Publications

Breithaupt MH, Krohmer E, Taylor L, Koerner E, Hoppe-Tichy T, Burhenne J, Foerster KI, Dachtler M, Huber G, Venkatesh R, Eggenreich K, Czock D, Mikus G, Blank A, Haefeli WE. Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers. Eur J Clin Pharmacol 2022;78:1965-1972.
Grass J, Rose P, Burhenne J, Blank A, Haefeli WE, Mikus G. Absolute bioavailability of microdosed midazolam After buccal administration Is Dependent on buccal exposure time. J Clin Pharmacol 2021;61:472-479.
Sauter M, Uhl P, Burhenne J, Haefeli WE. Application of triple quadrupole tandem mass spectrometry to the bioanalysis of collision-induced dissociation-resistant cyclic peptides - Ultra-sensitive quantification of the somatostatin-analog pasireotide utilizing UHPLC-MS/MS. J Pharm Biomed Anal 2021;194:113728.
Sauter M, Burhenne J, Haefeli WE, Uhl P. An Underestimated Factor: The Extent of Cross-Reactions Modifying APIs in Surface-Modified Liposomal Preparations Caused by Comprised Activated Lipids. Molecules 2020;25:4436.
Sauter M, Uhl P, Burhenne J, Haefeli WE. Ultra-sensitive bioanalysis of the therapeutic peptide exenatide for accurate pharmacokinetic analyses at effective plasma concentrations utilizing UPLC-MS/MS. J Pharm Anal 2020;10:233-239.
Sauter M, Uhl P, Burhenne J, Haefeli WE. Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics. J Pharm Biomed Anal 2020;186:113276.
Sauter M, Uhl P, Burhenne J, Haefeli WE. Post-extraction disulfide bond cleavage for MS/MS quantification of collision-induced dissociation-resistant cystine-cyclized peptides and its application to the ultra-sensitive UPLC-MS/MS bioanalysis of octreotide in plasma. Anal Chim Acta 2020;1114:42-49.
Sauter M, Uhl P, Meid AD, Mikus G, Burhenne J, Haefeli WE. New Insights Into the Pharmacokinetics of Vancomycin After Oral and Intravenous Administration: An Investigation in Beagle Dogs. J Pharm Sci 2020;109:2090-2094.
Kiene K, Hayasi N, Burhenne J, Uchitomi R, Sünderhauf C, Schmid Y, Haschke M, Haefeli WE, Krähenbühl S, Mikus G, Inada H, Huwyler J. Microdosed midazolam for the determination of cytochrome P450 3A activity: development and clinical evaluation of a buccal film. Eur J Pharm Sci 2019;135:77-82.
Sauter M, Uhl P, Foerster KI, Mohr I, Höne RT, Merle U, Burhenne J, Haefeli WE. An ultra-sensitive UHPLC-MS/MS assay for the quantification of orally administered vancomycin in plasma. J Pharm Biomed Anal 2019;174:633-638.
Sauter M, Uhl P, Majewsky M, Fresnais M, Haefeli WE, Burhenne J. An ultrasensitive UPLC-MS/MS assay for the quantification of the therapeutic peptide liraglutide in plasma to assess the oral and nasal bioavailability in beagle dogs. Bioanalysis 2019;11:887-898.