Detection of cellular binding proteins of the hepatitis B virus X-protein by affinity chromatography. Journal of Cancer Research and Clinical Oncology, 121, Suppl. 1, S16.

Hildt, E., Urban, S. and Hofschneider, P.H. 1995.
Characterization of essential domains for the functionality of the MHBst transcriptional activator and identification of a minimal MHBst activator. Oncogene, 11(10), 2055-2066.

Hildt, E., Urban, S., Lauer, U., Hofschneider, P.H. and Kekulé, A.S. 1993.
ER-localization and functional expression of the HBV transactivator MHBst. Oncogene, 8 (12), 3359-3367.

Bohley, P., Kopitz, J., Adam, G., Rist, B., von Appen, F. and Urban, S. 1991.
Post-translational arginylation and intracellular proteolysis. Biomed. Biochim. Acta, (50) 343-346.